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William N Green

TitleResident
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentDiagnostic Radiology Residency
Phone405/271-8001
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    Collapse Research 
    Collapse research activities and funding
    R01DA044760     (GREEN, WILLIAM)Jul 1, 2017 - Apr 30, 2022
    NIH/NIDA
    PET imaging of a4b2 nicotinic receptor upregulation and smoking cessation
    Role: Principal Investigator

    R01NS100019     (SELVIN, PAUL R)Jul 1, 2017 - Jun 30, 2021
    NIH/NINDS
    Super-Resolution Microscopy of Neuronal Synapses with Small Quantum Dots and Advanced Imaging Tools
    Role: Co-Principal Investigator

    R56NS090903     (SELVIN, PAUL R)Sep 30, 2014 - Sep 29, 2015
    NIH/NINDS
    Organization and Dynamics of PSD-bound Glutamate Receptors at Super-resolution
    Role: Co-Principal Investigator

    R01DA035430     (GREEN, WILLIAM)Aug 1, 2013 - Apr 30, 2018
    NIH/NIDA
    Different components of nicotine-induced upregulation of nicotinic receptors
    Role: Principal Investigator

    R21MH081251     (GREEN, WILLIAM NATHAN)Dec 4, 2009 - Nov 30, 2011
    NIH/NIMH
    Proteomic Assays of Neuronal Protein Palmitoylation
    Role: Principal Investigator

    R13DK063646     (GREEN, WILLIAM N.)Sep 3, 2002 - Aug 31, 2003
    NIH/NIDDK
    Trafficking of Transporters
    Role: Principal Investigator

    R01NS043782     (GREEN, WILLIAM NATHAN)Apr 1, 2002 - Jul 31, 2013
    NIH/NINDS
    The Neuronal alpha-bungarotoxin Binding Site
    Role: Principal Investigator

    R56NS043782     (GREEN, WILLIAM N.)Apr 1, 2002 - Jul 31, 2009
    NIH/NINDS
    The Neuronal alpha-bungarotoxin Binding Site
    Role: Principal Investigator

    R01DA013602     (GREEN, WILLIAM N.)Aug 1, 2001 - May 31, 2007
    NIH/NIDA
    UPREGULATION OF NICOTINIC RECEPTORS
    Role: Principal Investigator

