Loading...
Header Logo
Keywords
Last Name
Institution

Beverley Greenwood-VanMeerveld

TitleProf
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentPhysiology
Address975 NE 10th St
Oklahoma City OK 73104-5419
Phone405/456-3547
vCardDownload vCard

    Collapse Biography 
    Collapse education and training
    University of Sheffield, Sheffield, U.K. BSc. (Special Honors)1980Physiology
    University of Sheffield, Sheffield, U.K.Ph.D. 1983GI Neurophysiology
    University of Calgary, Calgary, CanadaAlberta Heritage Postdoctoral Research Fellow 1986Gastrointestinal (GI) Research
    Collapse awards and honors
    2017 - 2021President’s Associates Presidential Professor, OUHSC
    2016 - 2018PRESIDENT- Elect , American Neurogastroenterology and Motility Society
    2018 - 2020PRESIDENT, American Neurogastroenterology and Motility Society
    2016 - 2023SENIOR Research Career Scientist Award, Department of Veterans Affairs
    2015 - 2017Chair (elected) , Editorial Board of Neurogastroenterology and Motility
    2016 - 2018Chair: Biomedical Laboratory and Clinical Science R&D Scientific VA Merit Review Board, Department of Veterans Affairs
    2012 - 2016Member (invited) representing Basic Neurogastroenterology, Rome Foundation
    2012 - 2012Member (Invited) representing state of Oklahoma, Dana Alliance for Brain Initiatives
    2012 - 2012Regents Award for Superior Research and Creativity, OUHSC
    2011 - 2017Fellow: American Gastroenterological Association, AGA
    2008Full Professor with Tenure, University of Oklahoma Health Sciences Center
    2007Women of the Year Award Nominee, Oklahoma City, OK
    2007Travel Award, International Neurogastroenterology and Motility meeting, Jeju Island, Korea
    2007Full Professor, University of Oklahoma Health Sciences Center
    2006Travel Award, Brain-Gut Meeting Oxford, England
    2006 - 2011Research Career Scientist Award, Dept. of Veterans Affairs
    2005Travel Award, International Motility meeting, Toulouse, France
    2004Janssen Award for Basic Research in Gastroenterology, Janssen Pharma
    2003Travel Award, AGA, Orlando

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    1I01BX002188-01     (Beverley Greenwood-Van Meerveld)Apr 4, 2005 - Sep 30, 2022
    Department of Veterans Affairs. Merit Review Grant
    Central Mechanisms Modulating Visceral Hypersensitivity
    Role Description: Pending renewal submitted Sept. 2017 This project investigates the affect of amygdala activation on GI function
    Role: PI

    2I01BX001195-05     (Beverley Greenwood-Van Meerveld)Oct 1, 2007 - Sep 30, 2019
    Department of Veterans Affairs
    Understanding Pain of Gastrointestinal Origin in Women that Serve in OEF/OIF
    Role Description: This project investigates the mechanisms underlying the link between stress and behaviors that impact the health and overall quality of life of female Veterans
    Role: PI

    No Number     (Anthony Johnson, Ph.D)Oct 1, 2015 - Apr 30, 2018
    Veterans Research Foundation
    Understanding Stress-Induced Pain In Veterans: Investigation of Novel Brain Circuitry
    Role Description: This is a pilot grant for collecting preliminary data to support a future VA CDA-2 application for Dr. Johnson
    Role: Mentor

    No Number     (Ken Miller)Aug 1, 2016 - Jul 31, 2019
    OCAST
    Neuroimmune and NGF Regulation of Primary Sensory Neuron Function During Irritable Bowel Syndrome
    Role Description: This project will examine the spinal mechanisms of visceral sensitization
    Role: Co-Investigator

    No Number     (Beverley Greenwood-Van Meerveld)Oct 1, 2016 - Sep 30, 2023
    Department of Veterans Affairs
    Senior Research Career Scientist Award
    Role Description: This award provides salary support [partial VA component] to Dr. BGVM
    Role: PI

    No Number     (Beverley Greenwood-Van Meerveld)Oct 19, 2016 - Apr 18, 2018
    Glaxosmithkline
    RET kinase inhibition: a potential novel approach for patients with Chronic Abdominal Pain
    Role Description: This project investigates mechanisms of RET kinase inhibition in experimental models of IBS.
    Role: PI

    No Number     (Beverley Greenwood-Van Meerveld)Mar 15, 2017 - Jan 15, 2020
    TEVA
    Preclinical Investigation of TEV-48125 for the Treatment of Visceral Pain
    Role Description: This project investigates mechanisms of new approach to treat pain
    Role: PI

    No Number     (Beverley Greenwood-Van Meerveld)Oct 5, 2017 - Sep 5, 2018
    Ironwood
    A Study to Investigate Whether Guanyate Cylase Agonism Reverses Amydgala-Mediated Mechanisms Regulating Visceral Hypersensitivity in Adulthood Following Chronic Psychological Stress or Early Life Stress
    Role: PI

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Greenwood-Van Meerveld B,Johnson AC. . Frontiers in Systems Neuroscience. Stress-Induced Chronic Visceral Pain of Gastrointestinal Origin. 2017; 86(11).
    2. Yang Q, Xia D, Towner RA, Smith N, Saunders D, Fung KM, Aston CE, Greenwood-Van Meerveld B, Hurst RE, Madihally SV, Kropp BP, Lin HK. Reduced urothelial regeneration in rat bladders augmented with permeable porcine small intestinal submucosa assessed by magnetic resonance imaging. J Biomed Mater Res B Appl Biomater. 2017 Sep 13. PMID: 28901710.
      View in: PubMed
    3. Hattay P, Prusator DK, Tran L, Greenwood-Van Meerveld B. Psychological stress-induced colonic barrier dysfunction: Role of immune-mediated mechanisms. Neurogastroenterol Motil. 2017 Jul; 29(7). PMID: 28300333.
      View in: PubMed
    4. Prusator DK, Greenwood-Van Meerveld B. Amygdala-mediated mechanisms regulate visceral hypersensitivity in adult females following early life stress: importance of the glucocorticoid receptor and corticotropin-releasing factor. Pain. 2017 Feb; 158(2):296-305. PMID: 27849648.
      View in: PubMed
    5. Greenwood-Van Meerveld B, Johnson AC, Grundy D. Gastrointestinal Physiology and Function. Handb Exp Pharmacol. 2017; 239:1-16. PMID: 28176047.
      View in: PubMed
    6. Johnson AC, Greenwood-Van Meerveld B. Critical Evaluation of Animal Models of Gastrointestinal Disorders. Handb Exp Pharmacol. 2017; 239:289-317. PMID: 28176046.
      View in: PubMed
    7. Prusator DK, Greenwood-Van Meerveld B. Sex differences in stress-induced visceral hypersensitivity following early life adversity: a two hit model. Neurogastroenterol Motil. 2016 Dec; 28(12):1876-1889. PMID: 27385091.
      View in: PubMed
    8. Prusator DK, Andrews A, Greenwood-Van Meerveld B. Neurobiology of early life stress and visceral pain: translational relevance from animal models to patient care. Neurogastroenterol Motil. 2016 Sep; 28(9):1290-305. PMID: 27251368.
      View in: PubMed
    9. Hurst RE, Van Gordon S, Tyler K, Kropp B, Towner R, Lin H, Marentette JO, McHowat J, Mohammedi E, Greenwood-Van Meerveld B. In the absence of overt urothelial damage, chondroitinase ABC digestion of the GAG layer increases bladder permeability in ovariectomized female rats. Am J Physiol Renal Physiol. 2016 May 01; 310(10):F1074-80. PMID: 26911855; PMCID: PMC5002059 [Available on 05/15/17].
    10. Ligon CO, Moloney RD, Greenwood-Van Meerveld B. Targeting Epigenetic Mechanisms for Chronic Pain: A Valid Approach for the Development of Novel Therapeutics. J Pharmacol Exp Ther. 2016 Apr; 357(1):84-93. PMID: 26787772.
      View in: PubMed
    11. Johnson AC, Greenwood-Van Meerveld B. The Pharmacology of Visceral Pain. Adv Pharmacol. 2016; 75:273-301. PMID: 26920016.
      View in: PubMed
    12. Latorre R, Sternini C, De Giorgio R, Greenwood-Van Meerveld B. Enteroendocrine cells: a review of their role in brain-gut communication. Neurogastroenterol Motil. 2016 May; 28(5):620-30. PMID: 26691223; PMCID: PMC4842178 [Available on 05/01/17].
    13. Moloney RD, Johnson AC, O'Mahony SM, Dinan TG, Greenwood-Van Meerveld B, Cryan JF. Stress and the Microbiota-Gut-Brain Axis in Visceral Pain: Relevance to Irritable Bowel Syndrome. CNS Neurosci Ther. 2016 Feb; 22(2):102-17. PMID: 26662472.
      View in: PubMed
    14. Towner RA, Smith N, Saunders D, Van Gordon SB, Tyler KR, Wisniewski AB, Greenwood-Van Meerveld B, Hurst RE. Assessment of colon and bladder crosstalk in an experimental colitis model using contrast-enhanced magnetic resonance imaging. Neurogastroenterol Motil. 2015 Nov; 27(11):1571-9. PMID: 26303228; PMCID: PMC4624485 [Available on 11/01/16].
    15. Towner RA, Wisniewski AB, Wu DH, Van Gordon SB, Smith N, North JC, McElhaney R, Aston CE, Shobeiri SA, Kropp BP, Greenwood-Van Meerveld B, Hurst RE. A Feasibility Study to Determine Whether Clinical Contrast Enhanced Magnetic Resonance Imaging can Detect Increased Bladder Permeability in Patients with Interstitial Cystitis. J Urol. 2016 Mar; 195(3):631-8. PMID: 26307161; PMCID: PMC4760854 [Available on 03/01/17].
    16. Greenwood-Van Meerveld B, Mohammadi E, Tyler K, Van Gordon S, Parker A, Towner R, Hurst R. Mechanisms of Visceral Organ Crosstalk: Importance of Alterations in Permeability in Rodent Models. J Urol. 2015 Sep; 194(3):804-11. PMID: 25776913; PMCID: PMC4699674.
    17. Greenwood-Van Meerveld B, Prusator DK, Johnson AC. Animal models of gastrointestinal and liver diseases. Animal models of visceral pain: pathophysiology, translational relevance, and challenges. Am J Physiol Gastrointest Liver Physiol. 2015 Jun 01; 308(11):G885-903. PMID: 25767262.
      View in: PubMed
    18. Johnson AC, Greenwood-Van Meerveld B. Knockdown of steroid receptors in the central nucleus of the amygdala induces heightened pain behaviors in the rat. Neuropharmacology. 2015 Jun; 93:116-23. PMID: 25656477; PMCID: PMC4929985.
    19. Towner RA, Smith N, Saunders D, Van Gordon SB, Wisniewski AB, Tyler KR, Greenwood-Van Meerveld B, Hurst RE. Contrast enhanced magnetic resonance imaging as a diagnostic tool to assess bladder permeability and associated colon cross talk: preclinical studies in a rat model. J Urol. 2015 Apr; 193(4):1394-400. PMID: 25463988; PMCID: PMC4706081.
    20. Prusator DK, Greenwood-Van Meerveld B. Gender specific effects of neonatal limited nesting on viscerosomatic sensitivity and anxiety-like behavior in adult rats. Neurogastroenterol Motil. 2015 Jan; 27(1):72-81. PMID: 25394875.
      View in: PubMed
    21. Tran L, Schulkin J, Ligon CO, Greenwood-Van Meerveld B. Epigenetic modulation of chronic anxiety and pain by histone deacetylation. Mol Psychiatry. 2015 Oct; 20(10):1219-31. PMID: 25288139.
      View in: PubMed
    22. Mondalek FG, Fung KM, Yang Q, Wu W, Lu W, Palmer BW, Frimberger DC, Greenwood-Van Meerveld B, Hurst RE, Kropp BP, Lin HK. Temporal expression of hyaluronic acid and hyaluronic acid receptors in a porcine small intestinal submucosa-augmented rat bladder regeneration model. World J Urol. 2015 Aug; 33(8):1119-28. PMID: 25253654; PMCID: PMC4699683.
    23. Johnson AC, Greenwood-Van Meerveld B. Stress-induced pain: a target for the development of novel therapeutics. J Pharmacol Exp Ther. 2014 Nov; 351(2):327-35. PMID: 25194019; PMCID: PMC4201269.
    24. Tran L, Schulkin J, Greenwood-Van Meerveld B. Importance of CRF receptor-mediated mechanisms of the bed nucleus of the stria terminalis in the processing of anxiety and pain. Neuropsychopharmacology. 2014 Oct; 39(11):2633-45. PMID: 24853772; PMCID: PMC4207343.
    25. Tran L, Greenwood-Van Meerveld B. In a non-human primate model, aging disrupts the neural control of intestinal smooth muscle contractility in a region-specific manner. Neurogastroenterol Motil. 2014 Mar; 26(3):410-8. PMID: 24548258; PMCID: PMC4077178.
    26. Tran L, Greenwood-Van Meerveld B. Age-associated remodeling of the intestinal epithelial barrier. J Gerontol A Biol Sci Med Sci. 2013 Sep; 68(9):1045-56. PMID: 23873964; PMCID: PMC3738030.
    27. Chaloner A, Greenwood-Van Meerveld B. Early life adversity as a risk factor for visceral pain in later life: importance of sex differences. Front Neurosci. 2013; 7:13. PMID: 23407595; PMCID: PMC3570767.
    28. Chaloner A, Greenwood-Van Meerveld B. Sexually dimorphic effects of unpredictable early life adversity on visceral pain behavior in a rodent model. J Pain. 2013 Mar; 14(3):270-80. PMID: 23348370.
      View in: PubMed
    29. Malykhina AP, Qin C, Lei Q, Pan XQ, Greenwood-Van Meerveld B, Foreman RD. Differential effects of intravesical resiniferatoxin on excitability of bladder spinal neurons upon colon-bladder cross-sensitization. Brain Res. 2013 Jan 23; 1491:213-24. PMID: 23146715; PMCID: PMC3607291.
    30. Greenwood-Van Meerveld B, Kriegsman M, Nelson R. Ghrelin as a target for gastrointestinal motility disorders. Peptides. 2011 Nov; 32(11):2352-6. PMID: 21453735.
      View in: PubMed
    31. Greenwood-Van Meerveld B. Emerging drugs for postoperative ileus. Expert Opin Emerg Drugs. 2007 Nov; 12(4):619-26. PMID: 17979603.
      View in: PubMed
    32. Greenwood-van Meerveld B. Importance of 5-hydroxytryptamine receptors on intestinal afferents in the regulation of visceral sensitivity. Neurogastroenterol Motil. 2007 Aug; 19 Suppl 2:13-8. PMID: 17620083.
      View in: PubMed
    33. Greenwood-Van Meerveld B, Campbell-Dittmeyer K, Johnson AC, Hicks GA. 5-HT2B receptors do not modulate sensitivity to colonic distension in rats with acute colorectal hypersensitivity. Neurogastroenterol Motil. 2006 May; 18(5):343-5. PMID: 16629860.
      View in: PubMed
    34. Greenwood-Van Meerveld B, Johnson AC, Schulkin J, Myers DA. Long-term expression of corticotropin-releasing factor (CRF) in the paraventricular nucleus of the hypothalamus in response to an acute colonic inflammation. Brain Res. 2006 Feb 03; 1071(1):91-6. PMID: 16423333.
      View in: PubMed
    35. Greenwood-Van Meerveld B, Venkova K, Hicks G, Dennis E, Crowell MD. Activation of peripheral 5-HT receptors attenuates colonic sensitivity to intraluminal distension. Neurogastroenterol Motil. 2006 Jan; 18(1):76-86. PMID: 16371086.
      View in: PubMed
    36. Greenwood-Van Meerveld B, Johnson AC, Cochrane S, Schulkin J, Myers DA. Corticotropin-releasing factor 1 receptor-mediated mechanisms inhibit colonic hypersensitivity in rats. Neurogastroenterol Motil. 2005 Jun; 17(3):415-22. PMID: 15916629.
      View in: PubMed
    37. Greenwood-Van Meerveld B, Gardner CJ, Little PJ, Hicks GA, Dehaven-Hudkins DL. Preclinical studies of opioids and opioid antagonists on gastrointestinal function. Neurogastroenterol Motil. 2004 Oct; 16 Suppl 2:46-53. PMID: 15357851.
      View in: PubMed
    38. Greenwood-Van Meerveld B, Gibson MS, Johnson AC, Venkova K, Sutkowski-Markmann D. NK1 receptor-mediated mechanisms regulate colonic hypersensitivity in the guinea pig. Pharmacol Biochem Behav. 2003 Mar; 74(4):1005-13. PMID: 12667916.
      View in: PubMed
    39. Greenwood-Van Meerveld B, Johnson AC, Foreman RD, Linderoth B. Attenuation by spinal cord stimulation of a nociceptive reflex generated by colorectal distention in a rat model. Auton Neurosci. 2003 Feb 28; 104(1):17-24. PMID: 12559199.
      View in: PubMed
    40. Greenwood-Van Meerveld B, Venkova K, Connolly K. Efficacy of repifermin (keratinocyte growth factor-2) against abnormalities in gastrointestinal mucosal transport in a murine model of colitis. J Pharm Pharmacol. 2003 Jan; 55(1):67-75. PMID: 12625869.
      View in: PubMed
    41. Greenwood-Van Meerveld B, Venkova K, Keith JC. Recombinant human interleukin-11 restores smooth muscle function in the jejunum and colon of human leukocyte antigen-B27 rats with intestinal inflammation. J Pharmacol Exp Ther. 2001 Oct; 299(1):58-66. PMID: 11561063.
      View in: PubMed
    42. Greenwood-Van Meerveld B, Gibson M, Gunter W, Shepard J, Foreman R, Myers D. Stereotaxic delivery of corticosterone to the amygdala modulates colonic sensitivity in rats. Brain Res. 2001 Mar 02; 893(1-2):135-42. PMID: 11223001.
      View in: PubMed
    43. Greenwood-Van Meerveld B, Tyler K, Keith JC. Recombinant human interleukin-11 modulates ion transport and mucosal inflammation in the small intestine and colon. Lab Invest. 2000 Aug; 80(8):1269-80. PMID: 10950118.
      View in: PubMed
    44. Greenwood-Van Meerveld B, Tyler K, Kuge T, Ogata N. Anti-diarrhoeal effects of seirogan in the rat small intestine and colon examined in vitro. Aliment Pharmacol Ther. 1999 Jan; 13(1):97-102. PMID: 9892885.
      View in: PubMed
    Greenwood-VanMeerveld's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _