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Wei R Chen

TitleProfessor
InstitutionUniversity of Central Oklahoma
DepartmentEngineering and Physics
AddressBox 177
Edmond OK
Phone405/974-2481
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    Collapse Biography 
    Collapse education and training
    University of Oregon, Eugene, ORMS1984Physics
    University of Oregon, Eugene, ORPhD1988Physics
    University of Oregon, Eugene, ORPostdoc1989Physics

    Collapse Research 
    Collapse research activities and funding
    R01CA205348     (CHEN, WEI R.)Aug 4, 2017 - Jul 31, 2022
    NIH
    Mechanistic study on synergistic photo-immunological effects of laser immunotherapy for metastatic cancers
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Luo M, Shi L, Zhang F, Zhou F, Zhang L, Wang B, Wang P, Zhang Y, Zhang H, Yang D, Zhang G, Chen WR, Wang X. Laser immunotherapy for cutaneous squamous cell carcinoma with optimal thermal effects to enhance tumour immunogenicity. Int J Hyperthermia. 2018 Apr 16; 1-14. PMID: 29482392.
      View in: PubMed
    2. Zhang F, Shi L, Liu P, Zhang L, Wu Q, Wang B, Zhang G, Wang P, Zhou F, Chen WR, Wang X. A novel cosmetic and clinically practicable laser immunotherapy for facial verruca plana: Intense pulsed light combined with BCG-PSN. Photodiagnosis Photodyn Ther. 2018 Jun; 22:86-90. PMID: 29414736.
      View in: PubMed
    3. Liu S, Doughty A, West C, Tang Z, Zhou F, Chen WR. Determination of temperature distribution in tissue for interstitial cancer photothermal therapy. Int J Hyperthermia. 2017 Sep 06; 1-8. PMID: 28826269.
      View in: PubMed
    4. Chiu HY, Leu JD, Chang CY, Lee YJ, Chen WR. Combination of Radiofrequency Ablation and Glycated Chitosan as Treatment on a Syngeneic Breast Tumor Model. Anticancer Res. 2017 06; 37(6):2965-2974. PMID: 28551634.
      View in: PubMed
    5. Li M, Shi L, Luo M, Chen J, Wang B, Zhang F, Keyal U, Bhatta AK, Chen WR, Wang X. Successful treatment of Rosai-Dorfman disease using in situ photoimmunotherapy. Indian J Dermatol Venereol Leprol. 2017 May-Jun; 83(3):332-336. PMID: 28366926.
      View in: PubMed
    6. Naylor MF, Zhou F, Geister BV, Nordquist RE, Li X, Chen WR. Treatment of advanced melanoma with laser immunotherapy and ipilimumab. J Biophotonics. 2017 May; 10(5):618-622. PMID: 28417565.
      View in: PubMed
    7. El-Hussein A, Lam SSK, Raker J, Chen WR, Hamblin MR. N-dihydrogalactochitosan as a potent immune activator for dendritic cells. J Biomed Mater Res A. 2017 04; 105(4):963-972. PMID: 28028922.
      View in: PubMed
    8. Chen DJ, Li XS, Zhao H, Fu Y, Kang HR, Yao FF, Hu J, Qi N, Zhang HH, Du N, Chen WR. Dinitrophenyl hapten with laser immunotherapy for advanced malignant melanoma: A clinical study. Oncol Lett. 2017 Mar; 13(3):1425-1431. PMID: 28454272.
      View in: PubMed
    9. Shi L, Luo M, Chen WR, Hu C, Zhang G, Zhang F, Chen J, Mo X, Cai Q, Yang L, Wang X. In situ photoimmunotherapy for cutaneous granuloma caused by itraconazole-resistant Candida guilliermondii. Dermatol Ther. 2016 Sep; 29(5):353-357. PMID: 27328828.
      View in: PubMed
    10. Wang X, Ji J, Zhang H, Fan Z, Zhang L, Shi L, Zhou F, Chen WR, Wang H, Wang X. Stimulation of dendritic cells by DAMPs in ALA-PDT treated SCC tumor cells. Oncotarget. 2015 Dec 29; 6(42):44688-702. PMID: 26625309; PMCID: PMC4792585.
    11. Ji J, Zhang Y, Chen WR, Wang X. DC vaccine generated by ALA-PDT-induced immunogenic apoptotic cells for skin squamous cell carcinoma. Oncoimmunology. 2016 Jun; 5(6):e1072674. PMID: 27471605; PMCID: PMC4938317.
    12. Ji J, Fan Z, Zhou F, Wang X, Shi L, Zhang H, Wang P, Yang D, Zhang L, Chen WR, Wang X. Improvement of DC vaccine with ALA-PDT induced immunogenic apoptotic cells for skin squamous cell carcinoma. Oncotarget. 2015 Jul 10; 6(19):17135-46. PMID: 25915530; PMCID: PMC4627297.