    R01NS032693     (GREEN, WILLIAM N.)Aug 1, 1997 - Mar 31, 2007
    NIH/NINDS
    Quality Control of Nicotinic Receptor Assembly
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hong X, Jeyifous O, Ronilo M, Marshall J, Green WN, Standley S. A novel function for the ER retention signals in the C-terminus of kainate receptor subunit, GluK5. Biochim Biophys Acta Mol Cell Res. 2019 03; 1866(3):459-473. PMID: 30339823.
      View in: PubMed
    2. Samra GK, Intskirveli I, Govind AP, Liang C, Lazar R, Green WN, Metherate R, Mukherjee J. Development of fluorescence imaging probes for nicotinic acetylcholine a4ß2* receptors. Bioorg Med Chem Lett. 2018 02 01; 28(3):371-377. PMID: 29277457.
      View in: PubMed
    3. Lee SH, Jin C, Cai E, Ge P, Ishitsuka Y, Teng KW, de Thomaz AA, Nall D, Baday M, Jeyifous O, Demonte D, Dundas CM, Park S, Delgado JY, Green WN, Selvin PR. Correction: Super-resolution imaging of synaptic and Extra-synaptic AMPA receptors with different-sized fluorescent probes. Elife. 2017 11 08; 6. PMID: 29116041.
      View in: PubMed
    4. Lee SH, Jin C, Cai E, Ge P, Ishitsuka Y, Teng KW, de Thomaz AA, Nall D, Baday M, Jeyifous O, Demonte D, Dundas CM, Park S, Delgado JY, Green WN, Selvin PR. Super-resolution imaging of synaptic and Extra-synaptic AMPA receptors with different-sized fluorescent probes. Elife. 2017 07 27; 6. PMID: 28749340.
      View in: PubMed
    5. Govind AP, Vallejo YF, Stolz JR, Yan JZ, Swanson GT, Green WN. Selective and regulated trapping of nicotinic receptor weak base ligands and relevance to smoking cessation. Elife. 2017 07 18; 6. PMID: 28718768.
      View in: PubMed
    6. Antinone SE, Ghadge GD, Ostrow LW, Roos RP, Green WN. S-acylation of SOD1, CCS, and a stable SOD1-CCS heterodimer in human spinal cords from ALS and non-ALS subjects. Sci Rep. 2017 01 25; 7:41141. PMID: 28120938.
      View in: PubMed
    7. Jeyifous O, Lin EI, Chen X, Antinone SE, Mastro R, Drisdel R, Reese TS, Green WN. Palmitoylation regulates glutamate receptor distributions in postsynaptic densities through control of PSD95 conformation and orientation. Proc Natl Acad Sci U S A. 2016 12 27; 113(52):E8482-E8491. PMID: 27956638.
      View in: PubMed
    8. Zheng N, Jeyifous O, Munro C, Montgomery JM, Green WN. Synaptic activity regulates AMPA receptor trafficking through different recycling pathways. Elife. 2015 May 13; 4. PMID: 25970033.
      View in: PubMed
    9. Wang Y, Cai E, Rosenkranz T, Ge P, Teng KW, Lim SJ, Smith AM, Chung HJ, Sachs F, Green WN, Gottlieb P, Selvin PR. Small quantum dots conjugated to nanobodies as immunofluorescence probes for nanometric microscopy. Bioconjug Chem. 2014 Dec 17; 25(12):2205-11. PMID: 25397889.
      View in: PubMed
    10. Cai E, Ge P, Lee SH, Jeyifous O, Wang Y, Liu Y, Wilson KM, Lim SJ, Baird MA, Stone JE, Lee KY, Davidson MW, Chung HJ, Schulten K, Smith AM, Green WN, Selvin PR. Stable small quantum dots for synaptic receptor tracking on live neurons. Angew Chem Int Ed Engl. 2014 Nov 10; 53(46):12484-8. PMID: 25255882.
      View in: PubMed
    11. Cortes CJ, Qin K, Norstrom EM, Green WN, Bindokas VP, Mastrianni JA. Early Delivery of Misfolded PrP from ER to Lysosomes by Autophagy. Int J Cell Biol. 2013; 2013:560421. PMID: 24454378.
      View in: PubMed
    12. Lin EI, Jeyifous O, Green WN. CASK regulates SAP97 conformation and its interactions with AMPA and NMDA receptors. J Neurosci. 2013 Jul 17; 33(29):12067-76. PMID: 23864692.
      View in: PubMed
