Loading...
Header Logo
Keywords
Last Name
Institution

William H Hildebrand

TitleProf,George L Cross Rsrch
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentMicrobiology & Immunology
Address975 NE 10th St
Oklahoma City OK 73104-5419
Phone405/271-1203
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. da Silva Antunes R, Pham J, McMurtrey C, Hildebrand WH, Phillips E, Mallal S, Sidney J, Busse P, Peters B, Schulten V, Sette A. Urinary Peptides As a Novel Source of T Cell Allergen Epitopes. Front Immunol. 2018; 9:886. PMID: 29755469.
      View in: PubMed
    2. DeVette CI, Andreatta M, Bardet W, Cate SJ, Jurtz VI, Jackson KW, Welm AL, Nielsen M, Hildebrand WH. NetH2pan: A Computational Tool to Guide MHC Peptide Prediction on Murine Tumors. Cancer Immunol Res. 2018 Jun; 6(6):636-644. PMID: 29615400.
      View in: PubMed
    3. Marty R, Kaabinejadian S, Rossell D, Slifker MJ, van de Haar J, Engin HB, de Prisco N, Ideker T, Hildebrand WH, Font-Burgada J, Carter H. MHC-I Genotype Restricts the Oncogenic Mutational Landscape. Cell. 2017 Nov 30; 171(6):1272-1283.e15. PMID: 29107334.
      View in: PubMed
    4. Sulzer D, Alcalay RN, Garretti F, Cote L, Kanter E, Agin-Liebes J, Liong C, McMurtrey C, Hildebrand WH, Mao X, Dawson VL, Dawson TM, Oseroff C, Pham J, Sidney J, Dillon MB, Carpenter C, Weiskopf D, Phillips E, Mallal S, Peters B, Frazier A, Arlehamn CSL, Sette A. Erratum: T cells from patients with Parkinson's disease recognize a-synuclein peptides. Nature. 2017 09 13; 549(7671):292. PMID: 28905919.
      View in: PubMed
    5. Sulzer D, Alcalay RN, Garretti F, Cote L, Kanter E, Agin-Liebes J, Liong C, McMurtrey C, Hildebrand WH, Mao X, Dawson VL, Dawson TM, Oseroff C, Pham J, Sidney J, Dillon MB, Carpenter C, Weiskopf D, Phillips E, Mallal S, Peters B, Frazier A, Lindestam Arlehamn CS, Sette A. T cells from patients with Parkinson's disease recognize a-synuclein peptides. Nature. 2017 06 29; 546(7660):656-661. PMID: 28636593.
      View in: PubMed
    6. Dulberger CL, McMurtrey CP, Hölzemer A, Neu KE, Liu V, Steinbach AM, Garcia-Beltran WF, Sulak M, Jabri B, Lynch VJ, Altfeld M, Hildebrand WH, Adams EJ. Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors. Immunity. 2017 06 20; 46(6):1018-1029.e7. PMID: 28636952.
      View in: PubMed
    7. Hilton HG, McMurtrey CP, Han AS, Djaoud Z, Guethlein LA, Blokhuis JH, Pugh JL, Goyos A, Horowitz A, Buchli R, Jackson KW, Bardet W, Bushnell DA, Robinson PJ, Mendoza JL, Birnbaum ME, Nielsen M, Garcia KC, Hildebrand WH, Parham P. The Intergenic Recombinant HLA-B*46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands. Cell Rep. 2017 05 16; 19(7):1394-1405. PMID: 28514659.
      View in: PubMed
    8. Remesh SG, Andreatta M, Ying G, Kaever T, Nielsen M, McMurtrey C, Hildebrand W, Peters B, Zajonc DM. Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT. J Biol Chem. 2017 03 31; 292(13):5262-5270. PMID: 28179428.
      View in: PubMed
    9. Greene JM, Dash P, Roy S, McMurtrey C, Awad W, Reed JS, Hammond KB, Abdulhaqq S, Wu HL, Burwitz BJ, Roth BF, Morrow DW, Ford JC, Xu G, Bae JY, Crank H, Legasse AW, Dang TH, Greenaway HY, Kurniawan M, Gold MC, Harriff MJ, Lewinsohn DA, Park BS, Axthelm MK, Stanton JJ, Hansen SG, Picker LJ, Venturi V, Hildebrand W, Thomas PG, Lewinsohn DM, Adams EJ, Sacha JB. MR1-restricted mucosal-associated invariant T (MAIT) cells respond to mycobacterial vaccination and infection in nonhuman primates. Mucosal Immunol. 2017 05; 10(3):802-813. PMID: 27759023.
      View in: PubMed
    10. Kaabinejadian S, McMurtrey CP, Kim S, Jain R, Bardet W, Schafer FB, Davenport JL, Martin AD, Diamond MS, Weidanz JA, Hansen TH, Hildebrand WH. Immunodominant West Nile Virus T Cell Epitopes Are Fewer in Number and Fashionably Late. J Immunol. 2016 05 15; 196(10):4263-73. PMID: 27183642; PMCID: PMC4874531 [Available on 05/15/17].
    11. Morozov GI, Zhao H, Mage MG, Boyd LF, Jiang J, Dolan MA, Venna R, Norcross MA, McMurtrey CP, Hildebrand W, Schuck P, Natarajan K, Margulies DH. Interaction of TAPBPR, a tapasin homolog, with MHC-I molecules promotes peptide editing. Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8):E1006-15. PMID: 26869717; PMCID: PMC4776512.
    12. Trolle T, McMurtrey CP, Sidney J, Bardet W, Osborn SC, Kaever T, Sette A, Hildebrand WH, Nielsen M, Peters B. The Length Distribution of Class I-Restricted T Cell Epitopes Is Determined by Both Peptide Supply and MHC Allele-Specific Binding Preference. J Immunol. 2016 Feb 15; 196(4):1480-7. PMID: 26783342; PMCID: PMC4744552 [Available on 02/15/17].
