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Anne Kasus-Jacobi

TitleAssistant Professor of Research
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentPharmaceutical Sciences
Address1110 N Stonewall Ave
Oklahoma City OK 73117-1200
Phone405/271-1484
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    Collapse Research 
    Collapse research activities and funding
    R21EY018907     (KASUS-JACOBI, ANNE)Sep 30, 2008 - Aug 31, 2011
    NIH/NEI
    Detoxification Role of Retinol Dehydrogenases RDH11 and RDH12
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Griffith GL, Kasus-Jacobi A, Pereira HA. Bioactive Antimicrobial Peptides as Therapeutics for Corneal Wounds and Infections. Adv Wound Care (New Rochelle). 2017 Jun 01; 6(6):175-190. PMID: 28616359.
      View in: PubMed
    2. Stock AJ, Kasus-Jacobi A, Wren JD, Sjoelund VH, Prestwich GD, Pereira HA. The Role of Neutrophil Proteins on the Amyloid Beta-RAGE Axis. PLoS One. 2016; 11(9):e0163330. PMID: 27676391.
      View in: PubMed
    3. Brock AJ, Kasus-Jacobi A, Lerner M, Logan S, Adesina AM, Anne Pereira H. The antimicrobial protein, CAP37, is upregulated in pyramidal neurons during Alzheimer's disease. Histochem Cell Biol. 2015 Oct; 144(4):293-308. PMID: 26170148; PMCID: PMC4575391.
    4. Kasus-Jacobi A, Noor-Mohammadi S, Griffith GL, Hinsley H, Mathias L, Pereira HA. A multifunctional peptide based on the neutrophil immune defense molecule, CAP37, has antibacterial and wound-healing properties. J Leukoc Biol. 2015 Feb; 97(2):341-50. PMID: 25412625; PMCID: PMC4304423.
    5. Griffith GL, Kasus-Jacobi A, Lerner MR, Pereira HA. Corneal wound healing, a newly identified function of CAP37, is mediated by protein kinase C delta (PKCd). Invest Ophthalmol Vis Sci. 2014 Jul 15; 55(8):4886-95. PMID: 25028358; PMCID: PMC4126793.
    6. Babizhayev MA, Kasus-Jacobi A, Vishnyakova KS, Yegorov YE. Novel neuroendocrine and metabolic mechanism provides the patented platform for important rejuvenation therapies: targeted therapy of telomere attrition and lifestyle changes of telomerase activity with the timing of neuron-specific imidazole-containing dipeptide-dominant pharmaconutrition provision. Recent Pat Endocr Metab Immune Drug Discov. 2014; 8(3):153-79. PMID: 24910283.
      View in: PubMed
    7. Griffith GL, Russell RA, Kasus-Jacobi A, Thavathiru E, Gonzalez ML, Logan S, Pereira HA. CAP37 activation of PKC promotes human corneal epithelial cell chemotaxis. Invest Ophthalmol Vis Sci. 2013 Oct 15; 54(10):6712-23. PMID: 24008408; PMCID: PMC3797592.
    8. Marchette LD, Wang H, Li F, Babizhayev MA, Kasus-Jacobi A. Carcinine has 4-hydroxynonenal scavenging property and neuroprotective effect in mouse retina. Invest Ophthalmol Vis Sci. 2012 Jun 20; 53(7):3572-83. PMID: 22577078; PMCID: PMC3390180.
    9. Babizhayev MA, Khoroshilova-Maslova IP, Kasus-Jacobi A. Novel intraocular and systemic absorption drug delivery and efficacy of N-acetylcarnosine lubricant eye drops or carcinine biologics in pharmaceutical usage and therapeutic vision care. Fundam Clin Pharmacol. 2012 Oct; 26(5):644-78. PMID: 21793899.
      View in: PubMed
    10. Mandal MN, Moiseyev GP, Elliott MH, Kasus-Jacobi A, Li X, Chen H, Zheng L, Nikolaeva O, Floyd RA, Ma JX, Anderson RE. Alpha-phenyl-N-tert-butylnitrone (PBN) prevents light-induced degeneration of the retina by inhibiting RPE65 protein isomerohydrolase activity. J Biol Chem. 2011 Sep 16; 286(37):32491-501. PMID: 21785167; PMCID: PMC3173208.
    11. Babizhayev MA, Micans P, Guiotto A, Kasus-Jacobi A. N-acetylcarnosine lubricant eyedrops possess all-in-one universal antioxidant protective effects of L-carnosine in aqueous and lipid membrane environments, aldehyde scavenging, and transglycation activities inherent to cataracts: a clinical study of the new vision-saving drug N-acetylcarnosine eyedrop therapy in a database population of over 50,500 patients. Am J Ther. 2009 Nov-Dec; 16(6):517-33. PMID: 19487926.