    13. Antinone SE, Ghadge GD, Lam TT, Wang L, Roos RP, Green WN. Palmitoylation of superoxide dismutase 1 (SOD1) is increased for familial amyotrophic lateral sclerosis-linked SOD1 mutants. J Biol Chem. 2013 Jul 26; 288(30):21606-17. PMID: 23760509.
      View in: PubMed
    14. Baker LK, Mao D, Chi H, Govind AP, Vallejo YF, Iacoviello M, Herrera S, Cortright JJ, Green WN, McGehee DS, Vezina P. Intermittent nicotine exposure upregulates nAChRs in VTA dopamine neurons and sensitises locomotor responding to the drug. Eur J Neurosci. 2013 Mar; 37(6):1004-11. PMID: 23331514.
      View in: PubMed
    15. Govind AP, Walsh H, Green WN. Nicotine-induced upregulation of native neuronal nicotinic receptors is caused by multiple mechanisms. J Neurosci. 2012 Feb 08; 32(6):2227-38. PMID: 22323734.
      View in: PubMed
    16. Singaraja RR, Huang K, Sanders SS, Milnerwood AJ, Hines R, Lerch JP, Franciosi S, Drisdel RC, Vaid K, Young FB, Doty C, Wan J, Bissada N, Henkelman RM, Green WN, Davis NG, Raymond LA, Hayden MR. Altered palmitoylation and neuropathological deficits in mice lacking HIP14. Hum Mol Genet. 2011 Oct 15; 20(20):3899-909. PMID: 21775500.
      View in: PubMed
    17. Simonson PD, Deberg HA, Ge P, Alexander JK, Jeyifous O, Green WN, Selvin PR. Counting bungarotoxin binding sites of nicotinic acetylcholine receptors in mammalian cells with high signal/noise ratios. Biophys J. 2010 Nov 17; 99(10):L81-3. PMID: 21081055.
      View in: PubMed
    18. Alexander JK, Sagher D, Krivoshein AV, Criado M, Jefford G, Green WN. Ric-3 promotes alpha7 nicotinic receptor assembly and trafficking through the ER subcompartment of dendrites. J Neurosci. 2010 Jul 28; 30(30):10112-26. PMID: 20668195.
      View in: PubMed
    19. Jeyifous O, Waites CL, Specht CG, Fujisawa S, Schubert M, Lin EI, Marshall J, Aoki C, de Silva T, Montgomery JM, Garner CC, Green WN. SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway. Nat Neurosci. 2009 Aug; 12(8):1011-9. PMID: 19620977.
      View in: PubMed
    20. Singaraja RR, Kang MH, Vaid K, Sanders SS, Vilas GL, Arstikaitis P, Coutinho J, Drisdel RC, El-Husseini Ael D, Green WN, Berthiaume L, Hayden MR. Palmitoylation of ATP-binding cassette transporter A1 is essential for its trafficking and function. Circ Res. 2009 Jul 17; 105(2):138-47. PMID: 19556522.
      View in: PubMed
    21. Govind AP, Vezina P, Green WN. Nicotine-induced upregulation of nicotinic receptors: underlying mechanisms and relevance to nicotine addiction. Biochem Pharmacol. 2009 Oct 01; 78(7):756-65. PMID: 19540212.
      View in: PubMed
    22. Waites CL, Specht CG, Härtel K, Leal-Ortiz S, Genoux D, Li D, Drisdel RC, Jeyifous O, Cheyne JE, Green WN, Montgomery JM, Garner CC. Synaptic SAP97 isoforms regulate AMPA receptor dynamics and access to presynaptic glutamate. J Neurosci. 2009 Apr 08; 29(14):4332-45. PMID: 19357261.
      View in: PubMed
    23. Kang R, Wan J, Arstikaitis P, Takahashi H, Huang K, Bailey AO, Thompson JX, Roth AF, Drisdel RC, Mastro R, Green WN, Yates JR, Davis NG, El-Husseini A. Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation. Nature. 2008 Dec 18; 456(7224):904-9. PMID: 19092927.
      View in: PubMed
    24. Cheng H, Vetrivel KS, Drisdel RC, Meckler X, Gong P, Leem JY, Li T, Carter M, Chen Y, Nguyen P, Iwatsubo T, Tomita T, Wong PC, Green WN, Kounnas MZ, Thinakaran G. S-palmitoylation of gamma-secretase subunits nicastrin and APH-1. J Biol Chem. 2009 Jan 16; 284(3):1373-84. PMID: 19028695.
      View in: PubMed