    13. Lam SS, Zhou F, Hode T, Nordquist RE, Alleruzzo L, Raker J, Chen WR. Advances in strategies and methodologies in cancer immunotherapy. Discov Med. 2015 Apr; 19(105):293-301. PMID: 25977192.
      View in: PubMed
    14. Li Z, Chen H, Zhou F, Li H, Chen WR. Interstitial photoacoustic sensor for the measurement of tissue temperature during interstitial laser phototherapy. Sensors (Basel). 2015 Mar 06; 15(3):5583-93. PMID: 25756865; PMCID: PMC4435156.
    15. Zhou F, Li X, Naylor MF, Hode T, Nordquist RE, Alleruzzo L, Raker J, Lam SS, Du N, Shi L, Wang X, Chen WR. InCVAX--a novel strategy for treatment of late-stage, metastatic cancers through photoimmunotherapy induced tumor-specific immunity. Cancer Lett. 2015 Apr 10; 359(2):169-77. PMID: 25633839; PMCID: PMC4336834.
    16. Li Z, Chen H, Li H, Chen WR. Optical properties of tissues quantified using morphological granulometry from phase-contrast images of thin tissue samples. J Xray Sci Technol. 2015; 23(1):111-8. PMID: 25567411.
      View in: PubMed
    17. Wang X, Lu C, He X, Hu S, Sun A, Hu M, Chen WR. WITHDRAWN: CIB1 acts as a partner protein of CD38 in cADPR synthesis. Biochem Biophys Res Commun. 2014 Jun 23. PMID: 24967876.
      View in: PubMed
    18. Piao D, Towner RA, Smith N, Chen WR. Magnetothermoacoustics from magnetic nanoparticles by short bursting or frequency chirped alternating magnetic field: a theoretical feasibility analysis. Med Phys. 2013 Jun; 40(6):063301. PMID: 23718611; PMCID: PMC3669145.
    19. Qiu Y, Chen X, Li Y, Chen WR, Zheng B, Li S, Liu H. Evaluations of auto-focusing methods under a microscopic imaging modality for metaphase chromosome image analysis. Anal Cell Pathol (Amst). 2013; 36(1-2):37-44. PMID: 23629477; PMCID: PMC3748595.
    20. Qiu Y, Chen X, Li Y, Zheng B, Li S, Chen WR, Liu H. Impact of the optical depth of field on cytogenetic image quality. J Biomed Opt. 2012 Sep; 17(9):96017-1. PMID: 23085918; PMCID: PMC3444261.
    21. Le K, Li X, Figueroa D, Towner RA, Garteiser P, Saunders D, Smith N, Liu H, Hode T, Nordquist RE, Chen WR. Assessment of thermal effects of interstitial laser phototherapy on mammary tumors using proton resonance frequency method. J Biomed Opt. 2011 Dec; 16(12):128001. PMID: 22191937; PMCID: PMC3245746.
    22. Wang X, Zheng B, Li S, Zhang R, Mulvihill JJ, Chen WR, Liu H. Automated detection and analysis of fluorescent in situ hybridization spots depicted in digital microscopic images of Pap-smear specimens. J Biomed Opt. 2009 Mar-Apr; 14(2):021002. PMID: 19405715.
      View in: PubMed
    23. Chen Y, Gnyawali SC, Wu F, Liu H, Tesiram YA, Abbott A, Towner RA, Chen WR. Magnetic resonance imaging guidance for laser photothermal therapy. J Biomed Opt. 2008 Jul-Aug; 13(4):044033. PMID: 19021360.
      View in: PubMed
    24. Gnyawali SC, Chen Y, Wu F, Bartels KE, Wicksted JP, Liu H, Sen CK, Chen WR. Temperature measurement on tissue surface during laser irradiation. Med Biol Eng Comput. 2008 Feb; 46(2):159-68. PMID: 17891430.
      View in: PubMed
    25. Wang X, Li S, Liu H, Wood M, Chen WR, Zheng B. Automated identification of analyzable metaphase chromosomes depicted on microscopic digital images. J Biomed Inform. 2008 Apr; 41(2):264-71. PMID: 17681496; PMCID: PMC2440955.
    26. Zhang D, Rong J, Chen WR, Gao F, Xu K, Wu X, Liu H. Impact of additive noise on system performance of a digital X-ray imaging system. IEEE Trans Biomed Eng. 2007 Jan; 54(1):69-73. PMID: 17260857.
      View in: PubMed
    27. Chen WR, Huang Z. Biophotonics and immune responses-Highlights from a new SPIE photonics west conference (BIOS 2006). Photodiagnosis Photodyn Ther. 2006 Sep; 3(3):184-9. PMID: 25049153.
