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Steven Dwight Chernausek

TitleProf,Clin
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentDept of Pediatrics
Phone405/271-8001
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    R01DK089034     (CHERNAUSEK, STEVEN D)Aug 4, 2010 - May 31, 2015
    NIH/NIDDK
    Prenatal Conditions and the Pathway to Obesity and Diabetes in Children
    Role: Principal Investigator

    R29NS025354     (CHERNAUSEK, STEVEN D)Apr 1, 1987 - Oct 1, 1992
    NIH/NINDS
    SOMATOMEDINS AND BRAIN DEVELOPMENT
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Jiang S, Teague AM, Tryggestad JB, Lyons TJ, Chernausek SD. Fetal circulating human resistin increases in diabetes during pregnancy and impairs placental mitochondrial biogenesis. Mol Med. 2020 Aug 06; 26(1):76. PMID: 32762639.
      View in: PubMed
    2. Shah KB, Chernausek SD, Teague AM, Bard DE, Tryggestad JB. Maternal diabetes alters microRNA expression in fetal exosomes, human umbilical vein endothelial cells and placenta. Pediatr Res. 2020 Jul 14. PMID: 32663836.
      View in: PubMed
    3. Jiang S, Teague AM, Tryggestad JB, Jensen ME, Chernausek SD. Role of metformin in epigenetic regulation of placental mitochondrial biogenesis in maternal diabetes. Sci Rep. 2020 May 20; 10(1):8314. PMID: 32433500.
      View in: PubMed
    4. Tryggestad JB, Chernausek SD. BMI changes through childhood: the impact on puberty, linear growth and hormonal regulation. Pediatr Res. 2020 07; 88(1):11-13. PMID: 32299087.
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    5. Arslanian S, El Ghormli L, Haymond MH, Chan CL, Chernausek SD, Gandica RG, Gubitosi-Klug R, Levitsky LL, Siska M, Willi SM. Beta cell function and insulin sensitivity in obese youth with maturity onset diabetes of youth mutations vs type 2 diabetes in TODAY: Longitudinal observations and glycemic failure. Pediatr Diabetes. 2020 06; 21(4):575-585. PMID: 32064729.
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    6. Tryggestad JB, Teague AM, Sparling DP, Jiang S, Chernausek SD. Macrophage-Derived microRNA-155 Increases in Obesity and Influences Adipocyte Metabolism by Targeting Peroxisome Proliferator-Activated Receptor Gamma. Obesity (Silver Spring). 2019 11; 27(11):1856-1864. PMID: 31531958.
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    7. Alexander J, Teague AM, Chen J, Aston CE, Leung YK, Chernausek S, Simmons RA, Pinney SE. Offspring sex impacts DNA methylation and gene expression in placentae from women with diabetes during pregnancy. PLoS One. 2018; 13(2):e0190698. PMID: 29470513.
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    8. Murray PG, Clayton PE, Chernausek SD. A genetic approach to evaluation of short stature of undetermined cause. Lancet Diabetes Endocrinol. 2018 07; 6(7):564-574. PMID: 29397377.
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    9. Jiang S, Teague AM, Tryggestad JB, Aston CE, Lyons T, Chernausek SD. Effects of maternal diabetes and fetal sex on human placenta mitochondrial biogenesis. Placenta. 2017 Sep; 57:26-32. PMID: 28864016.
      View in: PubMed
    10. Shaw ND, Brand H, Kupchinsky ZA, Bengani H, Plummer L, Jones TI, Erdin S, Williamson KA, Rainger J, Stortchevoi A, Samocha K, Currall BB, Dunican DS, Collins RL, Willer JR, Lek A, Lek M, Nassan M, Pereira S, Kammin T, Lucente D, Silva A, Seabra CM, Chiang C, An Y, Ansari M, Rainger JK, Joss S, Smith JC, Lippincott MF, Singh SS, Patel N, Jing JW, Law JR, Ferraro N, Verloes A, Rauch A, Steindl K, Zweier M, Scheer I, Sato D, Okamoto N, Jacobsen C, Tryggestad J, Chernausek S, Schimmenti LA, Brasseur B, Cesaretti C, García-Ortiz JE, Buitrago TP, Silva OP, Hoffman JD, Mühlbauer W, Ruprecht KW, Loeys BL, Shino M, Kaindl AM, Cho CH, Morton CC, Meehan RR, van Heyningen V, Liao EC, Balasubramanian R, Hall JE, Seminara SB, Macarthur D, Moore SA, Yoshiura KI, Gusella JF, Marsh JA, Graham JM, Lin AE, Katsanis N, Jones PL, Crowley WF, Davis EE, FitzPatrick DR, Talkowski ME. Corrigendum: SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome. Nat Genet. 2017 05 26; 49(6):969. PMID: 28546579.
