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Surface Plasmon Resonance

"Surface Plasmon Resonance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A biosensing technique in which biomolecules capable of binding to specific analytes or ligands are first immobilized on one side of a metallic film. Light is then focused on the opposite side of the film to excite the surface plasmons, that is, the oscillations of free electrons propagating along the film's surface. The refractive index of light reflecting off this surface is measured. When the immobilized biomolecules are bound by their ligands, an alteration in surface plasmons on the opposite side of the film is created which is directly proportional to the change in bound, or adsorbed, mass. Binding is measured by changes in the refractive index. The technique is used to study biomolecular interactions, such as antigen-antibody binding.


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This graph shows the total number of publications written about "Surface Plasmon Resonance" by people in this website by year, and whether "Surface Plasmon Resonance" was a major or minor topic of these publications.
Bar chart showing 27 publications over 13 distinct years, with a maximum of 6 publications in 2009
To see the data from this visualization as text, click here.