      View in: PubMed
    28. Crochet JJ, Gnyawali SC, Chen Y, Lemley EC, Wang LV, Chen WR. Temperature distribution in selective laser-tissue interaction. J Biomed Opt. 2006 May-Jun; 11(3):34031. PMID: 16822080.
      View in: PubMed
    29. Zhang Q, Rong J, Wu X, Li Y, Chen WR, Liu H. Impacts of Filtration on Contrast-Detail Detectability of an X-ray Imaging System. Int J Biomed Imaging. 2006; 2006:95754. PMID: 23165063; PMCID: PMC2324059.
    30. Chen WR, Huang Z, Korbelik M, Nordquist RE, Liu H. Photoimmunotherapy for cancer treatment. J Environ Pathol Toxicol Oncol. 2006; 25(1-2):281-91. PMID: 16566724.
      View in: PubMed
    31. Tang D, Li Y, Wong J, Po S, Patterson E, Chen WR, Jackman W, Liu H. Characteristics of a charged-coupled-device-based optical mapping system for the study of cardiac arrhythmias. J Biomed Opt. 2005 Mar-Apr; 10(2):024009. PMID: 15910083.
      View in: PubMed
    32. Chen WR, Korbelik M, Bartels KE, Liu H, Sun J, Nordquist RE. Enhancement of laser cancer treatment by a chitosan-derived immunoadjuvant. Photochem Photobiol. 2005 Jan-Feb; 81(1):190-5. PMID: 15535737.
      View in: PubMed
    33. Bailey CA, Cowan TM, Liu VG, Lemley EC, Chen WR. Optimization of selective hyperthermia. J Biomed Opt. 2004 May-Jun; 9(3):648-54. PMID: 15189104.
      View in: PubMed
    34. Chen WR, Jeong SW, Lucroy MD, Wolf RF, Howard EW, Liu H, Nordquist RE. Induced antitumor immunity against DMBA-4 metastatic mammary tumors in rats using laser immunotherapy. Int J Cancer. 2003 Dec 20; 107(6):1053-7. PMID: 14601069.
      View in: PubMed
    35. Chen WR, Carubelli R, Liu H, Nordquist RE. Detection of anti-tumor immunity induced by laser immunotherapy. Mol Biotechnol. 2003 Sep; 25(1):45-52. PMID: 13679634.
      View in: PubMed
    36. Chen WR, Carubelli R, Liu H, Nordquist RE. Laser immunotherapy: a novel treatment modality for metastatic tumors. Mol Biotechnol. 2003 Sep; 25(1):37-44. PMID: 13679633.
      View in: PubMed
    37. Ishmael DR, Chen WR, Nordquist JA, Liu H, Nordquist RE. Synergistic effect of sequential administration of mitoguazone (MGBG) and gemcitabine in treating tissue cultured human breast cancer cells and mammary rat tumors. Cancer Invest. 2003 Apr; 21(2):217-26. PMID: 12743987.
      View in: PubMed
    38. Ishmael DR, Chen WR, Hamilton SA, Liu H, Nordquist RE. A phase I human trial of mitoguazone and gemcitabine sequential bi-weekly treatment of cancer patients. Cancer Invest. 2003; 21(4):542-9. PMID: 14533444.
      View in: PubMed
    39. Jiang H, Chen WR, Liu H. Techniques to improve the accuracy and to reduce the variance in noise power spectrum measurement. IEEE Trans Biomed Eng. 2002 Nov; 49(11):1270-8. PMID: 12450357.
      View in: PubMed
    40. Chen WR, Liu H, Ritchey JW, Bartels KE, Lucroy MD, Nordquist RE. Effect of different components of laser immunotherapy in treatment of metastatic tumors in rats. Cancer Res. 2002 Aug 01; 62(15):4295-9. PMID: 12154032.
      View in: PubMed
    41. Ouandji F, Potter E, Chen WR, Li Y, Tang D, Liu H. Characterization of a CCD-based digital x-ray imaging system for small-animal studies: properties of spatial resolution. Appl Opt. 2002 May 01; 41(13):2420-7. PMID: 12009151.
      View in: PubMed
    42. Li Y, Chen WR, Zhang Y, Qian W, Liu H. Comparison of analog and digital Fourier transforms in medical image analysis. J Biomed Opt. 2002 Apr; 7(2):255-61. PMID: 11966312.
      View in: PubMed
    43. Lucroy MD, Chen WR, Ridgway TD, Higbee RG, Bartels KE. Selective laser-induced hyperthermia for the treatment of spontaneous tumors in dogs. J Xray Sci Technol. 2002 Jan 01; 10(3):237-43. PMID: 22388052.
      View in: PubMed
    44. Chen WR, Liu H, Carubelli R, Nordquist RE. Synergistic effect of photothermal and photoimmunological reactions in treatment of metastatic tumors. J Xray Sci Technol. 2002 Jan 01; 10(3):225-35. PMID: 22388051.
      View in: PubMed
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