    13. Patterson AM, Kaabinejadian S, McMurtrey CP, Bardet W, Jackson KW, Zuna RE, Husain S, Adams GP, MacDonald G, Dillon RL, Ames H, Buchli R, Hawkins OE, Weidanz JA, Hildebrand WH. Human Leukocyte Antigen-Presented Macrophage Migration Inhibitory Factor Is a Surface Biomarker and Potential Therapeutic Target for Ovarian Cancer. Mol Cancer Ther. 2016 Feb; 15(2):313-22. PMID: 26719579; PMCID: PMC4747837 [Available on 02/01/17].
    14. Cram ED, Simmons RS, Palmer AL, Hildebrand WH, Rockey DD, Dolan BP. Enhanced Direct Major Histocompatibility Complex Class I Self-Antigen Presentation Induced by Chlamydia Infection. Infect Immun. 2016 02; 84(2):480-90. PMID: 26597986.
      View in: PubMed
    15. Abelin JG, Trantham PD, Penny SA, Patterson AM, Ward ST, Hildebrand WH, Cobbold M, Bai DL, Shabanowitz J, Hunt DF. Complementary IMAC enrichment methods for HLA-associated phosphopeptide identification by mass spectrometry. Nat Protoc. 2015 Sep; 10(9):1308-18. PMID: 26247297; PMCID: PMC4640213.
    16. Carreno BM, Magrini V, Becker-Hapak M, Kaabinejadian S, Hundal J, Petti AA, Ly A, Lie WR, Hildebrand WH, Mardis ER, Linette GP. Cancer immunotherapy. A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells. Science. 2015 May 15; 348(6236):803-8. PMID: 25837513; PMCID: PMC4549796.
    17. Yaciuk JC, Skaley M, Bardet W, Schafer F, Mojsilovic D, Cate S, Stewart CJ, McMurtrey C, Jackson KW, Buchli R, Olvera A, Cedeño S, Plana M, Mothe B, Brander C, West JT, Hildebrand WH. Direct interrogation of viral peptides presented by the class I HLA of HIV-infected T cells. J Virol. 2014 Nov; 88(22):12992-3004. PMID: 25165114; PMCID: PMC4249081.
    18. Kim S, Pinto AK, Myers NB, Hawkins O, Doll K, Kaabinejadian S, Netland J, Bevan MJ, Weidanz JA, Hildebrand WH, Diamond MS, Hansen TH. A novel T-cell receptor mimic defines dendritic cells that present an immunodominant West Nile virus epitope in mice. Eur J Immunol. 2014 Jul; 44(7):1936-46. PMID: 24723377; PMCID: PMC4107030.
    19. May NA, Wang Q, Balbo A, Konrad SL, Buchli R, Hildebrand WH, Schuck P, Hudson AW. Human herpesvirus 7 U21 tetramerizes to associate with class I major histocompatibility complex molecules. J Virol. 2014 Mar; 88(6):3298-308. PMID: 24390327; PMCID: PMC3957921.
    20. Kaabinejadian S, Piazza PA, McMurtrey CP, Vernon SR, Cate SJ, Bardet W, Schafer FB, Jackson KW, Campbell DM, Buchli R, Rinaldo CR, Hildebrand WH. Identification of class I HLA T cell control epitopes for West Nile virus. PLoS One. 2013; 8(6):e66298. PMID: 23762485; PMCID: PMC3677933.
    21. Norcross MA, Luo S, Lu L, Boyne MT, Gomarteli M, Rennels AD, Woodcock J, Margulies DH, McMurtrey C, Vernon S, Hildebrand WH, Buchli R. Abacavir induces loading of novel self-peptides into HLA-B*57: 01: an autoimmune model for HLA-associated drug hypersensitivity. AIDS. 2012 Jul 17; 26(11):F21-9. PMID: 22617051.
      View in: PubMed
    22. Li L, Kueppers F, Hildebrand W, Buchli R, Gaughan J. Elevated soluble HLA II protein levels in patients with alpha-1 antitrypsin deficiency with or without COPD. Exp Lung Res. 2012 Aug; 38(6):302-6. PMID: 22686467.
      View in: PubMed
    23. Hoof I, van Baarle D, Hildebrand WH, Kesmir C. Proteome sampling by the HLA class I antigen processing pathway. PLoS Comput Biol. 2012; 8(5):e1002517. PMID: 22615552; PMCID: PMC3355062.
    24. Sette A, Sidney J, Southwood S, Moore C, Berry J, Dow C, Bradley K, Hoof I, Lewis MG, Hildebrand WH, McMurtrey CP, Wilson NA, Watkins DI, Mothé BR. A shared MHC supertype motif emerges by convergent evolution in macaques and mice, but is totally absent in human MHC molecules. Immunogenetics. 2012 Jun; 64(6):421-34. PMID: 22322672; PMCID: PMC3349854.
    25. Mothe B, Llano A, Ibarrondo J, Daniels M, Miranda C, Zamarreño J, Bach V, Zuniga R, Pérez-Álvarez S, Berger CT, Puertas MC, Martinez-Picado J, Rolland M, Farfan M, Szinger JJ, Hildebrand WH, Yang OO, Sanchez-Merino V, Brumme CJ, Brumme ZL, Heckerman D, Allen TM, Mullins JI, Gómez G, Goulder PJ, Walker BD, Gatell JM, Clotet B, Korber BT, Sanchez J, Brander C. Definition of the viral targets of protective HIV-1-specific T cell responses. J Transl Med. 2011 Dec 07; 9:208. PMID: 22152067; PMCID: PMC3292987.
    26. Weidanz JA, Hildebrand WH. Expanding the targets available to therapeutic antibodies via novel disease-specific markers. Int Rev Immunol. 2011 Oct-Dec; 30(5-6):312-27. PMID: 22053971; PMCID: PMC3405914.
