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Thomas W Seale

TitleProfessor
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentDept of Pediatrics
Address940 NE 13th St
Oklahoma City OK 73104-5008
Phone405/271-6451
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    R03MH049791     (SEALE, THOMAS W)Sep 30, 1992 - Aug 31, 1994
    NIH/NIMH
    NOVEL MURINE MODEL RESPONSIVE TO ANXIOLYTICS
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Guan X, Seale TW, Gan RZ. Factors affecting sound energy absorbance in acute otitis media model of chinchilla. Hear Res. 2017 Jul; 350:22-31. PMID: 28426992.
      View in: PubMed
    2. Jiang S, Seale TW, Gan RZ. Morphological changes in the round window membrane associated with Haemophilus influenzae-induced acute otitis media in the chinchilla. Int J Pediatr Otorhinolaryngol. 2016 Sep; 88:74-81. PMID: 27497390; PMCID: PMC4978205 [Available on 09/01/17].
    3. Mussa HJ, VanWagoner TM, Morton DJ, Seale TW, Whitby PW, Stull TL. Draft Genome Sequences of Eight Nontypeable Haemophilus influenzae Strains Previously Characterized Using an Electrophoretic Typing Scheme. Genome Announc. 2015 Nov 25; 3(6). PMID: 26607889; PMCID: PMC4661308.
    4. VanWagoner TM, Morton DJ, Seale TW, Mussa HJ, Cole BK, Whitby PW, Stull TL. Draft Genome Sequences of Six Nontypeable Haemophilus influenzae Strains That Establish Bacteremia in the Infant Rat Model of Invasive Disease. Genome Announc. 2015 Sep 24; 3(5). PMID: 26404588; PMCID: PMC4582564.
    5. Whitby PW, Seale TW, Morton DJ, Stull TL. Antisera Against Certain Conserved Surface-Exposed Peptides of Nontypeable Haemophilus influenzae Are Protective. PLoS One. 2015; 10(9):e0136867. PMID: 26390432; PMCID: PMC4577129.
    6. Guan X, Jiang S, Seale TW, Hitt BM, Gan RZ. Morphological changes in the tympanic membrane associated with Haemophilus influenzae-induced acute otitis media in the chinchilla. Int J Pediatr Otorhinolaryngol. 2015 Sep; 79(9):1462-71. PMID: 26183006.
      View in: PubMed
    7. Whitby PW, VanWagoner TM, Seale TW, Morton DJ, Stull TL. Comparison of transcription of the Haemophilus influenzae iron/heme modulon genes in vitro and in vivo in the chinchilla middle ear. BMC Genomics. 2013 Dec 27; 14:925. PMID: 24373462; PMCID: PMC3879429.
    8. Hempel RJ, Morton DJ, Seale TW, Whitby PW, Stull TL. The role of the RNA chaperone Hfq in Haemophilus influenzae pathogenesis. BMC Microbiol. 2013 Jun 16; 13:134. PMID: 23767779; PMCID: PMC3691723.
    9. Whitby PW, Morton DJ, Vanwagoner TM, Seale TW, Cole BK, Mussa HJ, McGhee PA, Bauer CY, Springer JM, Stull TL. Haemophilus influenzae OxyR: characterization of its regulation, regulon and role in fitness. PLoS One. 2012; 7(11):e50588. PMID: 23226321; PMCID: PMC3511568.
    10. Whitby PW, VanWagoner TM, Morton DJ, Seale TW, Springer JM, Hempel RJ, Stull TL. Signature-tagging of a bacterial isolate demonstrates phenotypic variability of the progeny in vivo in the absence of defined mutations. J Microbiol Methods. 2012 Dec; 91(3):336-40. PMID: 23085534; PMCID: PMC3506178.
    11. Morton DJ, Hempel RJ, Seale TW, Whitby PW, Stull TL. A functional tonB gene is required for both virulence and competitive fitness in a chinchilla model of Haemophilus influenzae otitis media. BMC Res Notes. 2012 Jun 25; 5:327. PMID: 22731867; PMCID: PMC3425130.
    12. Morton DJ, Hempel RJ, Whitby PW, Seale TW, Stull TL. An invasive Haemophilus haemolyticus isolate. J Clin Microbiol. 2012 Apr; 50(4):1502-3. PMID: 22301029; PMCID: PMC3318549.
    13. Morton DJ, Turman EJ, Hensley PD, VanWagoner TM, Seale TW, Whitby PW, Stull TL. Identification of a siderophore utilization locus in nontypeable Haemophilus influenzae. BMC Microbiol. 2010 Apr 15; 10:113. PMID: 20398325; PMCID: PMC2859871.
    14. Whitby PW, Seale TW, Morton DJ, VanWagoner TM, Stull TL. Characterization of the Haemophilus influenzae tehB gene and its role in virulence. Microbiology. 2010 Apr; 156(Pt 4):1188-200. PMID: 20075041; PMCID: PMC2889444.
    15. Morton DJ, Seale TW, Vanwagoner TM, Whitby PW, Stull TL. The dppBCDF gene cluster of Haemophilus influenzae: Role in heme utilization. BMC Res Notes. 2009 Aug 24; 2:166. PMID: 19703293; PMCID: PMC2738685.
    16. Morton DJ, Seale TW, Bakaletz LO, Jurcisek JA, Smith A, VanWagoner TM, Whitby PW, Stull TL. The heme-binding protein (HbpA) of Haemophilus influenzae as a virulence determinant. Int J Med Microbiol. 2009 Nov; 299(7):479-88. PMID: 19451029; PMCID: PMC2749905.
    17. Whitby PW, Seale TW, VanWagoner TM, Morton DJ, Stull TL. The iron/heme regulated genes of Haemophilus influenzae: comparative transcriptional profiling as a tool to define the species core modulon. BMC Genomics. 2009 Jan 07; 10:6. PMID: 19128474; PMCID: PMC2627913.
    18. Morton DJ, VanWagoner TM, Seale TW, Whitby PW, Stull TL. Catalase as a source of both X- and V-factor for Haemophilus influenzae. FEMS Microbiol Lett. 2008 Feb; 279(2):157-61. PMID: 18093136.
      View in: PubMed
    19. Morton DJ, Smith A, VanWagoner TM, Seale TW, Whitby PW, Stull TL. Lipoprotein e (P4) of Haemophilus influenzae: role in heme utilization and pathogenesis. Microbes Infect. 2007 Jul; 9(8):932-9. PMID: 17548224; PMCID: PMC1975679.
    20. Morton DJ, Seale TW, Madore LL, VanWagoner TM, Whitby PW, Stull TL. The haem-haemopexin utilization gene cluster (hxuCBA) as a virulence factor of Haemophilus influenzae. Microbiology. 2007 Jan; 153(Pt 1):215-24. PMID: 17185550.
      View in: PubMed
    21. Seale TW, Morton DJ, Whitby PW, Wolf R, Kosanke SD, VanWagoner TM, Stull TL. Complex role of hemoglobin and hemoglobin-haptoglobin binding proteins in Haemophilus influenzae virulence in the infant rat model of invasive infection. Infect Immun. 2006 Nov; 74(11):6213-25. PMID: 16966415; PMCID: PMC1695506.
    22. Whitby PW, Vanwagoner TM, Seale TW, Morton DJ, Stull TL. Transcriptional profile of Haemophilus influenzae: effects of iron and heme. J Bacteriol. 2006 Aug; 188(15):5640-5. PMID: 16855256; PMCID: PMC1540045.
    23. Whitby PW, Vanwagoner TM, Springer JM, Morton DJ, Seale TW, Stull TL. Burkholderia cenocepacia utilizes ferritin as an iron source. J Med Microbiol. 2006 Jun; 55(Pt 6):661-8. PMID: 16687582.
      View in: PubMed
    24. Morton DJ, Van Wagoner TM, Seale TW, Whitby PW, Stull TL. Utilization of myoglobin as a heme source by Haemophilus influenzae requires binding of myoglobin to haptoglobin. FEMS Microbiol Lett. 2006 May; 258(2):235-40. PMID: 16640579.
      View in: PubMed
    25. Morton DJ, VanWagoner TM, Seale TW, Whitby PW, Stull TL. Differential utilization by Haemophilus influenzae of haemoglobin complexed to the three human haptoglobin phenotypes. FEMS Immunol Med Microbiol. 2006 Apr; 46(3):426-32. PMID: 16553817.
      View in: PubMed
    26. Whitby PW, VanWagoner TM, Taylor AA, Seale TW, Morton DJ, LiPuma JJ, Stull TL. Identification of an RTX determinant of Burkholderia cenocepacia J2315 by subtractive hybridization. J Med Microbiol. 2006 Jan; 55(Pt 1):11-21. PMID: 16388025.
      View in: PubMed
    27. Morton DJ, Madore LL, Smith A, Vanwagoner TM, Seale TW, Whitby PW, Stull TL. The heme-binding lipoprotein (HbpA) of Haemophilus influenzae: role in heme utilization. FEMS Microbiol Lett. 2005 Dec 15; 253(2):193-9. PMID: 16289530.
      View in: PubMed
    28. Morton DJ, Smith A, Ren Z, Madore LL, VanWagoner TM, Seale TW, Whitby PW, Stull TL. Identification of a haem-utilization protein (Hup) in Haemophilus influenzae. Microbiology. 2004 Dec; 150(Pt 12):3923-33. PMID: 15583146.
      View in: PubMed
    29. VanWagoner TM, Whitby PW, Morton DJ, Seale TW, Stull TL. Characterization of three new competence-regulated operons in Haemophilus influenzae. J Bacteriol. 2004 Oct; 186(19):6409-21. PMID: 15375121; PMCID: PMC516621.
    30. Morton DJ, Bakaletz LO, Jurcisek JA, VanWagoner TM, Seale TW, Whitby PW, Stull TL. Reduced severity of middle ear infection caused by nontypeable Haemophilus influenzae lacking the hemoglobin/hemoglobin-haptoglobin binding proteins (Hgp) in a chinchilla model of otitis media. Microb Pathog. 2004 Jan; 36(1):25-33. PMID: 14643637.
      View in: PubMed
    31. Garrett KM, Basmadjian G, Khan IA, Schaneberg BT, Seale TW. Extracts of kava (Piper methysticum) induce acute anxiolytic-like behavioral changes in mice. Psychopharmacology (Berl). 2003 Oct; 170(1):33-41. PMID: 12845414.
      View in: PubMed
    32. Pfefferbaum B, Seale TW, Brandt EN, Pfefferbaum RL, Doughty DE, Rainwater SM. Media exposure in children one hundred miles from a terrorist bombing. Ann Clin Psychiatry. 2003 Mar; 15(1):1-8. PMID: 12839427.
      View in: PubMed
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