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Stromal Interaction Molecules

"Stromal Interaction Molecules" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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Membrane-associated calcium-binding proteins that are characterized by N-terminal EF HAND MOTIFS and a STERILE ALPHA MOTIF. They function as sensors of ENDOPLASMIC RETICULUM calcium levels and translocate from the ER to the plasma membrane to activate CALCIUM CHANNELS in response to intracellular calcium depletion.


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