    27. Weidanz JA, Hawkins O, Verma B, Hildebrand WH. TCR-like biomolecules target peptide/MHC Class I complexes on the surface of infected and cancerous cells. Int Rev Immunol. 2011 Oct-Dec; 30(5-6):328-40. PMID: 22053972; PMCID: PMC3405915.
    28. Buranapraditkun S, Hempel U, Pitakpolrat P, Allgaier RL, Thantivorasit P, Lorenzen SI, Sirivichayakul S, Hildebrand WH, Altfeld M, Brander C, Walker BD, Phanuphak P, Hansasuta P, Rowland-Jones SL, Allen TM, Ruxrungtham K. A novel immunodominant CD8+ T cell response restricted by a common HLA-C allele targets a conserved region of Gag HIV-1 clade CRF01_AE infected Thais. PLoS One. 2011; 6(8):e23603. PMID: 21887282; PMCID: PMC3161737.
    29. Greene JM, Wiseman RW, Lank SM, Bimber BN, Karl JA, Burwitz BJ, Lhost JJ, Hawkins OE, Kunstman KJ, Broman KW, Wolinsky SM, Hildebrand WH, O'Connor DH. Differential MHC class I expression in distinct leukocyte subsets. BMC Immunol. 2011 Jul 15; 12:39. PMID: 21762519; PMCID: PMC3155488.
    30. Reed JS, Sidney J, Piaskowski SM, Glidden CE, León EJ, Burwitz BJ, Kolar HL, Eernisse CM, Furlott JR, Maness NJ, Walsh AD, Rudersdorf RA, Bardet W, McMurtrey CP, O'Connor DH, Hildebrand WH, Sette A, Watkins DI, Wilson NA. The role of MHC class I allele Mamu-A*07 during SIV(mac)239 infection. Immunogenetics. 2011 Dec; 63(12):789-807. PMID: 21732180; PMCID: PMC3706270.
    31. Hawkins O, Verma B, Lightfoot S, Jain R, Rawat A, McNair S, Caseltine S, Mojsilovic A, Gupta P, Neethling F, Almanza O, Dooley W, Hildebrand W, Weidanz J. An HLA-presented fragment of macrophage migration inhibitory factor is a therapeutic target for invasive breast cancer. J Immunol. 2011 Jun 01; 186(11):6607-16. PMID: 21515791.
      View in: PubMed
    32. Lyke KE, Fernández-Vina MA, Cao K, Hollenbach J, Coulibaly D, Kone AK, Guindo A, Burdett LA, Hartzman RJ, Wahl AR, Hildebrand WH, Doumbo OK, Plowe CV, Sztein MB. Association of HLA alleles with Plasmodium falciparum severity in Malian children. Tissue Antigens. 2011 Jun; 77(6):562-71. PMID: 21447146; PMCID: PMC3152196.
    33. Southwood S, Solomon C, Hoof I, Rudersdorf R, Sidney J, Peters B, Wahl A, Hawkins O, Hildebrand W, Mothé BR, Sette A. Functional analysis of frequently expressed Chinese rhesus macaque MHC class I molecules Mamu-A1*02601 and Mamu-B*08301 reveals HLA-A2 and HLA-A3 supertypic specificities. Immunogenetics. 2011 May; 63(5):275-90. PMID: 21274527; PMCID: PMC3068250.
    34. Budde ML, Lhost JJ, Burwitz BJ, Becker EA, Burns CM, O'Connor SL, Karl JA, Wiseman RW, Bimber BN, Zhang GL, Hildebrand W, Brusic V, O'Connor DH. Transcriptionally abundant major histocompatibility complex class I alleles are fundamental to nonhuman primate simian immunodeficiency virus-specific CD8+ T cell responses. J Virol. 2011 Apr; 85(7):3250-61. PMID: 21270169; PMCID: PMC3067831.
    35. Gleimer M, Wahl AR, Hickman HD, Abi-Rached L, Norman PJ, Guethlein LA, Hammond JA, Draghi M, Adams EJ, Juo S, Jalili R, Gharizadeh B, Ronaghi M, Garcia KC, Hildebrand WH, Parham P. Although divergent in residues of the peptide binding site, conserved chimpanzee Patr-AL and polymorphic human HLA-A*02 have overlapping peptide-binding repertoires. J Immunol. 2011 Feb 01; 186(3):1575-88. PMID: 21209280; PMCID: PMC3124313.
    36. Piazza P, McMurtrey CP, Lelic A, Cook RL, Hess R, Yablonsky E, Borowski L, Loeb MB, Bramson JL, Hildebrand WH, Rinaldo CR. Surface phenotype and functionality of WNV specific T cells differ with age and disease severity. PLoS One. 2010 Dec 13; 5(12):e15343. PMID: 21179445; PMCID: PMC3001480.
    37. Augustine AD, Cassetti MC, Ennis FA, Harris E, Hildebrand WH, Repik PM. NIAID workshop on Flavivirus immunity. Viral Immunol. 2010 Jun; 23(3):235-40. PMID: 20565288; PMCID: PMC2942861.
    38. Wang S, Buchli R, Schiller J, Gao J, VanGundy RS, Hildebrand WH, Eckels DD. Natural epitope variants of the hepatitis C virus impair cytotoxic T lymphocyte activity. World J Gastroenterol. 2010 Apr 28; 16(16):1953-69. PMID: 20419832; PMCID: PMC2860072.
    39. Kim S, Li L, McMurtrey CP, Hildebrand WH, Weidanz JA, Gillanders WE, Diamond MS, Hansen TH. Single-chain HLA-A2 MHC trimers that incorporate an immundominant peptide elicit protective T cell immunity against lethal West Nile virus infection. J Immunol. 2010 Apr 15; 184(8):4423-30. PMID: 20212098; PMCID: PMC3628725.
