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Michael T Ashby

TitleProfessor
InstitutionUniversity of Oklahoma, Norman
DepartmentChemistry/Biochemistry
Address620 Parrington Oval
Norman OK
Phone405/325-2924
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    Collapse Research 
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    R21DE016889     (ASHBY, MICHAEL T)Feb 1, 2007 - Jan 31, 2010
    NIH/NIDCR
    Inorganic Antimicrobials in Exocrine Fluids
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Cupp-Sutton KA, Ashby MT. Biological Chemistry of Hydrogen Selenide. Antioxidants (Basel). 2016 Nov 22; 5(4). PMID: 27879667.
      View in: PubMed
    2. Bonifay V, Barrett TJ, Pattison DI, Davies MJ, Hawkins CL, Ashby MT. Tryptophan oxidation in proteins exposed to thiocyanate-derived oxidants. Arch Biochem Biophys. 2014 Dec 15; 564:1-11. PMID: 25172223.
      View in: PubMed
    3. Kalmár J, Ellis SB, Ashby MT, Halterman RL. Kinetics of formation of the host-guest complex of a viologen with cucurbit[7]uril. Org Lett. 2012 Jul 06; 14(13):3248-51. PMID: 22690827.
      View in: PubMed
    4. Zhai Z, Gomez-Mejiba SE, Gimenez MS, Deterding LJ, Tomer KB, Mason RP, Ashby MT, Ramirez DC. Free radical-operated proteotoxic stress in macrophages primed with lipopolysaccharide. Free Radic Biol Med. 2012 Jul 01; 53(1):172-81. PMID: 22580125; PMCID: PMC4078023.
    5. Kalmár J, Woldegiorgis KL, Biri B, Ashby MT. Mechanism of decomposition of the human defense factor hypothiocyanite near physiological pH. J Am Chem Soc. 2011 Dec 14; 133(49):19911-21. PMID: 22031955.
      View in: PubMed
    6. Zheng L, Chen Z, Itzek A, Ashby M, Kreth J. Catabolite control protein A controls hydrogen peroxide production and cell death in Streptococcus sanguinis. J Bacteriol. 2011 Jan; 193(2):516-26. PMID: 21036992; PMCID: PMC3019840.
    7. Gomez-Mejiba SE, Zhai Z, Gimenez MS, Ashby MT, Chilakapati J, Kitchin K, Mason RP, Ramirez DC. Myeloperoxidase-induced genomic DNA-centered radicals. J Biol Chem. 2010 Jun 25; 285(26):20062-71. PMID: 20406811; PMCID: PMC2888418.
    8. Xulu BA, Ashby MT. Small molecular, macromolecular, and cellular chloramines react with thiocyanate to give the human defense factor hypothiocyanite. Biochemistry. 2010 Mar 09; 49(9):2068-74. PMID: 20085320; PMCID: PMC2831154.
    9. Ueki H, Chapman G, Ashby MT. Reactive sulfur species: kinetics and mechanism of the oxidation of aryl sulfinates with hypochlorous acid. J Phys Chem A. 2010 Feb 04; 114(4):1670-6. PMID: 20039719.
      View in: PubMed
    10. Beal JL, Foster SB, Ashby MT. Hypochlorous acid reacts with the N-terminal methionines of proteins to give dehydromethionine, a potential biomarker for neutrophil-induced oxidative stress. Biochemistry. 2009 Nov 24; 48(46):11142-8. PMID: 19839600; PMCID: PMC2796370.
    11. Lemma K, Ashby MT. Reactive sulfur species: kinetics and mechanism of the reaction of hypothiocyanous acid with cyanide to give dicyanosulfide in aqueous solution. Chem Res Toxicol. 2009 Sep; 22(9):1622-8. PMID: 19705807.
      View in: PubMed
    12. Ashby MT, Kreth J, Soundarajan M, Sivuilu LS. Influence of a model human defensive peroxidase system on oral streptococcal antagonism. Microbiology. 2009 Nov; 155(Pt 11):3691-700. PMID: 19684069; PMCID: PMC2888128.
    13. Wang X, Ashby MT. Reactive sulfur species: kinetics and mechanism of the reaction of thiocarbamate-S-oxide with cysteine. Chem Res Toxicol. 2008 Nov; 21(11):2120-6. PMID: 18942795.
      View in: PubMed
    14. Ashby MT. Inorganic chemistry of defensive peroxidases in the human oral cavity. J Dent Res. 2008 Oct; 87(10):900-14. PMID: 18809743.
      View in: PubMed
    15. Harwood DT, Nimmo SL, Kettle AJ, Winterbourn CC, Ashby MT. Molecular structure and dynamic properties of a sulfonamide derivative of glutathione that is produced under conditions of oxidative stress by hypochlorous acid. Chem Res Toxicol. 2008 May; 21(5):1011-6. PMID: 18447396.
