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James F McGinnis

TitleProfessor
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentOphthalmology
Address608 Stanton L Young Blvd
Oklahoma City OK
Phone405/271-3695
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    Collapse Biography 
    Collapse education and training
    State University of New York, Buffalo, NYPhD1970Cellular & Molecular Biology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Cai X, Seal S, McGinnis JF. Non-toxic retention of nanoceria in murine eyes. Mol Vis. 2016; 22:1176-1187. PMID: 27746672.
      View in: PubMed
    2. Cai X, McGinnis JF. Diabetic Retinopathy: Animal Models, Therapies, and Perspectives. J Diabetes Res. 2016; 2016:3789217. PMID: 26881246; PMCID: PMC4736804.
    3. Cai X, McGinnis JF. Nanoceria: a Potential Therapeutic for Dry AMD. Adv Exp Med Biol. 2016; 854:111-8. PMID: 26427401.
      View in: PubMed
    4. Cai X, Chen L, McGinnis JF. Correlation of ER stress and retinal degeneration in tubby mice. Exp Eye Res. 2015 Nov; 140:130-138. PMID: 26325328; PMCID: PMC4624508 [Available on 11/01/16].
    5. Wong LL, Pye QN, Chen L, Seal S, McGinnis JF. Defining the catalytic activity of nanoceria in the P23H-1 rat, a photoreceptor degeneration model. PLoS One. 2015; 10(3):e0121977. PMID: 25822196; PMCID: PMC4379093.
    6. Walkey C, Das S, Seal S, Erlichman J, Heckman K, Ghibelli L, Traversa E, McGinnis JF, Self WT. Catalytic Properties and Biomedical Applications of Cerium Oxide Nanoparticles. Environ Sci Nano. 2015 Feb 01; 2(1):33-53. PMID: 26207185.
      View in: PubMed
    7. Cai X, Yodoi J, Seal S, McGinnis JF. Nanoceria and thioredoxin regulate a common antioxidative gene network in tubby mice. Adv Exp Med Biol. 2014; 801:829-36. PMID: 24664777.
      View in: PubMed
    8. Klump KE, McGinnis JF. The role of reactive oxygen species in ocular malignancy. Adv Exp Med Biol. 2014; 801:655-9. PMID: 24664755.
      View in: PubMed
    9. Wong LL, McGinnis JF. Nanoceria as bona fide catalytic antioxidants in medicine: what we know and what we want to know…. Adv Exp Med Biol. 2014; 801:821-8. PMID: 24664776.
      View in: PubMed
    10. Cai X, Seal S, McGinnis JF. Sustained inhibition of neovascularization in vldlr-/- mice following intravitreal injection of cerium oxide nanoparticles and the role of the ASK1-P38/JNK-NF-?B pathway. Biomaterials. 2014 Jan; 35(1):249-58. PMID: 24140045; PMCID: PMC3911773.
    11. Das S, Dowding JM, Klump KE, McGinnis JF, Self W, Seal S. Cerium oxide nanoparticles: applications and prospects in nanomedicine. Nanomedicine (Lond). 2013 Sep; 8(9):1483-508. PMID: 23987111.
      View in: PubMed
    12. Kyosseva SV, Chen L, Seal S, McGinnis JF. Nanoceria inhibit expression of genes associated with inflammation and angiogenesis in the retina of Vldlr null mice. Exp Eye Res. 2013 Nov; 116:63-74. PMID: 23978600; PMCID: PMC4263290.
    13. Wong LL, Hirst SM, Pye QN, Reilly CM, Seal S, McGinnis JF. Catalytic nanoceria are preferentially retained in the rat retina and are not cytotoxic after intravitreal injection. PLoS One. 2013; 8(3):e58431. PMID: 23536794; PMCID: PMC3594235.
    14. Sun X, Haley J, Bulgakov OV, Cai X, McGinnis J, Li T. Tubby is required for trafficking G protein-coupled receptors to neuronal cilia. Cilia. 2012 Nov 01; 1(1):21. PMID: 23351594; PMCID: PMC3599646.
    15. Cai X, Sezate SA, Seal S, McGinnis JF. Sustained protection against photoreceptor degeneration in tubby mice by intravitreal injection of nanoceria. Biomaterials. 2012 Dec; 33(34):8771-81. PMID: 22959465; PMCID: PMC4176881.
    16. Cai X, Sezate SA, Seal S, McGinnis JF. WITHDRAWN: Sustained protection against photoreceptor degeneration in tubby mice by intravitreal injection of nanoceria. Biomaterials. 2012 Aug 05. PMID: 22871422.
      View in: PubMed
    17. Cai X, McGinnis JF. Oxidative stress: the achilles' heel of neurodegenerative diseases of the retina. Front Biosci (Landmark Ed). 2012 Jan 01; 17:1976-95. PMID: 22201850.
      View in: PubMed
    18. Cai X, Sezate SA, McGinnis JF. Neovascularization: ocular diseases, animal models and therapies. Adv Exp Med Biol. 2012; 723:245-52. PMID: 22183339.
      View in: PubMed
    19. Kong L, Cai X, Zhou X, Wong LL, Karakoti AS, Seal S, McGinnis JF. Nanoceria extend photoreceptor cell lifespan in tubby mice by modulation of apoptosis/survival signaling pathways. Neurobiol Dis. 2011 Jun; 42(3):514-23. PMID: 21396448; PMCID: PMC3411120.