    40. Hurton LV, Siddik RI, Singh H, Olivares S, Rabinovich BA, Tian R, Mojsilovic D, Hildebrand W, Lee DA, Kelly SS, Champlin R, Shpall EJ, Fernandez-Viña M, Cooper LJ. Identifying candidate allogeneic NK-cell donors for hematopoietic stem-cell transplantation based on functional phenotype. Leukemia. 2010 May; 24(5):1059-62. PMID: 20164852; PMCID: PMC4135727.
    41. Wahl A, Schafer F, Bardet W, Hildebrand WH. HLA class I molecules reflect an altered host proteome after influenza virus infection. Hum Immunol. 2010 Jan; 71(1):14-22. PMID: 19748539; PMCID: PMC2795087.
    42. Fox LM, Cox DG, Lockridge JL, Wang X, Chen X, Scharf L, Trott DL, Ndonye RM, Veerapen N, Besra GS, Howell AR, Cook ME, Adams EJ, Hildebrand WH, Gumperz JE. Recognition of lyso-phospholipids by human natural killer T lymphocytes. PLoS Biol. 2009 Oct; 7(10):e1000228. PMID: 19859526; PMCID: PMC2760207.
    43. Verma B, Hawkins OE, Neethling FA, Caseltine SL, Largo SR, Hildebrand WH, Weidanz JA. Direct discovery and validation of a peptide/MHC epitope expressed in primary human breast cancer cells using a TCRm monoclonal antibody with profound antitumor properties. Cancer Immunol Immunother. 2010 Apr; 59(4):563-73. PMID: 19779714.
      View in: PubMed
    44. Wahl A, McCoy W, Schafer F, Bardet W, Buchli R, Fremont DH, Hildebrand WH. T-cell tolerance for variability in an HLA class I-presented influenza A virus epitope. J Virol. 2009 Sep; 83(18):9206-14. PMID: 19553306; PMCID: PMC2738244.
    45. Loffredo JT, Sidney J, Bean AT, Beal DR, Bardet W, Wahl A, Hawkins OE, Piaskowski S, Wilson NA, Hildebrand WH, Watkins DI, Sette A. Two MHC class I molecules associated with elite control of immunodeficiency virus replication, Mamu-B*08 and HLA-B*2705, bind peptides with sequence similarity. J Immunol. 2009 Jun 15; 182(12):7763-75. PMID: 19494300; PMCID: PMC2701622.
    46. Burwitz BJ, Pendley CJ, Greene JM, Detmer AM, Lhost JJ, Karl JA, Piaskowski SM, Rudersdorf RA, Wallace LT, Bimber BN, Loffredo JT, Cox DG, Bardet W, Hildebrand W, Wiseman RW, O'Connor SL, O'Connor DH. Mauritian cynomolgus macaques share two exceptionally common major histocompatibility complex class I alleles that restrict simian immunodeficiency virus-specific CD8+ T cells. J Virol. 2009 Jun; 83(12):6011-9. PMID: 19339351; PMCID: PMC2687399.
    47. Tuli A, Sharma M, Wang X, Simone LC, Capek HL, Cate S, Hildebrand WH, Naslavsky N, Caplan S, Solheim JC. Amyloid precursor-like protein 2 association with HLA class I molecules. Cancer Immunol Immunother. 2009 Sep; 58(9):1419-31. PMID: 19184004; PMCID: PMC2719714.
    48. Wahl A, Schafer F, Bardet W, Buchli R, Air GM, Hildebrand WH. HLA class I molecules consistently present internal influenza epitopes. Proc Natl Acad Sci U S A. 2009 Jan 13; 106(2):540-5. PMID: 19122146; PMCID: PMC2626739.
    49. Parsons R, Lelic A, Hayes L, Carter A, Marshall L, Evelegh C, Drebot M, Andonova M, McMurtrey C, Hildebrand W, Loeb MB, Bramson JL. The memory T cell response to West Nile virus in symptomatic humans following natural infection is not influenced by age and is dominated by a restricted set of CD8+ T cell epitopes. J Immunol. 2008 Jul 15; 181(2):1563-72. PMID: 18606712.
      View in: PubMed
    50. Hawkins OE, Vangundy RS, Eckerd AM, Bardet W, Buchli R, Weidanz JA, Hildebrand WH. Identification of breast cancer peptide epitopes presented by HLA-A*0201. J Proteome Res. 2008 Apr; 7(4):1445-57. PMID: 18345606.
      View in: PubMed
    51. McMurtrey CP, Lelic A, Piazza P, Chakrabarti AK, Yablonsky EJ, Wahl A, Bardet W, Eckerd A, Cook RL, Hess R, Buchli R, Loeb M, Rinaldo CR, Bramson J, Hildebrand WH. Epitope discovery in West Nile virus infection: Identification and immune recognition of viral epitopes. Proc Natl Acad Sci U S A. 2008 Feb 26; 105(8):2981-6. PMID: 18299564; PMCID: PMC2268571.
    52. Wahl A, Weidanz J, Hildebrand W. Direct class I HLA antigen discovery to distinguish virus-infected and cancerous cells. Expert Rev Proteomics. 2006 Dec; 3(6):641-52. PMID: 17181478.
      View in: PubMed
    53. Yu XG, Lichterfeld M, Chetty S, Williams KL, Mui SK, Miura T, Frahm N, Feeney ME, Tang Y, Pereyra F, Labute MX, Pfafferott K, Leslie A, Crawford H, Allgaier R, Hildebrand W, Kaslow R, Brander C, Allen TM, Rosenberg ES, Kiepiela P, Vajpayee M, Goepfert PA, Altfeld M, Goulder PJ, Walker BD. Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes. J Virol. 2007 Feb; 81(4):1619-31. PMID: 17121793; PMCID: PMC1797559.
    54. Weidanz JA, Piazza P, Hickman-Miller H, Woodburn D, Nguyen T, Wahl A, Neethling F, Chiriva-Internati M, Rinaldo CR, Hildebrand WH. Development and implementation of a direct detection, quantitation and validation system for class I MHC self-peptide epitopes. J Immunol Methods. 2007 Jan 10; 318(1-2):47-58. PMID: 17134715.
