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Fertilins

"Fertilins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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Sperm surface proteins involved in sperm-egg fusion. They consist of two subunits, fertilin alpha (ADAM1a) and beta (ADAM2), both of which belong to the metalloprotease-disintegrin protein family. The beta subunit does not have catalytic activity.


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