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Last Name

K Mark Coggeshall

TitleRobert S. Kerr, Jr. Endowed Chair in Cancer Research
InstitutionOklahoma Medical Research Foundation
DepartmentArthritis and Clinical Immunology
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    Collapse Research 
    Collapse research activities and funding
    R21AI113020     (COGGESHALL, KENNETH MARK)Aug 1, 2014 - Jul 31, 2016
    Development of a mouse model of peptidoglycan-induced pathology
    Role: Principal Investigator

    U19AI062629     (COGGESHALL, KENNETH MARK)Sep 15, 2004 - Aug 31, 2019
    Molecular and Immunologic Analysis of the Pathobiology of Human Anthrax
    Role: Principal Investigator

    R01AI049264     (COGGESHALL, KENNETH MARK)Feb 1, 2002 - Jan 31, 2008
    Signaling by IgG receptors leading to phagocytosis
    Role: Principal Investigator

    R01AI041447     (COGGESHALL, KENNETH MARK)Jul 1, 1997 - Jun 30, 2002
    Role: Principal Investigator

    R01CA064268     (COGGESHALL, KENNETH MARK)Aug 1, 1994 - Aug 31, 2004
    Role: Principal Investigator

    R29CA064268     (COGGESHALL, KENNETH MARK)Aug 1, 1994 - Jul 31, 1999
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wolf AJ, Reyes CN, Liang W, Becker C, Shimada K, Wheeler ML, Cho HC, Popescu NI, Coggeshall KM, Arditi M, Underhill DM. Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan. Cell. 2016 Jul 28; 166(3):624-636. PMID: 27374331.
      View in: PubMed
    2. Booth JL, Duggan ES, Patel VI, Langer M, Wu W, Braun A, Coggeshall KM, Metcalf JP. Bacillus anthracis spore movement does not require a carrier cell and is not affected by lethal toxin in human lung models. Microbes Infect. 2016 Oct; 18(10):615-626. PMID: 27320392.
      View in: PubMed
    3. Maier-Moore JS, Horton CG, Mathews SA, Confer AW, Lawrence C, Pan Z, Coggeshall KM, Farris AD. Interleukin-6 deficiency corrects nephritis, lymphocyte abnormalities, and secondary Sjögren's syndrome features in lupus-prone Sle1.Yaa mice. Arthritis Rheumatol. 2014 Sep; 66(9):2521-31. PMID: 24891301; PMCID: PMC4146640.
    4. Lupu F, Keshari RS, Lambris JD, Coggeshall KM. Crosstalk between the coagulation and complement systems in sepsis. Thromb Res. 2014 May; 133 Suppl 1:S28-31. PMID: 24759136; PMCID: PMC4154483.
    5. An JH, Kurokawa K, Jung DJ, Kim MJ, Kim CH, Fujimoto Y, Fukase K, Coggeshall KM, Lee BL. Human SAP is a novel peptidoglycan recognition protein that induces complement-independent phagocytosis of Staphylococcus aureus. J Immunol. 2013 Sep 15; 191(6):3319-27. PMID: 23966633; PMCID: PMC4277995.
    6. Barua S, Iyer JK, Larabee JL, Raisley B, Hughes MA, Coggeshall KM, Ballard JD. Toxin inhibition of antimicrobial factors induced by Bacillus anthracis peptidoglycan in human blood. Infect Immun. 2013 Oct; 81(10):3693-702. PMID: 23876807; PMCID: PMC3811742.
    7. Coggeshall KM, Lupu F, Ballard J, Metcalf JP, James JA, Farris D, Kurosawa S. The sepsis model: an emerging hypothesis for the lethality of inhalation anthrax. J Cell Mol Med. 2013 Jul; 17(7):914-20. PMID: 23742651; PMCID: PMC3729634.
    8. Sun D, Popescu NI, Raisley B, Keshari RS, Dale GL, Lupu F, Coggeshall KM. Bacillus anthracis peptidoglycan activates human platelets through Fc?RII and complement. Blood. 2013 Jul 25; 122(4):571-9. PMID: 23733338; PMCID: PMC3724192.
    9. Langer M, Duggan ES, Booth JL, Patel VI, Zander RA, Silasi-Mansat R, Ramani V, Veres TZ, Prenzler F, Sewald K, Williams DM, Coggeshall KM, Awasthi S, Lupu F, Burian D, Ballard JD, Braun A, Metcalf JP. Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function. Infect Immun. 2012 Dec; 80(12):4374-87. PMID: 23027535; PMCID: PMC3497415.
    10. Sun D, Raisley B, Langer M, Iyer JK, Vedham V, Ballard JL, James JA, Metcalf J, Coggeshall KM. Anti-peptidoglycan antibodies and Fc? receptors are the key mediators of inflammation in Gram-positive sepsis. J Immunol. 2012 Sep 01; 189(5):2423-31. PMID: 22815288; PMCID: PMC3424298.
    11. Iyer JK, Coggeshall KM. Cutting edge: primary innate immune cells respond efficiently to polymeric peptidoglycan, but not to peptidoglycan monomers. J Immunol. 2011 Apr 01; 186(7):3841-5. PMID: 21357534; PMCID: PMC3071148.
    12. Peng Q, Malhotra S, Torchia JA, Kerr WG, Coggeshall KM, Humphrey MB. TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1. Sci Signal. 2010 May 18; 3(122):ra38. PMID: 20484116; PMCID: PMC2900152.
    13. Maeda K, Mehta H, Drevets DA, Coggeshall KM. IL-6 increases B-cell IgG production in a feed-forward proinflammatory mechanism to skew hematopoiesis and elevate myeloid production. Blood. 2010 Jun 10; 115(23):4699-706. PMID: 20351305; PMCID: PMC3790945.
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