      View in: PubMed
    55. Hurley CK, Fernandez-Vina M, Hildebrand WH, Noreen HJ, Trachtenberg E, Williams TM, Baxter-Lowe LA, Begovich AB, Petersdorf E, Selvakumar A, Stastny P, Hegland J, Hartzman RJ, Carston M, Gandham S, Kollman C, Nelson G, Spellman S, Setterholm M. A high degree of HLA disparity arises from limited allelic diversity: analysis of 1775 unrelated bone marrow transplant donor-recipient pairs. Hum Immunol. 2007 Jan; 68(1):30-40. PMID: 17207710.
      View in: PubMed
    56. Weidanz JA, Nguyen T, Woodburn T, Neethling FA, Chiriva-Internati M, Hildebrand WH, Lustgarten J. Levels of specific peptide-HLA class I complex predicts tumor cell susceptibility to CTL killing. J Immunol. 2006 Oct 15; 177(8):5088-97. PMID: 17015692.
      View in: PubMed
    57. Buchli R, Vangundy RS, Giberson CF, Hildebrand WH. Critical factors in the development of fluorescence polarization-based peptide binding assays: an equilibrium study monitoring specific peptide binding to soluble HLA-A*0201. J Immunol Methods. 2006 Jul 31; 314(1-2):38-53. PMID: 16844138.
      View in: PubMed
    58. Honeyborne I, Rathod A, Buchli R, Ramduth D, Moodley E, Rathnavalu P, Chetty S, Day C, Brander C, Hildebrand W, Walker BD, Kiepiela P, Goulder PJ. Motif inference reveals optimal CTL epitopes presented by HLA class I alleles highly prevalent in southern Africa. J Immunol. 2006 Apr 15; 176(8):4699-705. PMID: 16585563.
      View in: PubMed
    59. Zuñiga R, Lucchetti A, Galvan P, Sanchez S, Sanchez C, Hernandez A, Sanchez H, Frahm N, Linde CH, Hewitt HS, Hildebrand W, Altfeld M, Allen TM, Walker BD, Korber BT, Leitner T, Sanchez J, Brander C. Relative dominance of Gag p24-specific cytotoxic T lymphocytes is associated with human immunodeficiency virus control. J Virol. 2006 Mar; 80(6):3122-5. PMID: 16501126; PMCID: PMC1395458.
    60. Loffredo JT, Sidney J, Piaskowski S, Szymanski A, Furlott J, Rudersdorf R, Reed J, Peters B, Hickman-Miller HD, Bardet W, Rehrauer WM, O'Connor DH, Wilson NA, Hildebrand WH, Sette A, Watkins DI. The high frequency Indian rhesus macaque MHC class I molecule, Mamu-B*01, does not appear to be involved in CD8+ T lymphocyte responses to SIVmac239. J Immunol. 2005 Nov 01; 175(9):5986-97. PMID: 16237093.
      View in: PubMed
    61. Ellis NM, Li Y, Hildebrand W, Fischetti VA, Cunningham MW. T cell mimicry and epitope specificity of cross-reactive T cell clones from rheumatic heart disease. J Immunol. 2005 Oct 15; 175(8):5448-56. PMID: 16210652.
      View in: PubMed
    62. Buchli R, VanGundy RS, Hickman-Miller HD, Giberson CF, Bardet W, Hildebrand WH. Development and validation of a fluorescence polarization-based competitive peptide-binding assay for HLA-A*0201--a new tool for epitope discovery. Biochemistry. 2005 Sep 20; 44(37):12491-507. PMID: 16156661.
      View in: PubMed
    63. Wren JD, Hildebrand WH, Chandrasekaran S, Melcher U. Markov model recognition and classification of DNA/protein sequences within large text databases. Bioinformatics. 2005 Nov 01; 21(21):4046-53. PMID: 16159926.
      View in: PubMed
    64. Hickman-Miller HD, Bardet W, Gilb A, Luis AD, Jackson KW, Watkins DI, Hildebrand WH. Rhesus macaque MHC class I molecules present HLA-B-like peptides. J Immunol. 2005 Jul 01; 175(1):367-75. PMID: 15972670.
      View in: PubMed
    65. Huang XL, Fan Z, Colleton BA, Buchli R, Li H, Hildebrand WH, Rinaldo CR. Processing and presentation of exogenous HLA class I peptides by dendritic cells from human immunodeficiency virus type 1-infected persons. J Virol. 2005 Mar; 79(5):3052-62. PMID: 15709025; PMCID: PMC548465.
    66. Petersen JL, Hickman-Miller HD, McIlhaney MM, Vargas SE, Purcell AW, Hildebrand WH, Solheim JC. A charged amino acid residue in the transmembrane/cytoplasmic region of tapasin influences MHC class I assembly and maturation. J Immunol. 2005 Jan 15; 174(2):962-9. PMID: 15634919.
      View in: PubMed
    67. Buchli R, VanGundy RS, Hickman-Miller HD, Giberson CF, Bardet W, Hildebrand WH. Real-time measurement of in vitro peptide binding to soluble HLA-A*0201 by fluorescence polarization. Biochemistry. 2004 Nov 23; 43(46):14852-63. PMID: 15544356.
      View in: PubMed
    68. Ellerhorst JA, Hildebrand WH, Cavett JW, Fernandez-Vina MA, Hodges S, Poindexter N, Fischer H, Grimm EA. HLA class II haplotypes predict favorable outcomes for patients with metastatic RCC. Urologe A. 2004 Sep; 43 Suppl 3:S137. PMID: 15148575.
      View in: PubMed
    69. Hickman-Miller HD, Hildebrand WH. The immune response under stress: the role of HSP-derived peptides. Trends Immunol. 2004 Aug; 25(8):427-33. PMID: 15275642.