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    11. Jiang S, Teague AM, Tryggestad JB, Chernausek SD. Role of microRNA-130b in placental PGC-1a/TFAM mitochondrial biogenesis pathway. Biochem Biophys Res Commun. 2017 06 03; 487(3):607-612. PMID: 28433632.
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    12. Shaw ND, Brand H, Kupchinsky ZA, Bengani H, Plummer L, Jones TI, Erdin S, Williamson KA, Rainger J, Stortchevoi A, Samocha K, Currall BB, Dunican DS, Collins RL, Willer JR, Lek A, Lek M, Nassan M, Pereira S, Kammin T, Lucente D, Silva A, Seabra CM, Chiang C, An Y, Ansari M, Rainger JK, Joss S, Smith JC, Lippincott MF, Singh SS, Patel N, Jing JW, Law JR, Ferraro N, Verloes A, Rauch A, Steindl K, Zweier M, Scheer I, Sato D, Okamoto N, Jacobsen C, Tryggestad J, Chernausek S, Schimmenti LA, Brasseur B, Cesaretti C, García-Ortiz JE, Buitrago TP, Silva OP, Hoffman JD, Mühlbauer W, Ruprecht KW, Loeys BL, Shino M, Kaindl AM, Cho CH, Morton CC, Meehan RR, van Heyningen V, Liao EC, Balasubramanian R, Hall JE, Seminara SB, Macarthur D, Moore SA, Yoshiura KI, Gusella JF, Marsh JA, Graham JM, Lin AE, Katsanis N, Jones PL, Crowley WF, Davis EE, FitzPatrick DR, Talkowski ME. SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome. Nat Genet. 2017 Feb; 49(2):238-248. PMID: 28067909.
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    13. Tryggestad JB, Vishwanath A, Jiang S, Mallappa A, Teague AM, Takahashi Y, Thompson DM, Chernausek SD. Influence of gestational diabetes mellitus on human umbilical vein endothelial cell miRNA. Clin Sci (Lond). 2016 11 01; 130(21):1955-67. PMID: 27562513.
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    14. Copeland KC, Chernausek S. Mini-Puberty and Growth. Pediatrics. 2016 07; 138(1). PMID: 27283014.
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    15. Chernausek SD, Arslanian S, Caprio S, Copeland KC, El ghormli L, Kelsey MM, Koontz MB, Orsi CM, Wilfley D. Relationship Between Parental Diabetes and Presentation of Metabolic and Glycemic Function in Youth With Type 2 Diabetes: Baseline Findings From the TODAY Trial. Diabetes Care. 2016 Jan; 39(1):110-7. PMID: 26577415.
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    16. Ziegler EE, Fields DA, Chernausek SD, Steenhout P, Grathwohl D, Jeter JM, Nelson SE, Haschke F. Adequacy of Infant Formula With Protein Content of 1.6 g/100 kcal for Infants Between 3 and 12 Months. J Pediatr Gastroenterol Nutr. 2015 Nov; 61(5):596-603. PMID: 26154030.
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    17. Teague AM, Fields DA, Aston CE, Short KR, Lyons TJ, Chernausek SD. Cord blood adipokines, neonatal anthropometrics and postnatal growth in offspring of Hispanic and Native American women with diabetes mellitus. Reprod Biol Endocrinol. 2015 Jun 26; 13:68. PMID: 26111704.
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    18. Backeljauw PF, Bondy C, Chernausek SD, Cernich JT, Cole DA, Fasciano LP, Foodim J, Hawley S, Hong DS, Knickmeyer RC, Kruszka P, Lin AE, Lippe BM, Lorigan GA, Maslen CL, Mauras N, Page DC, Pemberton VL, Prakash SK, Quigley CA, Ranallo KC, Reiss AL, Sandberg DE, Scurlock C, Silberbach M. Proceedings from the Turner Resource Network symposium: the crossroads of health care research and health care delivery. Am J Med Genet A. 2015 Sep; 167A(9):1962-71. PMID: 25920614.
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    19. Short KR, Teague AM, Fields DA, Lyons T, Chernausek SD. Lower resting energy expenditure and fat oxidation in Native American and Hispanic infants born to mothers with diabetes. J Pediatr. 2015 Apr; 166(4):884-9. PMID: 25648295.
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    20. Chernausek SD. Whole exome sequencing in short stature: finding needles in the haystack. Horm Res Paediatr. 2014; 82(1):1-2. PMID: 25034399.
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    21. Xanthakos SA, Crimmins NA, Chernausek SD. Abnormalities in the growth hormone axis and risk of nonalcoholic steatohepatitis: active player or innocent bystander? J Pediatr. 2014 Jul; 165(1):12-4. PMID: 24793205.
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    22. Backeljauw PF, Kuntze J, Frane J, Calikoglu AS, Chernausek SD. Adult and near-adult height in patients with severe insulin-like growth factor-I deficiency after long-term therapy with recombinant human insulin-like growth factor-I. Horm Res Paediatr. 2013; 80(1):47-56. PMID: 23887143.
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    23. Tryggestad JB, Li S, Chernausek SD. Hypogonadotropic hypogonadism presenting with arhinia: a case report. J Med Case Rep. 2013 Feb 22; 7:52. PMID: 23432817.
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    24. Creighton S, Chernausek SD, Romao R, Ransley P, Salle JP. Timing and nature of reconstructive surgery for disorders of sex development - introduction. J Pediatr Urol. 2012 Dec; 8(6):602-10. PMID: 23146296.
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    25. Shankar RK, Rutter MJ, Chernausek SD, Samuels PJ, Mo JQ, Rutter MM. Medullary thyroid cancer in a 9-week-old infant with familial MEN 2B: Implications for timing of prophylactic thyroidectomy. Int J Pediatr Endocrinol. 2012 Sep 19; 2012(1):25. PMID: 22992277.
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    26. Kansra AR, Dolan LM, Martin LJ, Deka R, Chernausek SD. IGF receptor gene variants in normal adolescents: effect on stature. Eur J Endocrinol. 2012 Dec; 167(6):777-81. PMID: 22972910.
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    27. Wolfe-Christensen C, Fedele DA, Kirk K, Phillips TM, Mazur T, Mullins LL, Chernausek SD, Lakshmanan Y, Wisniewski AB. Degree of external genital malformation at birth in children with a disorder of sex development and subsequent caregiver distress. J Urol. 2012 Oct; 188(4 Suppl):1596-600. PMID: 22910249.
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    28. Backeljauw PF, Chernausek SD. The insulin-like growth factors and growth disorders of childhood. Endocrinol Metab Clin North Am. 2012 Jun; 41(2):265-82, v. PMID: 22682630.
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    29. Chernausek SD. Update: consequences of abnormal fetal growth. J Clin Endocrinol Metab. 2012 Mar; 97(3):689-95. PMID: 22238390.
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    30. Palmer BW, Wisniewski AB, Schaeffer TL, Mallappa A, Tryggestad JB, Krishnan S, Chalmers LJ, Copeland K, Chernausek SD, Reiner WG, Kropp BP. A model of delivering multi-disciplinary care to people with 46 XY DSD. J Pediatr Urol. 2012 Feb; 8(1):7-16. PMID: 22078657.
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    31. Chernausek SD. Criteria for treating children with idiopathic short stature: laboratory (biochemical). Horm Res Paediatr. 2011; 76 Suppl 3:18-20. PMID: 21912152.
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    32. Kirk KD, Fedele DA, Wolfe-Christensen C, Phillips TM, Mazur T, Mullins LL, Chernausek SD, Wisniewski AB. Parenting characteristics of female caregivers of children affected by chronic endocrine conditions: a comparison between disorders of sex development and type 1 diabetes mellitus. J Pediatr Nurs. 2011 Dec; 26(6):e29-36. PMID: 21911316.
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    33. Sisson SB, Broyles ST, Newton RL, Baker BL, Chernausek SD. TVs in the bedrooms of children: does it impact health and behavior? Prev Med. 2011 Feb; 52(2):104-8. PMID: 21130109.
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    34. Fedele DA, Kirk K, Wolfe-Christensen C, Phillips TM, Mazur T, Mullins LL, Chernausek SD, Wisniewski AB. Primary caregivers of children affected by disorders of sex development: mental health and caregiver characteristics in the context of genital ambiguity and genitoplasty. Int J Pediatr Endocrinol. 2010; 2010:690674. PMID: 20628508.