    20. Zhou X, Wong LL, Karakoti AS, Seal S, McGinnis JF. Nanoceria inhibit the development and promote the regression of pathologic retinal neovascularization in the Vldlr knockout mouse. PLoS One. 2011 Feb 22; 6(2):e16733. PMID: 21364932; PMCID: PMC3043063.
    21. Kong L, Zhou X, Li F, Yodoi J, McGinnis J, Cao W. Neuroprotective effect of overexpression of thioredoxin on photoreceptor degeneration in Tubby mice. Neurobiol Dis. 2010 Jun; 38(3):446-55. PMID: 20298786; PMCID: PMC2919840.
    22. Kong L, Chen GD, Zhou X, McGinnis JF, Li F, Cao W. Molecular mechanisms underlying cochlear degeneration in the tubby mouse and the therapeutic effect of sulforaphane. Neurochem Int. 2009 Mar-Apr; 54(3-4):172-9. PMID: 19114066; PMCID: PMC2689618.
    23. Chen J, Patil S, Seal S, McGinnis JF. Nanoceria particles prevent ROI-induced blindness. Adv Exp Med Biol. 2008; 613:53-9. PMID: 18188928.
      View in: PubMed
    24. Chen J, Wu M, Sezate SA, Matsumoto H, Ramsey M, McGinnis JF. Interaction of glyceraldehyde-3-phosphate dehydrogenase in the light-induced rod alpha-transducin translocation. J Neurochem. 2008 Mar; 104(5):1280-92. PMID: 18028335.
      View in: PubMed
    25. Chen J, Wu M, Sezate SA, McGinnis JF. Light threshold-controlled cone alpha-transducin translocation. Invest Ophthalmol Vis Sci. 2007 Jul; 48(7):3350-5. PMID: 17591908.
      View in: PubMed
    26. Kong L, Tanito M, Huang Z, Li F, Zhou X, Zaharia A, Yodoi J, McGinnis JF, Cao W. Delay of photoreceptor degeneration in tubby mouse by sulforaphane. J Neurochem. 2007 May; 101(4):1041-52. PMID: 17394579.
      View in: PubMed
    27. Chen J, Patil S, Seal S, McGinnis JF. Rare earth nanoparticles prevent retinal degeneration induced by intracellular peroxides. Nat Nanotechnol. 2006 Nov; 1(2):142-50. PMID: 18654167.
      View in: PubMed
    28. Gilmour MA, Cardenas MR, Blaik MA, Bahr RJ, McGinnis JF. Evaluation of a comparative pathogenesis between cancer-associated retinopathy in humans and sudden acquired retinal degeneration syndrome in dogs via diagnostic imaging and western blot analysis. Am J Vet Res. 2006 May; 67(5):877-81. PMID: 16649924.
      View in: PubMed
    29. Kong L, Li F, Soleman CE, Li S, Elias RV, Zhou X, Lewis DA, McGinnis JF, Cao W. Bright cyclic light accelerates photoreceptor cell degeneration in tubby mice. Neurobiol Dis. 2006 Mar; 21(3):468-77. PMID: 16216520.
      View in: PubMed
    30. Sampath AP, Strissel KJ, Elias R, Arshavsky VY, McGinnis JF, Chen J, Kawamura S, Rieke F, Hurley JB. Recoverin improves rod-mediated vision by enhancing signal transmission in the mouse retina. Neuron. 2005 May 05; 46(3):413-20. PMID: 15882641.
      View in: PubMed
    31. Elias RV, Sezate SS, Cao W, McGinnis JF. Temporal kinetics of the light/dark translocation and compartmentation of arrestin and alpha-transducin in mouse photoreceptor cells. Mol Vis. 2004 Sep 15; 10:672-81. PMID: 15467522.
      View in: PubMed
    32. Yu X, Rajala RV, McGinnis JF, Li F, Anderson RE, Yan X, Li S, Elias RV, Knapp RR, Zhou X, Cao W. Involvement of insulin/phosphoinositide 3-kinase/Akt signal pathway in 17 beta-estradiol-mediated neuroprotection. J Biol Chem. 2004 Mar 26; 279(13):13086-94. PMID: 14711819.
      View in: PubMed
    33. Cao W, Rajala RV, Li F, Anderson RE, Wei N, Soliman CE, McGinnis JF. Neuroprotective effect of estrogen upon retinal neurons in vitro. Adv Exp Med Biol. 2003; 533:395-402. PMID: 15180290.
      View in: PubMed
    34. McGinnis JF, Matsumoto B, Whelan JP, Cao W. Cytoskeleton participation in subcellular trafficking of signal transduction proteins in rod photoreceptor cells. J Neurosci Res. 2002 Feb 01; 67(3):290-7. PMID: 11813233.
      View in: PubMed
    35. McGinnis JF, Stepanik PL, Chen W, Elias R, Cao W, Lerious V. Unique retina cell phenotypes revealed by immunological analysis of recoverin expression in rat retina cells. J Neurosci Res. 1999 Jan 15; 55(2):252-60. PMID: 9972828.
      View in: PubMed
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