      View in: PubMed
    70. Hickman HD, Luis AD, Buchli R, Few SR, Sathiamurthy M, VanGundy RS, Giberson CF, Hildebrand WH. Toward a definition of self: proteomic evaluation of the class I peptide repertoire. J Immunol. 2004 Mar 01; 172(5):2944-52. PMID: 14978097.
      View in: PubMed
    71. Leffell MS, Fallin MD, Hildebrand WH, Cavett JW, Iglehart BA, Zachary AA. HLA alleles and haplotypes among the Lakota Sioux: report of the ASHI minority workshops, part III. Hum Immunol. 2004 Jan; 65(1):78-89. PMID: 14700599.
      View in: PubMed
    72. Hickman HD, Luis AD, Bardet W, Buchli R, Battson CL, Shearer MH, Jackson KW, Kennedy RC, Hildebrand WH. Cutting edge: class I presentation of host peptides following HIV infection. J Immunol. 2003 Jul 01; 171(1):22-6. PMID: 12816978.
      View in: PubMed
    73. Ellerhorst JA, Hildebrand WH, Cavett JW, Fernandez-Vina MA, Hodges S, Poindexter N, Fischer H, Grimm EA. Heterozygosity or homozygosity for 2 HLA class II haplotypes predict favorable outcomes for renal cell carcinoma treated with cytokine therapy. J Urol. 2003 Jun; 169(6):2084-8. PMID: 12771724.
      View in: PubMed
    74. Sathiamurthy M, Hickman HD, Cavett JW, Zahoor A, Prilliman K, Metcalf S, Fernandez Vina M, Hildebrand WH. Population of the HLA ligand database. Tissue Antigens. 2003 Jan; 61(1):12-9. PMID: 12622773.
      View in: PubMed
    75. Huang XL, Fan Z, Zheng L, Borowski L, Li H, Thomas EK, Hildebrand WH, Zhao XQ, Rinaldo CR. Priming of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cell responses by dendritic cells loaded with HIV-1 proteins. J Infect Dis. 2003 Jan 15; 187(2):315-9. PMID: 12552458.
      View in: PubMed
    76. Vogel TU, Friedrich TC, O'Connor DH, Rehrauer W, Dodds EJ, Hickman H, Hildebrand W, Sidney J, Sette A, Hughes A, Horton H, Vielhuber K, Rudersdorf R, De Souza IP, Reynolds MR, Allen TM, Wilson N, Watkins DI. Escape in one of two cytotoxic T-lymphocyte epitopes bound by a high-frequency major histocompatibility complex class I molecule, Mamu-A*02: a paradigm for virus evolution and persistence? J Virol. 2002 Nov; 76(22):11623-36. PMID: 12388723; PMCID: PMC136802.
    77. Leffell MS, Fallin MD, Erlich HA, Fernandez-Vina M, Hildebrand WH, Mack SJ, Zachary AA. HLA antigens, alleles and haplotypes among the Yup'ik Alaska natives: report of the ASHI Minority Workshops, Part II. Hum Immunol. 2002 Jul; 63(7):614-25. PMID: 12072196.
      View in: PubMed
    78. Wang QJ, Huang XL, Rappocciolo G, Jenkins FJ, Hildebrand WH, Fan Z, Thomas EK, Rinaldo CR. Identification of an HLA A*0201-restricted CD8(+) T-cell epitope for the glycoprotein B homolog of human herpesvirus 8. Blood. 2002 May 01; 99(9):3360-6. PMID: 11964304.
      View in: PubMed
    79. Hildebrand WH, Turnquist HR, Prilliman KR, Hickman HD, Schenk EL, McIlhaney MM, Solheim JC. HLA class I polymorphism has a dual impact on ligand binding and chaperone interaction. Hum Immunol. 2002 Apr; 63(4):248-55. PMID: 12039406.
      View in: PubMed
    80. Turnquist HR, Schenk EL, McIlhaney MM, Hickman HD, Hildebrand WH, Solheim JC. Disparate binding of chaperone proteins by HLA-A subtypes. Immunogenetics. 2002 Feb; 53(10-11):830-4. PMID: 11862383.
      View in: PubMed
    81. Wu S, Shiao YM, Lai SM, Lai CY, Chen SP, Chen YF, Sidebottom DA, Hildebrand WH, Chou FC, Tsai MF. New DR5 sequences: a novel DRB1*11122 allele identified in Paiwan tribe members of Taiwan and a corrected sequence for the DRB1*1201 allele. Tissue Antigens. 2001 Sep; 58(3):193-7. PMID: 11703830.
      View in: PubMed
    82. Ellexson-Turner ME, Leffell MS, Zachary AA, Turner S, Bennett T, Sidebottom DA, Cao K, Fernández-Viña M, Hildebrand WH. Sequence-based typing of HLA class I alleles in Alaskan Yupik Eskimo. Hum Immunol. 2001 Jun; 62(6):639-44. PMID: 11390039.
      View in: PubMed
    83. Wu S, Shiao YM, Lai CY, Lai SM, Chen SP, Sidebottom DA, Hildebrand WH, Tilanus MG, Chou FC, Tsai MF. Polymorphism of human HLA-DRB1 antigens generated by genetic exchange between DR2 (DRB1*15011) and DR6 (DRB1*1405) alleles: a novel DRB1 allele (DRB1*1437) identified in a Paiwan tribe member of Taiwan. Tissue Antigens. 2001 Apr; 57(4):384-7. PMID: 11380954.
      View in: PubMed
    84. Urvater JA, Hickman H, Dzuris JL, Prilliman K, Allen TM, Schwartz KJ, Lorentzen D, Shufflebotham C, Collins EJ, Neiffer DL, Raphael B, Hildebrand W, Sette A, Watkins DI. Gorillas with spondyloarthropathies express an MHC class I molecule with only limited sequence similarity to HLA-B27 that binds peptides with arginine at P2. J Immunol. 2001 Mar 01; 166(5):3334-44. PMID: 11207289.
