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Anthony W Burgett

TitleAssistant Professor
InstitutionUniversity of Oklahoma, Norman
DepartmentChemistry/Biochemistry
Phone405/325-3551
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    Collapse Biography 
    Collapse education and training
    Harvard University, Cambridge, MAPostdoc2010Molecular Pharmacology
    UT Southwestern Medical Center, Dallas, TXPhD2006Biological Chemistry
    University of Oklahoma, Norman, OKBS1999Microbiology
    University of Oklahoma, Norman, OKBS1999Biochemistry

    Collapse Research 
    Collapse research activities and funding
    R21CA204706     (BURGETT, ANTHONY WG)May 23, 2016 - Apr 30, 2019
    NIH
    Mass Spectrometry Detection of Drugs in Single Bladder Cancer Cells from Patients
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Roberts BL, Severance ZC, Bensen RC, Le AT, Malinky CA, Mettenbrink EM, Nuñez JI, Reddig WJ, Blewett EL, Burgett AWG. Differing activities of oxysterol-binding protein (OSBP) targeting anti-viral compounds. Antiviral Res. 2019 Jul 01; 104548. PMID: 31271764.
      View in: PubMed
    2. Pan N, Standke SJ, Kothapalli NR, Sun M, Bensen RC, Burgett AWG, Yang Z. Quantification of Drug Molecules in Live Single Cells Using the Single-Probe Mass Spectrometry Technique. Anal Chem. 2019 Jul 16; 91(14):9018-9024. PMID: 31246408.
      View in: PubMed
    3. Standke SJ, Colby DH, Bensen RC, Burgett AWG, Yang Z. Integrated Cell Manipulation Platform Coupled with the Single-probe for Mass Spectrometry Analysis of Drugs and Metabolites in Single Suspension Cells. J Vis Exp. 2019 Jun 21; (148). PMID: 31282898.
      View in: PubMed
    4. Standke SJ, Colby DH, Bensen RC, Burgett AWG, Yang Z. Mass Spectrometry Measurement of Single Suspended Cells Using a Combined Cell Manipulation System and a Single-Probe Device. Anal Chem. 2019 Feb 05; 91(3):1738-1742. PMID: 30644722.
      View in: PubMed
    5. Roberts BL, Severance ZC, Bensen RC, Le AT, Kothapalli NR, Nuñez JI, Ma H, Wu S, Standke SJ, Yang Z, Reddig WJ, Blewett EL, Burgett AWG. Transient Compound Treatment Induces a Multigenerational Reduction of Oxysterol-Binding Protein (OSBP) Levels and Prophylactic Antiviral Activity. ACS Chem Biol. 2019 Feb 15; 14(2):276-287. PMID: 30576108.
      View in: PubMed
    6. Harper AR, Le AT, Mather T, Burgett A, Berry W, Summers JA. Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes. Bioorg Med Chem. 2018 12 01; 26(22):5766-5779. PMID: 30409702.
      View in: PubMed
    7. Terzyan SS, Burgett AW, Heroux A, Smith CA, Mooers BH, Hanigan MH. Human ?-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS. J Biol Chem. 2015 Jul 10; 290(28):17576-86. PMID: 26013825.
      View in: PubMed
    8. Pan N, Rao W, Kothapalli NR, Liu R, Burgett AW, Yang Z. The single-probe: a miniaturized multifunctional device for single cell mass spectrometry analysis. Anal Chem. 2014 Oct 07; 86(19):9376-80. PMID: 25222919.
      View in: PubMed
    9. Burgett AW, Poulsen TB, Wangkanont K, Anderson DR, Kikuchi C, Shimada K, Okubo S, Fortner KC, Mimaki Y, Kuroda M, Murphy JP, Schwalb DJ, Petrella EC, Cornella-Taracido I, Schirle M, Tallarico JA, Shair MD. Natural products reveal cancer cell dependence on oxysterol-binding proteins. Nat Chem Biol. 2011 Aug 07; 7(9):639-47. PMID: 21822274.
      View in: PubMed
    10. Williams NS, Burgett AW, Atkins AS, Wang X, Harran PG, McKnight SL. Therapeutic anticancer efficacy of a synthetic diazonamide analog in the absence of overt toxicity. Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7):2074-9. PMID: 17287337.
      View in: PubMed
    11. Wang G, Shang L, Burgett AW, Harran PG, Wang X. Diazonamide toxins reveal an unexpected function for ornithine delta-amino transferase in mitotic cell division. Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7):2068-73. PMID: 17287350.
      View in: PubMed
    12. Burgett AW, Li Q, Wei Q, Harran PG. A concise and flexible total synthesis of (-)-diazonamide A. Angew Chem Int Ed Engl. 2003 Oct 20; 42(40):4961-6. PMID: 14579451.
      View in: PubMed
    13. Li J, Burgett AW, Esser L, Amezcua C, Harran PG. Total Synthesis of Nominal Diazonamides-Part 2: On the True Structure and Origin of Natural Isolates Funding provided by the NIH (RO1-GM60591), the NSF (CAREER 9984282), the Howard Hughes Medical Institute (junior faculty support), the Robert A. Welch Foundation, and the Advanced Research Program of the Texas Higher Education Coordinating Board. We are grateful to Professor Michael Roth for his time, insight, and advice. Angew Chem Int Ed Engl. 2001 Dec 17; 40(24):4770-4773. PMID: 12404412.
      View in: PubMed
    14. Li J, Burgett AW, Esser L, Amezcua C, Harran PG. Preview. Angew Chem Int Ed Engl. 2001 Dec 17; 40(24):4776. PMID: 12404413.
      View in: PubMed
    15. Li J, Chen X, Burgett AWG, Harran PG. Synthetic seco Forms of (-)-Diazonamide A. Angew Chem Int Ed Engl. 2001 Jul 16; 40(14):2682-2685. PMID: 29712335.
      View in: PubMed
    16. Li J, Chen X, Burgett AW, Harran PG. Synthetic seco Forms of (-)-Diazonamide A We thank Prof. Michael Roth for advice and insight and Ms. Susan Jeong for invaluable experimental assistance. Funding was provided by the NIH (RO1-GM60591), the NSF (CAREER 9984282), the Howard Hughes Medical Institute (junior faculty support), and the Robert A. Welch Foundation. Angew Chem Int Ed Engl. 2001 Jul 16; 40(14):2682-2685. PMID: 11458372.
      View in: PubMed
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