      View in: PubMed
    16. Lemma K, Ashby MT. Reactive sulfur species: kinetics and mechanism of the equilibrium between cysteine sulfenyl thiocyanate and cysteine thiosulfinate ester in acidic aqueous solution. J Org Chem. 2008 Apr 18; 73(8):3017-23. PMID: 18351774.
      View in: PubMed
    17. Nagy P, Wang X, Lemma K, Ashby MT. Reactive sulfur species: hydrolysis of hypothiocyanite to give thiocarbamate-S-oxide. J Am Chem Soc. 2007 Dec 26; 129(51):15756-7. PMID: 18052381.
      View in: PubMed
    18. Nagy P, Lemma K, Ashby MT. Reactive sulfur species: kinetics and mechanisms of the reaction of cysteine thiosulfinate ester with cysteine to give cysteine sulfenic acid. J Org Chem. 2007 Nov 09; 72(23):8838-46. PMID: 17941676.
      View in: PubMed
    19. Nagy P, Ashby MT. Reactive sulfur species: kinetics and mechanisms of the oxidation of cysteine by hypohalous acid to give cysteine sulfenic acid. J Am Chem Soc. 2007 Nov 14; 129(45):14082-91. PMID: 17939659.
      View in: PubMed
    20. Nagy P, Ashby MT. Reactive sulfur species: kinetics and mechanism of the hydrolysis of cysteine thiosulfinate ester. Chem Res Toxicol. 2007 Sep; 20(9):1364-72. PMID: 17764150.
      View in: PubMed
    21. Nagy P, Lemma K, Ashby MT. Kinetics and mechanism of the comproportionation of hypothiocyanous acid and thiocyanate to give thiocyanogen in acidic aqueous solution. Inorg Chem. 2007 Jan 08; 46(1):285-92. PMID: 17198438.
      View in: PubMed
    22. Nagy P, Ashby MT. Kinetics and mechanism of the oxidation of the glutathione dimer by hypochlorous Acid and catalytic reduction of the chloroamine product by glutathione reductase. Chem Res Toxicol. 2007 Jan; 20(1):79-87. PMID: 17226929.
      View in: PubMed
    23. Nagy P, Alguindigue SS, Ashby MT. Lactoperoxidase-catalyzed oxidation of thiocyanate by hydrogen peroxide: a reinvestigation of hypothiocyanite by nuclear magnetic resonance and optical spectroscopy. Biochemistry. 2006 Oct 17; 45(41):12610-6. PMID: 17029415.
      View in: PubMed
    24. Nagy P, Beal JL, Ashby MT. Thiocyanate is an efficient endogenous scavenger of the phagocytic killing agent hypobromous acid. Chem Res Toxicol. 2006 Apr; 19(4):587-93. PMID: 16608171.
      View in: PubMed
    25. Ashby MT, Nagy P. On the kinetics and mechanism of the reaction of cysteine and hydrogen peroxide in aqueous solution. J Pharm Sci. 2006 Jan; 95(1):15-8. PMID: 16299779.
      View in: PubMed
    26. Mallo RC, Ashby MT. AqpZ-mediated water permeability in Escherichia coli measured by stopped-flow spectroscopy. J Bacteriol. 2006 Jan; 188(2):820-2. PMID: 16385074; PMCID: PMC1347286.
    27. Nagy P, Ashby MT. Reactive sulfur species: kinetics and mechanism of the oxidation of cystine by hypochlorous acid to give N,N'-dichlorocystine. Chem Res Toxicol. 2005 Jun; 18(6):919-23. PMID: 15962926.
      View in: PubMed
    28. Ashby MT, Carlson AC, Scott MJ. Redox buffering of hypochlorous acid by thiocyanate in physiologic fluids. J Am Chem Soc. 2004 Dec 15; 126(49):15976-7. PMID: 15584727.
      View in: PubMed
    29. Ashby MT, Aneetha H. Reactive sulfur species: aqueous chemistry of sulfenyl thiocyanates. J Am Chem Soc. 2004 Aug 25; 126(33):10216-7. PMID: 15315413.
      View in: PubMed
    30. Schwane JD, Ashby MT. FTIR investigation of the intermediates formed in the reaction of nitroprusside and thiolates. J Am Chem Soc. 2002 Jun 19; 124(24):6822-3. PMID: 12059192.
      View in: PubMed
    31. McGuire DG, Khan MA, Ashby MT. Discontinuum between a thiolate and a thiol ligand. Inorg Chem. 2002 Apr 22; 41(8):2202-8. PMID: 11952375.
      View in: PubMed
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