      View in: PubMed
    85. Hickman HD, Cavett JW, Ellexson-Turner ME, Sparkman JN, Bennett TT, Turner S, Sidebottom DA, Trachtenberg EA, Confer DL, Hildebrand WH. Non-conservative substitutions distinguish previously uncharacterized HLA-A molecules. Tissue Antigens. 2001 Feb; 57(2):95-102. PMID: 11260503.
      View in: PubMed
    86. Ellexson-Turner M, Sidebottom D, Turner S, Bennett T, Hildebrand WH. Precision genotyping of human leukocyte antigen-A, -B and -C loci via direct DNA sequencing. Methods Mol Biol. 2001; 156:129-42. PMID: 11068755.
      View in: PubMed
    87. Hickman HD, Batson CL, Prilliman KR, Crawford DL, Jackson KL, Hildebrand WH. C-terminal epitope tagging facilitates comparative ligand mapping from MHC class I positive cells. Hum Immunol. 2000 Dec; 61(12):1339-46. PMID: 11163091.
      View in: PubMed
    88. Turnquist HR, Thomas HJ, Prilliman KR, Lutz CT, Hildebrand WH, Solheim JC. HLA-B polymorphism affects interactions with multiple endoplasmic reticulum proteins. Eur J Immunol. 2000 Oct; 30(10):3021-8. PMID: 11069086.
      View in: PubMed
    89. Rinaldo CR, Huang XL, Fan Z, Margolick JB, Borowski L, Hoji A, Kalinyak C, McMahon DK, Riddler SA, Hildebrand WH, Day RB, Mellors JW. Anti-human immunodeficiency virus type 1 (HIV-1) CD8(+) T-lymphocyte reactivity during combination antiretroviral therapy in HIV-1-infected patients with advanced immunodeficiency. J Virol. 2000 May; 74(9):4127-38. PMID: 10756025; PMCID: PMC111927.
    90. Prilliman KR, Crawford D, Hickman HD, Jackson KW, Wang J, Hildebrand WH. Alpha-2 domain polymorphism and HLA class I peptide loading. Tissue Antigens. 1999 Nov; 54(5):450-60. PMID: 10599884.
      View in: PubMed
    91. Prilliman KR, Jackson KW, Lindsey M, Wang J, Crawford D, Hildebrand WH. HLA-B15 peptide ligands are preferentially anchored at their C termini. J Immunol. 1999 Jun 15; 162(12):7277-84. PMID: 10358176.
      View in: PubMed
    92. Prilliman KR, Lindsey M, Wang J, Jackson KW, Hildebrand WH. Peptide motif of the class I molecule HLA-B*1503. Immunogenetics. 1999 Feb; 49(2):144-6. PMID: 9887352.
      View in: PubMed
    93. Turner S, Ellexson ME, Hickman HD, Sidebottom DA, Fernández-Viña M, Confer DL, Hildebrand WH. Sequence-based typing provides a new look at HLA-C diversity. J Immunol. 1998 Aug 01; 161(3):1406-13. PMID: 9686604.
      View in: PubMed
    94. Ellexson ME, Peck RL, Stewart D, Keller J, Hildebrand WH. Characterization of an HLA-A26 serologic variant. Immunogenetics. 1998 Jul; 48(2):152-5. PMID: 9634481.
      View in: PubMed
    95. Prilliman KR, Lindsey M, Jackson KW, Cole J, Bonner R, Hildebrand WH. Complexity among constituents of the HLA-B*1501 peptide motif. Immunogenetics. 1998 Jul; 48(2):89-97. PMID: 9634472.
      View in: PubMed
    96. Ellexson M, Lai-Kwan P, Lau M, Muto K, Terasaki P, Cole J, Thompson C, Hildebrand W. Polymorphism at codons 114, 116, 145, and 163 muddle the typing of HLA-B*1304. Hum Immunol. 1997 Jun; 55(1):66-73. PMID: 9328792.
      View in: PubMed
    97. Kennedy RC, Shearer MH, Hildebrand W. Nonhuman primate models to evaluate vaccine safety and immunogenicity. Vaccine. 1997 Jun; 15(8):903-8. PMID: 9234544.
      View in: PubMed
    98. Prilliman K, Lindsey M, Zuo Y, Jackson KW, Zhang Y, Hildebrand W. Large-scale production of class I bound peptides: assigning a signature to HLA-B*1501. Immunogenetics. 1997; 45(6):379-85. PMID: 9089095.
      View in: PubMed
    99. Ellexson M, Stewart D, Chrétien P, Zhang L, Hildebrand W. Description of a modified sequencing strategy and the molecular characterization of HLA-B*8201. Tissue Antigens. 1996 May; 47(5):438-41. PMID: 8795148.
      View in: PubMed
    100. Chandanayingyong D, Adams EJ, Arnett KL, Hildebrand WH, Parham P, Lau M. The presence of HLA-A*2403 and HLA-B*1512 on the same haplotype in a Thai family. Tissue Antigens. 1996 May; 47(5):426-7. PMID: 8795144.
      View in: PubMed
    101. Prilliman K, Lawlor D, Ellexson M, McElwee N, Confer D, Cooper DK, Kennedy RC, Hildebrand W. Characterization of baboon class I major histocompatibility molecules. Implications for baboon-to-human xenotransplantation. Transplantation. 1996 Apr 15; 61(7):989-96. PMID: 8623205.
      View in: PubMed
    102. Prilliman K, Steiner N, Ellexson M, Stewart D, Lau M, Terasaki P, Hurley C, Hildebrand W. Novel alleles HLA-B*7802 and B*51022: evidence for convergency in the HLA-B5 family. Tissue Antigens. 1996 Jan; 47(1):49-57. PMID: 8929712.