    25. Liu Y, Padgett D, Takahashi M, Li H, Sayeed A, Teichert RW, Olivera BM, McArdle JJ, Green WN, Lin W. Essential roles of the acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning. Development. 2008 Jun; 135(11):1957-67. PMID: 18434415.
      View in: PubMed
    26. Walsh H, Govind AP, Mastro R, Hoda JC, Bertrand D, Vallejo Y, Green WN. Up-regulation of nicotinic receptors by nicotine varies with receptor subtype. J Biol Chem. 2008 Mar 07; 283(10):6022-32. PMID: 18174175.
      View in: PubMed
    27. Wanamaker CP, Green WN. Endoplasmic reticulum chaperones stabilize nicotinic receptor subunits and regulate receptor assembly. J Biol Chem. 2007 Oct 26; 282(43):31113-23. PMID: 17728248.
      View in: PubMed
    28. Drisdel RC, Sharp D, Henderson T, Hales TG, Green WN. High affinity binding of epibatidine to serotonin type 3 receptors. J Biol Chem. 2008 Apr 11; 283(15):9659-65. PMID: 17702741.
      View in: PubMed
    29. Drisdel RC, Alexander JK, Sayeed A, Green WN. Assays of protein palmitoylation. Methods. 2006 Oct; 40(2):127-34. PMID: 17012024.
      View in: PubMed
    30. Roth AF, Wan J, Green WN, Yates JR, Davis NG. Proteomic identification of palmitoylated proteins. Methods. 2006 Oct; 40(2):135-42. PMID: 17012025.
      View in: PubMed
    31. Roth AF, Wan J, Bailey AO, Sun B, Kuchar JA, Green WN, Phinney BS, Yates JR, Davis NG. Global analysis of protein palmitoylation in yeast. Cell. 2006 Jun 02; 125(5):1003-13. PMID: 16751107.
      View in: PubMed
    32. Yanai A, Huang K, Kang R, Singaraja RR, Arstikaitis P, Gan L, Orban PC, Mullard A, Cowan CM, Raymond LA, Drisdel RC, Green WN, Ravikumar B, Rubinsztein DC, El-Husseini A, Hayden MR. Palmitoylation of huntingtin by HIP14 is essential for its trafficking and function. Nat Neurosci. 2006 Jun; 9(6):824-31. PMID: 16699508.
      View in: PubMed
    33. Wanamaker CP, Green WN. N-linked glycosylation is required for nicotinic receptor assembly but not for subunit associations with calnexin. J Biol Chem. 2005 Oct 07; 280(40):33800-10. PMID: 16091366.
      View in: PubMed
    34. Vallejo YF, Buisson B, Bertrand D, Green WN. Chronic nicotine exposure upregulates nicotinic receptors by a novel mechanism. J Neurosci. 2005 Jun 08; 25(23):5563-72. PMID: 15944384.
      View in: PubMed
    35. Drisdel RC, Manzana E, Green WN. The role of palmitoylation in functional expression of nicotinic alpha7 receptors. J Neurosci. 2004 Nov 17; 24(46):10502-10. PMID: 15548665.
      View in: PubMed
    36. Christianson JC, Green WN. Regulation of nicotinic receptor expression by the ubiquitin-proteasome system. EMBO J. 2004 Oct 27; 23(21):4156-65. PMID: 15483627.
      View in: PubMed
    37. Drisdel RC, Green WN. Labeling and quantifying sites of protein palmitoylation. Biotechniques. 2004 Feb; 36(2):276-85. PMID: 14989092.
      View in: PubMed
    38. Wanamaker CP, Christianson JC, Green WN. Regulation of nicotinic acetylcholine receptor assembly. Ann N Y Acad Sci. 2003 Sep; 998:66-80. PMID: 14592864.
      View in: PubMed
    39. Kopito RR, Green WN, Andersen O. The 56th Annual Meeting and Symposium of the Society of General Physiologists: trafficking of transporters. J Gen Physiol. 2003 Feb; 121(2):73-9. PMID: 12566536.
      View in: PubMed
    40. Leem JY, Saura CA, Pietrzik C, Christianson J, Wanamaker C, King LT, Veselits ML, Tomita T, Gasparini L, Iwatsubo T, Xu H, Green WN, Koo EH, Thinakaran G. A role for presenilin 1 in regulating the delivery of amyloid precursor protein to the cell surface. Neurobiol Dis. 2002 Oct; 11(1):64-82. PMID: 12460547.
      View in: PubMed
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