      View in: PubMed
    12. Marchette LD, Thompson DA, Kravtsova M, Ngansop TN, Mandal MN, Kasus-Jacobi A. Retinol dehydrogenase 12 detoxifies 4-hydroxynonenal in photoreceptor cells. Free Radic Biol Med. 2010 Jan 01; 48(1):16-25. PMID: 19686838; PMCID: PMC2874966.
    13. Babizhayev MA, Kasus-Jacobi A. State of the art clinical efficacy and safety evaluation of N-acetylcarnosine dipeptide ophthalmic prodrug. Principles for the delivery, self-bioactivation, molecular targets and interaction with a highly evolved histidyl-hydrazide structure in the treatment and therapeutic management of a group of sight-threatening eye diseases. Curr Clin Pharmacol. 2009 Jan; 4(1):4-37. PMID: 19149498.
      View in: PubMed
    14. Babizhayev MA, Guiotto A, Kasus-Jacobi A. N-Acetylcarnosine and histidyl-hydrazide are potent agents for multitargeted ophthalmic therapy of senile cataracts and diabetic ocular complications. J Drug Target. 2009 Jan; 17(1):36-63. PMID: 19037813.
      View in: PubMed
    15. Mandal MN, Patlolla JM, Zheng L, Agbaga MP, Tran JT, Wicker L, Kasus-Jacobi A, Elliott MH, Rao CV, Anderson RE. Curcumin protects retinal cells from light-and oxidant stress-induced cell death. Free Radic Biol Med. 2009 Mar 01; 46(5):672-9. PMID: 19121385; PMCID: PMC2810836.
    16. Kanan Y, Wicker LD, Al-Ubaidi MR, Mandal NA, Kasus-Jacobi A. Retinol dehydrogenases RDH11 and RDH12 in the mouse retina: expression levels during development and regulation by oxidative stress. Invest Ophthalmol Vis Sci. 2008 Mar; 49(3):1071-8. PMID: 18326732; PMCID: PMC2366097.
    17. Kanan Y, Kasus-Jacobi A, Moiseyev G, Sawyer K, Ma JX, Al-Ubaidi MR. Retinoid processing in cone and Müller cell lines. Exp Eye Res. 2008 Feb; 86(2):344-54. PMID: 18163989; PMCID: PMC2947831.
    18. Kasus-Jacobi A, Birch DG, Anderson RE. Photoreceptor retinol dehydrogenases. An attempt to characterize the function of Rdh11. Adv Exp Med Biol. 2006; 572:505-11. PMID: 17249616.
      View in: PubMed
    19. Kasus-Jacobi A, Ou J, Birch DG, Locke KG, Shelton JM, Richardson JA, Murphy AJ, Valenzuela DM, Yancopoulos GD, Edwards AO. Functional characterization of mouse RDH11 as a retinol dehydrogenase involved in dark adaptation in vivo. J Biol Chem. 2005 May 27; 280(21):20413-20. PMID: 15790565.
      View in: PubMed
    20. Cariou B, Bereziat V, Moncoq K, Kasus-Jacobi A, Perdereau D, Le Marcis V, Burnol AF. Regulation and functional roles of Grb14. Front Biosci. 2004 May 01; 9:1626-36. PMID: 14977573.
      View in: PubMed
    21. Kasus-Jacobi A, Ou J, Bashmakov YK, Shelton JM, Richardson JA, Goldstein JL, Brown MS. Characterization of mouse short-chain aldehyde reductase (SCALD), an enzyme regulated by sterol regulatory element-binding proteins. J Biol Chem. 2003 Aug 22; 278(34):32380-9. PMID: 12807874.
      View in: PubMed
    22. Béréziat V, Kasus-Jacobi A, Perdereau D, Cariou B, Girard J, Burnol AF. Inhibition of insulin receptor catalytic activity by the molecular adapter Grb14. J Biol Chem. 2002 Feb 15; 277(7):4845-52. PMID: 11726652.
      View in: PubMed
    23. Kasus-Jacobi A, Béréziat V, Perdereau D, Girard J, Burnol AF. Evidence for an interaction between the insulin receptor and Grb7. A role for two of its binding domains, PIR and SH2. Oncogene. 2000 Apr 13; 19(16):2052-9. PMID: 10803466.
      View in: PubMed
    24. Kasus-Jacobi A, Perdereau D, Auzan C, Clauser E, Van Obberghen E, Mauvais-Jarvis F, Girard J, Burnol AF. Identification of the rat adapter Grb14 as an inhibitor of insulin actions. J Biol Chem. 1998 Oct 02; 273(40):26026-35. PMID: 9748281.
      View in: PubMed
    25. Kasus-Jacobi A, Perdereau D, Tartare-Deckert S, Van Obberghen E, Girard J, Burnol AF. Evidence for a direct interaction between insulin receptor substrate-1 and Shc. J Biol Chem. 1997 Jul 04; 272(27):17166-70. PMID: 9202037.
      View in: PubMed
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