      View in: PubMed
    103. Ellexson M, Lau M, Terasaki P, Hildebrand W. Molecular characterization of HLA-A*6803. Immunogenetics. 1996; 45(1):78-9. PMID: 8881043.
      View in: PubMed
    104. Parham P, Arnett KL, Adams EJ, Barber LD, Domena JD, Stewart D, Hildebrand WH, Little AM. The HLA-B73 antigen has a most unusual structure that defines a second lineage of HLA-B alleles. Tissue Antigens. 1994 May; 43(5):302-13. PMID: 7524186.
      View in: PubMed
    105. Hildebrand WH, Domena JD, Shen SY, Lau M, Terasaki PI, Bunce M, Marsh SG, Guttridge MG, Bias WB, Parham P. HLA-B15: a widespread and diverse family of HLA-B alleles. Tissue Antigens. 1994 Apr; 43(4):209-18. PMID: 7521976.
      View in: PubMed
    106. Little AM, Domena JD, Hildebrand WH, Shen SY, Barber LD, Marsh SG, Bias WB, Parham P. HLA-B67: a member of the HLA-B16 family that expresses the ME1 epitope. Tissue Antigens. 1994 Jan; 43(1):38-43. PMID: 7517584.
      View in: PubMed
    107. Domena JD, Little AM, Madrigal AJ, Hildebrand WH, Johnston-Dow L, du Toit E, Bias WB, Parham P. Structural heterogeneity in HLA-B70, a high-frequency antigen of black populations. Tissue Antigens. 1993 Nov; 42(5):509-17. PMID: 8146861.
      View in: PubMed
    108. Domena JD, Hildebrand WH, Bias WB, Parham P. A sixth family of HLA-A alleles defined by HLA-A*8001. Tissue Antigens. 1993 Sep; 42(3):156-9. PMID: 8284791.
      View in: PubMed
    109. Hildebrand WH, Domena JD, Parham P. Primary structure shows HLA-B59 to be a hybrid of HLA-B55 and HLA-B51, and not a subtype of HLA-B8. Tissue Antigens. 1993 Apr; 41(4):190-5. PMID: 8362411.
      View in: PubMed
    110. Madrigal JA, Hildebrand WH, Belich MP, Benjamin RJ, Little AM, Zemmour J, Ennis PD, Ward FE, Petzl-Erler ML, du Toit ED, et al. Structural diversity in the HLA-A10 family of alleles: correlations with serology. Tissue Antigens. 1993 Feb; 41(2):72-80. PMID: 8475492.
      View in: PubMed
    111. Hildebrand WH, Madrigal JA, Belich MP, Zemmour J, Ward FE, Williams RC, Parham P. Serologic cross-reactivities poorly reflect allelic relationships in the HLA-B12 and HLA-B21 groups. Dominant epitopes of the alpha 2 helix. J Immunol. 1992 Dec 01; 149(11):3563-8. PMID: 1385528.
      View in: PubMed
    112. Madrigal JA, Belich MP, Hildebrand WH, Benjamin RJ, Little AM, Zemmour J, Ennis PD, Ward FE, Petzl-Erler ML, du Toit ED, et al. Distinctive HLA-A,B antigens of black populations formed by interallelic conversion. J Immunol. 1992 Nov 15; 149(10):3411-5. PMID: 1431115.
      View in: PubMed
    113. Belich MP, Madrigal JA, Hildebrand WH, Zemmour J, Williams RC, Luz R, Petzl-Erler ML, Parham P. Unusual HLA-B alleles in two tribes of Brazilian Indians. Nature. 1992 May 28; 357(6376):326-9. PMID: 1317015.
      View in: PubMed
    114. Zemmour J, Gumperz JE, Hildebrand WH, Ward FE, Marsh SG, Williams RC, Parham P. The molecular basis for reactivity of anti-Cw1 and anti-Cw3 alloantisera with HLA-B46 haplotypes. Tissue Antigens. 1992 May; 39(5):249-57. PMID: 1384166.
      View in: PubMed
    115. Hildebrand WH, Madrigal JA, Little AM, Parham P. HLA-Bw22: a family of molecules with identity to HLA-B7 in the alpha 1-helix. J Immunol. 1992 Feb 15; 148(4):1155-62. PMID: 1737933.
      View in: PubMed
    116. Kawaguchi G, Hildebrand WH, Hiraiwa M, Karaki S, Nagao T, Akiyama N, Uchida H, Kashiwase K, Akaza T, Williams RC, et al. Two subtypes of HLA-B51 differing by substitution at position 171 of the alpha 2 helix. Immunogenetics. 1992; 37(1):57-63. PMID: 1428012.
      View in: PubMed
    117. Hildebrand WH, Horton RM, Pease LR, Martinko JM. Nucleotide sequence analysis of H-2Df and the spontaneous in vivo H-2Dfm2 mutation. Mol Immunol. 1992 Jan; 29(1):61-9. PMID: 1731192.
      View in: PubMed
    118. Madrigal JA, Belich MP, Benjamin RJ, Little AM, Hildebrand WH, Mann DL, Parham P. Molecular definition of a polymorphic antigen (LA45) of free HLA-A and -B heavy chains found on the surfaces of activated B and T cells. J Exp Med. 1991 Nov 01; 174(5):1085-95. PMID: 1940790; PMCID: PMC2119017.
    119. Rubocki RJ, Connolly JM, Hansen TH, Melvold RW, Kim BS, Hildebrand WH, Martinko J. Mutation at amino acid position 133 of H-2Dd prevents beta 2m association and immune recognition but not surface expression. J Immunol. 1991 Apr 01; 146(7):2352-7. PMID: 2005403.
      View in: PubMed
    120. Horton RM, Hildebrand WH, Martinko JM, Pease LR. Structural analysis of H-2Kf and H-2Kfm1 by using H-2K locus-specific sequences. J Immunol. 1990 Sep 15; 145(6):1782-7. PMID: 2391419.
      View in: PubMed
    Hildebrand's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _