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Vassilios I Sikavitsas

TitleProfessor
InstitutionUniversity of Oklahoma, Norman
DepartmentBiomedical Engineering
Address202 W. Boyd St
Norman OK
Phone(405) 325-1511
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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Krais JJ, Virani N, McKernan PH, Nguyen Q, Fung KM, Sikavitsas VI, Kurkjian CD, Harrison RG. Antitumor Synergism and Enhanced Survival with a Tumor Vasculature-Targeted Enzyme Prodrug System, Rapamycin, and Cyclophosphamide. Mol Cancer Ther. 2017 May 18. PMID: 28522586.
      View in: PubMed
    2. Engebretson B, Mussett ZR, Sikavitsas VI. The effects of varying frequency and duration of mechanical stimulation on a tissue-engineered tendon construct. Connect Tissue Res. 2017 May 01; 1-11. PMID: 28459287.
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    3. Engebretson B, Mussett ZR, Sikavitsas VI. Tenocytic extract and mechanical stimulation in a tissue-engineered tendon construct increases cellular proliferation and ECM deposition. Biotechnol J. 2017 Mar; 12(3). PMID: 28008725.
      View in: PubMed
    4. Simmons AD, Williams C, Degoix A, Sikavitsas VI. Sensing metabolites for the monitoring of tissue engineered construct cellularity in perfusion bioreactors. Biosens Bioelectron. 2017 Apr 15; 90:443-449. PMID: 27825527.
      View in: PubMed
    5. Van Rite BD, Krais JJ, Cherry M, Sikavitsas VI, Kurkjian C, Harrison RG. Antitumor activity of an enzyme prodrug therapy targeted to the breast tumor vasculature. Cancer Invest. 2013 Oct; 31(8):505-10. PMID: 24083814.
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    6. Landy BC, Vangordon SB, McFetridge PS, Sikavitsas VI, Jarman-Smith M. Mechanical and in vitro investigation of a porous PEEK foam for medical device implants. J Appl Biomater Funct Mater. 2013 Jun 24; 11(1):e35-44. PMID: 23413130.
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    7. Voronov RS, VanGordon SB, Shambaugh RL, Papavassiliou DV, Sikavitsas VI. 3D tissue-engineered construct analysis via conventional high-resolution microcomputed tomography without X-ray contrast. Tissue Eng Part C Methods. 2013 May; 19(5):327-35. PMID: 23020551.
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    8. Shi L, Brunski DB, Sikavitsas VI, Johnson MB, Striolo A. Friction coefficients for mechanically damaged bovine articular cartilage. Biotechnol Bioeng. 2012 Jul; 109(7):1769-78. PMID: 22252687.
      View in: PubMed
    9. Pham NH, Voronov RS, Vangordon SB, Sikavitsas VI, Papavassiliou DV. Predicting the stress distribution within scaffolds with ordered architecture. Biorheology. 2012; 49(4):235-47. PMID: 22836078.
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    10. Engebretson B, Sikavitsas VI. Long-term in vivo effect of PEG bone tissue engineering scaffolds. J Long Term Eff Med Implants. 2012; 22(3):211-8. PMID: 23582112.
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    11. Issa RI, Engebretson B, Rustom L, McFetridge PS, Sikavitsas VI. The effect of cell seeding density on the cellular and mechanical properties of a mechanostimulated tissue-engineered tendon. Tissue Eng Part A. 2011 Jun; 17(11-12):1479-87. PMID: 21275843.
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    12. Alvarez-Barreto JF, Landy B, VanGordon S, Place L, DeAngelis PL, Sikavitsas VI. Enhanced osteoblastic differentiation of mesenchymal stem cells seeded in RGD-functionalized PLLA scaffolds and cultured in a flow perfusion bioreactor. J Tissue Eng Regen Med. 2011 Jun; 5(6):464-75. PMID: 20878644.
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    13. Shi L, Sikavitsas VI, Striolo A. Experimental friction coefficients for bovine cartilage measured with a pin-on-disk tribometer: testing configuration and lubricant effects. Ann Biomed Eng. 2011 Jan; 39(1):132-46. PMID: 20872073.
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    14. Voronov R, Vangordon S, Sikavitsas VI, Papavassiliou DV. Computational modeling of flow-induced shear stresses within 3D salt-leached porous scaffolds imaged via micro-CT. J Biomech. 2010 May 07; 43(7):1279-86. PMID: 20185132.
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    15. Abousleiman RI, Reyes Y, McFetridge P, Sikavitsas V. Tendon tissue engineering using cell-seeded umbilical veins cultured in a mechanical stimulator. Tissue Eng Part A. 2009 Apr; 15(4):787-95. PMID: 18991488.
      View in: PubMed
    16. Abousleiman RI, Reyes Y, McFetridge P, Sikavitsas V. The human umbilical vein: a novel scaffold for musculoskeletal soft tissue regeneration. Artif Organs. 2008 Sep; 32(9):735-42. PMID: 18684203.
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    17. Castano-Izquierdo H, Alvarez-Barreto J, van den Dolder J, Jansen JA, Mikos AG, Sikavitsas VI. Pre-culture period of mesenchymal stem cells in osteogenic media influences their in vivo bone forming potential. J Biomed Mater Res A. 2007 Jul; 82(1):129-38. PMID: 17269144.
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    18. Alvarez-Barreto JF, Shreve MC, Deangelis PL, Sikavitsas VI. Preparation of a functionally flexible, three-dimensional, biomimetic poly(L-lactic acid) scaffold with improved cell adhesion. Tissue Eng. 2007 Jun; 13(6):1205-17. PMID: 17518730.
      View in: PubMed
    19. Alvarez-Barreto JF, Sikavitsas VI. Improved mesenchymal stem cell seeding on RGD-modified poly(L-lactic acid) scaffolds using flow perfusion. Macromol Biosci. 2007 May 10; 7(5):579-88. PMID: 17457938.
      View in: PubMed
    20. Alvarez-Barreto JF, Linehan SM, Shambaugh RL, Sikavitsas VI. Flow perfusion improves seeding of tissue engineering scaffolds with different architectures. Ann Biomed Eng. 2007 Mar; 35(3):429-42. PMID: 17216348.
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    21. Datta N, Pham QP, Sharma U, Sikavitsas VI, Jansen JA, Mikos AG. In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation. Proc Natl Acad Sci U S A. 2006 Feb 21; 103(8):2488-93. PMID: 16477044; PMCID: PMC1413766.
    22. Abousleiman RI, Sikavitsas VI. Bioreactors for tissues of the musculoskeletal system. Adv Exp Med Biol. 2006; 585:243-59. PMID: 17120789.
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    23. Datta N, Holtorf HL, Sikavitsas VI, Jansen JA, Mikos AG. Effect of bone extracellular matrix synthesized in vitro on the osteoblastic differentiation of marrow stromal cells. Biomaterials. 2005 Mar; 26(9):971-7. PMID: 15369685.
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    24. Sikavitsas VI, Bancroft GN, Lemoine JJ, Liebschner MA, Dauner M, Mikos AG. Flow perfusion enhances the calcified matrix deposition of marrow stromal cells in biodegradable nonwoven fiber mesh scaffolds. Ann Biomed Eng. 2005 Jan; 33(1):63-70. PMID: 15709706.
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    25. Castano H, O'Rear EA, McFetridge PS, Sikavitsas VI. Polypyrrole thin films formed by admicellar polymerization support the osteogenic differentiation of mesenchymal stem cells. Macromol Biosci. 2004 Aug 09; 4(8):785-94. PMID: 15468272.
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    26. Sikavitsas VI, van den Dolder J, Bancroft GN, Jansen JA, Mikos AG. Influence of the in vitro culture period on the in vivo performance of cell/titanium bone tissue-engineered constructs using a rat cranial critical size defect model. J Biomed Mater Res A. 2003 Dec 01; 67(3):944-51. PMID: 14613243.
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    27. Sikavitsas VI, Bancroft GN, Holtorf HL, Jansen JA, Mikos AG. Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):14683-8. PMID: 14657343; PMCID: PMC299759.
    28. Behravesh E, Sikavitsas VI, Mikos AG. Quantification of ligand surface concentration of bulk-modified biomimetic hydrogels. Biomaterials. 2003 Nov; 24(24):4365-74. PMID: 12922149.
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    29. Gomes ME, Sikavitsas VI, Behravesh E, Reis RL, Mikos AG. Effect of flow perfusion on the osteogenic differentiation of bone marrow stromal cells cultured on starch-based three-dimensional scaffolds. J Biomed Mater Res A. 2003 Oct 01; 67(1):87-95. PMID: 14517865.
      View in: PubMed
    30. van den Dolder J, Bancroft GN, Sikavitsas VI, Spauwen PH, Mikos AG, Jansen JA. Effect of fibronectin- and collagen I-coated titanium fiber mesh on proliferation and differentiation of osteogenic cells. Tissue Eng. 2003 Jun; 9(3):505-15. PMID: 12857418.
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    31. Bancroft GN, Sikavitsas VI, Mikos AG. Design of a flow perfusion bioreactor system for bone tissue-engineering applications. Tissue Eng. 2003 Jun; 9(3):549-54. PMID: 12857422.
      View in: PubMed
    32. van den Dolder J, Bancroft GN, Sikavitsas VI, Spauwen PH, Jansen JA, Mikos AG. Flow perfusion culture of marrow stromal osteoblasts in titanium fiber mesh. J Biomed Mater Res A. 2003 Feb 01; 64(2):235-41. PMID: 12522809.
      View in: PubMed
    33. Sikavitsas VI, Bancroft GN, Mikos AG. Formation of three-dimensional cell/polymer constructs for bone tissue engineering in a spinner flask and a rotating wall vessel bioreactor. J Biomed Mater Res. 2002 Oct; 62(1):136-48. PMID: 12124795.
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    34. Bancroft GN, Sikavitsas VI, van den Dolder J, Sheffield TL, Ambrose CG, Jansen JA, Mikos AG. Fluid flow increases mineralized matrix deposition in 3D perfusion culture of marrow stromal osteoblasts in a dose-dependent manner. Proc Natl Acad Sci U S A. 2002 Oct 01; 99(20):12600-5. PMID: 12242339; PMCID: PMC130506.
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