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Amanda L Sharpe

TitleProf,Asst
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentPharmaceutical Sciences
Address1110 N Stonewall Ave
Oklahoma City OK 73117-1200
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    Collapse Research 
    Collapse research activities and funding
    SC3GM121214     (SHARPE, AMANDA L)Feb 15, 2017 - Jan 31, 2021
    NIH/NIGMS
    Proopiomelanocortin neuronal involvement in feeding and reward learning mediated by projections from the arcuate nucleus to the nucleus accumbens
    Role: Principal Investigator

    F32AA014747     (SHARPE, AMANDA L)Dec 1, 2003 - Jun 10, 2005
    NIH/NIAAA
    Ethanol Intake and Hypothalamic CRH Receptor Type 2
    Role: Principal Investigator

    F31AA005566     (SHARPE, AMANDA L)Sep 1, 2000
    NIH/NIAAA
    EXAMINATION OF ALCOHOL AND NICOTINE COADMINISTRATION
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Dominguez-Lopez S, Piccart E, Lynch WB, Wollet MB, Sharpe AL, Beckstead MJ. Antagonism of Neurotensin Receptors in the Ventral Tegmental Area Decreases Methamphetamine Self-Administration and Methamphetamine Seeking in Mice. Int J Neuropsychopharmacol. 2018 Apr 01; 21(4):361-370. PMID: 29272412.
      View in: PubMed
    2. Sharpe AL, Varela E, Beckstead MJ. Systemic PD149163, a neurotensin receptor 1 agonist, decreases methamphetamine self-administration in DBA/2J mice without causing excessive sedation. PLoS One. 2017; 12(7):e0180710. PMID: 28686721.
      View in: PubMed
    3. McCall NM, Kotecki L, Dominguez-Lopez S, Marron Fernandez de Velasco E, Carlblom N, Sharpe AL, Beckstead MJ, Wickman K. Selective Ablation of GIRK Channels in Dopamine Neurons Alters Behavioral Effects of Cocaine in Mice. Neuropsychopharmacology. 2017 02; 42(3):707-715. PMID: 27468917.
      View in: PubMed
    4. Sharpe AL, Varela E, Bettinger L, Beckstead MJ. Methamphetamine self-administration in mice decreases GIRK channel-mediated currents in midbrain dopamine neurons. Int J Neuropsychopharmacol. 2014 Oct 31; 18(5). PMID: 25522412; PMCID: PMC4376542.
    5. Bardgett ME, Sharpe AL, Toney GM. Activation of corticotropin-releasing factor receptors in the rostral ventrolateral medulla is required for glucose-induced sympathoexcitation. Am J Physiol Endocrinol Metab. 2014 Nov 15; 307(10):E944-53. PMID: 25269482; PMCID: PMC4233255.
    6. Sharpe AL, Calderon AS, Andrade MA, Cunningham JT, Mifflin SW, Toney GM. Chronic intermittent hypoxia increases sympathetic control of blood pressure: role of neuronal activity in the hypothalamic paraventricular nucleus. Am J Physiol Heart Circ Physiol. 2013 Dec; 305(12):H1772-80. PMID: 24097432; PMCID: PMC3882549.
    7. Branch SY, Goertz RB, Sharpe AL, Pierce J, Roy S, Ko D, Paladini CA, Beckstead MJ. Food restriction increases glutamate receptor-mediated burst firing of dopamine neurons. J Neurosci. 2013 Aug 21; 33(34):13861-72. PMID: 23966705; PMCID: PMC3755722.
    8. Sharpe AL, Andrade MA, Herrera-Rosales M, Britton SL, Koch LG, Toney GM. Rats selectively bred for differences in aerobic capacity have similar hypertensive responses to chronic intermittent hypoxia. Am J Physiol Heart Circ Physiol. 2013 Aug 01; 305(3):H403-9. PMID: 23709603; PMCID: PMC3742873.
    9. Sharpe AL, Klaus JD, Beckstead MJ. Meal schedule influences food restriction-induced locomotor sensitization to methamphetamine. Psychopharmacology (Berl). 2012 Feb; 219(3):795-803. PMID: 21750897; PMCID: PMC4416415.
    10. Pastor R, Reed C, Burkhart-Kasch S, Li N, Sharpe AL, Coste SC, Stenzel-Poore MP, Phillips TJ. Ethanol concentration-dependent effects and the role of stress on ethanol drinking in corticotropin-releasing factor type 1 and double type 1 and 2 receptor knockout mice. Psychopharmacology (Berl). 2011 Nov; 218(1):169-77. PMID: 21487655; PMCID: PMC3312392.
    11. Sharpe AL, Phillips TJ. Central urocortin 3 administration decreases limited-access ethanol intake in nondependent mice. Behav Pharmacol. 2009 Jul; 20(4):346-51. PMID: 19581799; PMCID: PMC2908376.
    12. Sharpe AL, Low MJ. Proopiomelanocortin peptides are not essential for development of ethanol-induced behavioral sensitization. Alcohol Clin Exp Res. 2009 Jul; 33(7):1202-7. PMID: 19389193; PMCID: PMC2908305.
    13. Sharpe AL, Coste SC, Burkhart-Kasch S, Li N, Stenzel-Poore MP, Phillips TJ. Mice deficient in corticotropin-releasing factor receptor type 2 exhibit normal ethanol-associated behaviors. Alcohol Clin Exp Res. 2005 Sep; 29(9):1601-9. PMID: 16205360.
      View in: PubMed
    14. Sharpe AL, Tsivkovskaia NO, Ryabinin AE. Ataxia and c-Fos expression in mice drinking ethanol in a limited access session. Alcohol Clin Exp Res. 2005 Aug; 29(8):1419-26. PMID: 16131849.
      View in: PubMed
    15. Palmer AA, Sharpe AL, Burkhart-Kasch S, McKinnon CS, Coste SC, Stenzel-Poore MP, Phillips TJ. Corticotropin-releasing factor overexpression decreases ethanol drinking and increases sensitivity to the sedative effects of ethanol. Psychopharmacology (Berl). 2004 Nov; 176(3-4):386-97. PMID: 15138758.
      View in: PubMed
    16. Sharpe AL, Samson HH. Ethanol and sucrose self-administration components: effects of drinking history. Alcohol. 2003 Jan; 29(1):31-8. PMID: 12657374.
      View in: PubMed
    17. Sharpe AL, Samson HH. Repeated nicotine injections decrease operant ethanol self-administration. Alcohol. 2002 Aug; 28(1):1-7. PMID: 12377355.
      View in: PubMed
    18. Sim-Selley LJ, Sharpe AL, Vogt LJ, Brunk LK, Selley DE, Samson HH. Effect of ethanol self-administration on mu- and delta-opioid receptor-mediated G-protein activity. Alcohol Clin Exp Res. 2002 May; 26(5):688-94. PMID: 12045478.
      View in: PubMed
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