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    35. Chernausek SD. Growth and development: how safe is growth hormone therapy for children? Nat Rev Endocrinol. 2010 May; 6(5):251-3. PMID: 20414318.
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    36. Schaeffer TL, Tryggestad JB, Mallappa A, Hanna AE, Krishnan S, Chernausek SD, Chalmers LJ, Reiner WG, Kropp BP, Wisniewski AB. An Evidence-Based Model of Multidisciplinary Care for Patients and Families Affected by Classical Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency. Int J Pediatr Endocrinol. 2010; 2010:692439. PMID: 20339513.
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    37. Chernausek SD. Growth hormone-resistant syndromes: long-term follow-up. Endocr Dev. 2009; 14:135-42. PMID: 19293580.
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    38. Wisniewski AB, Chernausek SD. Gender in childhood obesity: family environment, hormones, and genes. Gend Med. 2009; 6 Suppl 1:76-85. PMID: 19318220.
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    39. Chernausek S. Evaluation of an insulin-like growth factor I-based growth hormone dosing regimen for children with short stature. Nat Clin Pract Endocrinol Metab. 2007 Oct; 3(10):682-3. PMID: 17667897.
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    40. Chernausek SD, Backeljauw PF, Frane J, Kuntze J, Underwood LE. Long-term treatment with recombinant insulin-like growth factor (IGF)-I in children with severe IGF-I deficiency due to growth hormone insensitivity. J Clin Endocrinol Metab. 2007 Mar; 92(3):902-10. PMID: 17192294.
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    41. Pinhas-Hamiel O, Chernausek SD, Zeitler P. Acute necrotizing pancreatitis in an adolescent with type 2 diabetes. Curr Opin Pediatr. 2006 Apr; 18(2):206-8. PMID: 16601505.
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    42. Backeljauw PF, Chernausek SD. Treatment of insulin-like growth factor deficiency with IGF-I: studies in humans. Horm Res. 2006; 65 Suppl 1:21-7. PMID: 16508330.
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    43. Rutter MM, Markoff E, Clayton L, Akeno N, Zhao G, Clemens TL, Chernausek SD. Osteoblast-specific expression of insulin-like growth factor-1 in bone of transgenic mice induces insulin-like growth factor binding protein-5. Bone. 2005 Feb; 36(2):224-31. PMID: 15780948.
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    44. Chernausek SD. Treatment of short children born small for gestational age: US perspective, 2005. Horm Res. 2005; 64 Suppl 2:63-6. PMID: 16286774.
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    45. Clemens TL, Chernausek SD. Genetic strategies for elucidating insulin-like growth factor action in bone. Growth Horm IGF Res. 2004 Jun; 14(3):195-9. PMID: 15125880.
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    46. Chernausek SD. Growth hormone treatment of short children born small for gestational age: a US perspective. Horm Res. 2004; 62 Suppl 3:124-7. PMID: 15539813.
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    47. Abuzzahab MJ, Schneider A, Goddard A, Grigorescu F, Lautier C, Keller E, Kiess W, Klammt J, Kratzsch J, Osgood D, Pfäffle R, Raile K, Seidel B, Smith RJ, Chernausek SD. IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation. N Engl J Med. 2003 Dec 04; 349(23):2211-22. PMID: 14657428.
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    48. Lee PA, Chernausek SD, Hokken-Koelega AC, Czernichow P. International Small for Gestational Age Advisory Board consensus development conference statement: management of short children born small for gestational age, April 24-October 1, 2001. Pediatrics. 2003 Jun; 111(6 Pt 1):1253-61. PMID: 12777538.
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    49. Zhang M, Faugere MC, Malluche H, Rosen CJ, Chernausek SD, Clemens TL. Paracrine overexpression of IGFBP-4 in osteoblasts of transgenic mice decreases bone turnover and causes global growth retardation. J Bone Miner Res. 2003 May; 18(5):836-43. PMID: 12733722.
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    50. Chernausek SD. Development of a consensus statement on management of short children born small for gestational age. J Pediatr Endocrinol Metab. 2002 Dec; 15 Suppl 5:1275. PMID: 12510979.
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    51. Zhang M, Smith EP, Kuroda H, Banach W, Chernausek SD, Fagin JA. Targeted expression of a protease-resistant IGFBP-4 mutant in smooth muscle of transgenic mice results in IGFBP-4 stabilization and smooth muscle hypotrophy. J Biol Chem. 2002 Jun 14; 277(24):21285-90. PMID: 11923290.
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