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William Lovallo

TitleProf
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentPsychiatry & Behavioral Sci
Phone405/456-3124
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    Collapse Research 
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    R01AA019691     (LOVALLO, WILLIAM R)Dec 2, 2010 - Nov 30, 2014
    NIH/NIAAA
    Neuroimaging in the Oklahoma Family Health Patterns Project
    Role: Principal Investigator
    I01CX000252     (LOVALLO, WILLIAM R)Apr 1, 2010 - Mar 31, 2014
    VA
    Neuroimaging in the Oklahoma Family Health Patterns Project
    Role: Principal Investigator
    R01AA012207     (LOVALLO, WILLIAM R)Sep 30, 2001 - Apr 30, 2019
    NIH/NIAAA
    Oklahoma Family Health Patterns: A Study Across Generations
    Role: Principal Investigator
    T32HL007640     (LOVALLO, WILLIAM R)Jul 1, 1991 - Jun 30, 2004
    NIH/NHLBI
    BEHAVIORAL MEDICINE: CARDIOVASCULAR DISEASE RESEARCH
    Role: Principal Investigator
    R01HL032050     (LOVALLO, WILLIAM R)Dec 1, 1984 - Jun 30, 2006
    NIH/NHLBI
    CAFFEINE INFLUENCES ON EXERCISE AND PSYCHOLOGICAL STRESS
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Lovallo WR, Acheson A, Cohoon AJ, Sorocco KH, Vincent AS, Hodgkinson CA, Goldman D. Working memory reflects vulnerability to early life adversity as a risk factor for substance use disorder in the FKBP5 cortisol cochaperone polymorphism, rs9296158. PLoS One. 2019; 14(6):e0218212. PMID: 31185043.
      View in: PubMed
    2. Lovallo WR, Cohoon AJ, Sorocco KH, Vincent AS, Acheson A, Hodgkinson CA, Goldman D. Early-Life Adversity and Blunted Stress Reactivity as Predictors of Alcohol and Drug use in Persons With COMT (rs4680) Val158Met Genotypes. Alcohol Clin Exp Res. 2019 Jul; 43(7):1519-1527. PMID: 31150143.
      View in: PubMed
    3. Lovallo WR, Cohoon AJ, Acheson A, Vincent AS, Sorocco KH. Cortisol stress reactivity in women, diurnal variations, and hormonal contraceptives: studies from the Family Health Patterns Project. Stress. 2019 Jul; 22(4):421-427. PMID: 30896268.
      View in: PubMed
    4. Acheson A, Vincent AS, Cohoon A, Lovallo WR. Early life adversity and increased delay discounting: Findings from the Family Health Patterns project. Exp Clin Psychopharmacol. 2019 Apr; 27(2):153-159. PMID: 30556730.
      View in: PubMed
    5. Lovallo WR, Cohoon AJ, Acheson A, Sorocco KH, Vincent AS. Blunted stress reactivity reveals vulnerability to early life adversity in young adults with a family history of alcoholism. Addiction. 2018 Nov 21. PMID: 30461123.
      View in: PubMed
    6. Lovallo WR, Acheson A, Vincent AS, Sorocco KH, Cohoon AJ. Early life adversity diminishes the cortisol response to opioid blockade in women: Studies from the Family Health Patterns project. PLoS One. 2018; 13(10):e0205723. PMID: 30312327.
      View in: PubMed
    7. Buchanan TW, Lovallo WR. The role of genetics in stress effects on health and addiction. Curr Opin Psychol. 2019 Jun; 27:72-76. PMID: 30292777.
      View in: PubMed
    8. Hawkins MAW, Colaizzi J, Gunstad J, Hughes JW, Mullins LL, Betts N, Smith CE, Keirns NG, Vohs KD, Moore SM, Forman EM, Lovallo WR. Cognitive and Self-regulatory Mechanisms of Obesity Study (COSMOS): Study protocol for a randomized controlled weight loss trial examining change in biomarkers, cognition, and self-regulation across two behavioral treatments. Contemp Clin Trials. 2018 03; 66:20-27. PMID: 29274893.
      View in: PubMed
    9. Acheson A, Vincent AS, Cohoon AJ, Lovallo WR. Defining the phenotype of young adults with family histories of alcohol and other substance use disorders: Studies from the family health patterns project. Addict Behav. 2018 Feb; 77:247-254. PMID: 29107202.
      View in: PubMed
    10. Lovallo WR, Enoch MA, Sorocco KH, Vincent AS, Acheson A, Cohoon AJ, Hodgkinson CA, Goldman D. Joint Impact of Early Life Adversity and COMT Val158Met (rs4680) Genotypes on the Adult Cortisol Response to Psychological Stress. Psychosom Med. 2017 Jul/Aug; 79(6):631-637. PMID: 28452825.
      View in: PubMed
    11. Carroll D, Ginty AT, Whittaker AC, Lovallo WR, de Rooij SR. The behavioural, cognitive, and neural corollaries of blunted cardiovascular and cortisol reactions to acute psychological stress. Neurosci Biobehav Rev. 2017 06; 77:74-86. PMID: 28254428.
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    12. Lovallo WR, Enoch MA, Acheson A, Cohoon AJ, Sorocco KH, Hodgkinson CA, Vincent AS, Goldman D. Early-Life Adversity Interacts with FKBP5 Genotypes: Altered Working Memory and Cardiac Stress Reactivity in the Oklahoma Family Health Patterns Project. Neuropsychopharmacology. 2016 06; 41(7):1724-32. PMID: 26632991.
      View in: PubMed
    13. Lovallo WR, Enoch MA, Acheson A, Cohoon AJ, Sorocco KH, Hodgkinson CA, Vincent AS, Glahn DC, Goldman D. Cortisol Stress Response in Men and Women Modulated Differentially by the Mu-Opioid Receptor Gene Polymorphism OPRM1 A118G. Neuropsychopharmacology. 2015 Oct; 40(11):2546-54. PMID: 25881118.
      View in: PubMed
    14. Lovallo WR. Can exaggerated stress reactivity and prolonged recovery predict negative health outcomes? The case of cardiovascular disease. Psychosom Med. 2015 Apr; 77(3):212-4. PMID: 25829241.
      View in: PubMed
    15. Sorocco KH, Carnes NC, Cohoon AJ, Vincent AS, Lovallo WR. Risk factors for alcoholism in the Oklahoma Family Health Patterns project: impact of early life adversity and family history on affect regulation and personality. Drug Alcohol Depend. 2015 May 01; 150:38-45. PMID: 25813267.
      View in: PubMed
    16. Dager AD, McKay DR, Kent JW, Curran JE, Knowles E, Sprooten E, Göring HH, Dyer TD, Pearlson GD, Olvera RL, Fox PT, Lovallo WR, Duggirala R, Almasy L, Blangero J, Glahn DC. Shared genetic factors influence amygdala volumes and risk for alcoholism. Neuropsychopharmacology. 2015 Jan; 40(2):412-20. PMID: 25079289.
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    17. Acheson A, Wijtenburg SA, Rowland LM, Bray BC, Gaston F, Mathias CW, Fox PT, Lovallo WR, Wright SN, Hong LE, McGuire S, Kochunov P, Dougherty DM. Combining diffusion tensor imaging and magnetic resonance spectroscopy to study reduced frontal white matter integrity in youths with family histories of substance use disorders. Hum Brain Mapp. 2014 Dec; 35(12):5877-87. PMID: 25044331.
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    18. Acheson A, Wijtenburg SA, Rowland LM, Winkler AM, Gaston F, Mathias CW, Fox PT, Lovallo WR, Wright SN, Hong LE, Dougherty DM, Kochunov P. Assessment of whole brain white matter integrity in youths and young adults with a family history of substance-use disorders. Hum Brain Mapp. 2014 Nov; 35(11):5401-13. PMID: 24867528.
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    19. Acheson A, Franklin C, Cohoon AJ, Glahn DC, Fox PT, Lovallo WR. Anomalous temporoparietal activity in individuals with a family history of alcoholism: studies from the Oklahoma Family Health Patterns Project. Alcohol Clin Exp Res. 2014 Jun; 38(6):1639-45. PMID: 24848358.
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    20. Lovallo WR, Enoch MA, Yechiam E, Glahn DC, Acheson A, Sorocco KH, Hodgkinson CA, Kim B, Cohoon AJ, Vincent AS, Goldman D. Differential impact of serotonin transporter activity on temperament and behavior in persons with a family history of alcoholism in the Oklahoma Family Health Patterns Project. Alcohol Clin Exp Res. 2014 Jun; 38(6):1575-81. PMID: 24796636.
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    21. Roche DJ, King AC, Cohoon AJ, Lovallo WR. Hormonal contraceptive use diminishes salivary cortisol response to psychosocial stress and naltrexone in healthy women. Pharmacol Biochem Behav. 2013 Aug; 109:84-90. PMID: 23672966.
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    22. Lovallo WR, Farag NH, Sorocco KH, Acheson A, Cohoon AJ, Vincent AS. Early life adversity contributes to impaired cognition and impulsive behavior: studies from the Oklahoma Family Health Patterns Project. Alcohol Clin Exp Res. 2013 Apr; 37(4):616-23. PMID: 23126641.
      View in: PubMed
    23. Lovallo WR. Early life adversity reduces stress reactivity and enhances impulsive behavior: implications for health behaviors. Int J Psychophysiol. 2013 Oct; 90(1):8-16. PMID: 23085387.
      View in: PubMed
    24. Lovallo WR, King AC, Farag NH, Sorocco KH, Cohoon AJ, Vincent AS. Naltrexone effects on cortisol secretion in women and men in relation to a family history of alcoholism: studies from the Oklahoma Family Health Patterns Project. Psychoneuroendocrinology. 2012 Dec; 37(12):1922-8. PMID: 22575355.
      View in: PubMed
    25. Robinson JL, Laird AR, Glahn DC, Blangero J, Sanghera MK, Pessoa L, Fox PM, Uecker A, Friehs G, Young KA, Griffin JL, Lovallo WR, Fox PT. The functional connectivity of the human caudate: an application of meta-analytic connectivity modeling with behavioral filtering. Neuroimage. 2012 Mar; 60(1):117-29. PMID: 22197743.
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    26. Lovallo WR, Farag NH, Sorocco KH, Cohoon AJ, Vincent AS. Lifetime adversity leads to blunted stress axis reactivity: studies from the Oklahoma Family Health Patterns Project. Biol Psychiatry. 2012 Feb 15; 71(4):344-9. PMID: 22112928.
      View in: PubMed
    27. Acheson A, Vincent AS, Sorocco KH, Lovallo WR. Greater discounting of delayed rewards in young adults with family histories of alcohol and drug use disorders: studies from the Oklahoma family health patterns project. Alcohol Clin Exp Res. 2011 Sep; 35(9):1607-13. PMID: 21599715.
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    28. Miller MW, McKinney AE, Kanter FS, Korte KJ, Lovallo WR. Hydrocortisone suppression of the fear-potentiated startle response and posttraumatic stress disorder. Psychoneuroendocrinology. 2011 Aug; 36(7):970-80. PMID: 21269779.
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    29. Farag NH, Whitsett TL, McKey BS, Wilson MF, Vincent AS, Everson-Rose SA, Lovallo WR. Caffeine and blood pressure response: sex, age, and hormonal status. J Womens Health (Larchmt). 2010 Jun; 19(6):1171-6. PMID: 20500126.
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    30. Lovallo WR, Farag NH, Vincent AS. Use of a resting control day in measuring the cortisol response to mental stress: diurnal patterns, time of day, and gender effects. Psychoneuroendocrinology. 2010 Sep; 35(8):1253-8. PMID: 20233640.
      View in: PubMed
    31. Lovallo WR. Cardiovascular responses to stress and disease outcomes: a test of the reactivity hypothesis. Hypertension. 2010 Apr; 55(4):842-3. PMID: 20194293.
      View in: PubMed
    32. Robinson JL, Laird AR, Glahn DC, Lovallo WR, Fox PT. Metaanalytic connectivity modeling: delineating the functional connectivity of the human amygdala. Hum Brain Mapp. 2010 Feb; 31(2):173-84. PMID: 19603407.
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    33. Lovallo WR. Do low levels of stress reactivity signal poor states of health? Biol Psychol. 2011 Feb; 86(2):121-8. PMID: 20079397.
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    34. Lovallo WR, Robinson JL, Glahn DC, Fox PT. Acute effects of hydrocortisone on the human brain: an fMRI study. Psychoneuroendocrinology. 2010 Jan; 35(1):15-20. PMID: 19836143.
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    35. Sorocco KH, Monnot M, Vincent AS, Ross ED, Lovallo WR. Deficits in affective prosody comprehension: family history of alcoholism versus alcohol exposure. Alcohol Alcohol. 2010 Jan-Feb; 45(1):25-9. PMID: 19820001.
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    36. Miranda R, MacKillop J, Meyerson LA, Justus A, Lovallo WR. Influence of antisocial and psychopathic traits on decision-making biases in alcoholics. Alcohol Clin Exp Res. 2009 May; 33(5):817-25. PMID: 19298325.
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    37. Lovallo WR, List JA. The IRB is key. Science. 2009 Feb 06; 323(5915):713-4; author reply 713-4. PMID: 19197040.
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    38. Lane RD, Waldstein SR, Critchley HD, Derbyshire SW, Drossman DA, Wager TD, Schneiderman N, Chesney MA, Jennings JR, Lovallo WR, Rose RM, Thayer JF, Cameron OG. The rebirth of neuroscience in psychosomatic medicine, Part II: clinical applications and implications for research. Psychosom Med. 2009 Feb; 71(2):135-51. PMID: 19196806.
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    39. Lane RD, Waldstein SR, Chesney MA, Jennings JR, Lovallo WR, Kozel PJ, Rose RM, Drossman DA, Schneiderman N, Thayer JF, Cameron OG. The rebirth of neuroscience in psychosomatic medicine, Part I: historical context, methods, and relevant basic science. Psychosom Med. 2009 Feb; 71(2):117-34. PMID: 19196808.
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    40. Farag NH, Moore WE, Lovallo WR, Mills PJ, Khandrika S, Eichner JE. Hypothalamic-pituitary-adrenal axis function: relative contributions of perceived stress and obesity in women. J Womens Health (Larchmt). 2008 Dec; 17(10):1647-55. PMID: 19049359.
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    41. Acheson A, Robinson JL, Glahn DC, Lovallo WR, Fox PT. Differential activation of the anterior cingulate cortex and caudate nucleus during a gambling simulation in persons with a family history of alcoholism: studies from the Oklahoma Family Health Patterns Project. Drug Alcohol Depend. 2009 Feb 01; 100(1-2):17-23. PMID: 19026496.
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    42. Saunders B, Farag N, Vincent AS, Collins FL, Sorocco KH, Lovallo WR. Impulsive errors on a Go-NoGo reaction time task: disinhibitory traits in relation to a family history of alcoholism. Alcohol Clin Exp Res. 2008 May; 32(5):888-94. PMID: 18373725.
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    43. Abrantes-Pais Fde N, Friedman JK, Lovallo WR, Ross ED. Psychological or physiological: why are tetraplegic patients content? Neurology. 2007 Jul 17; 69(3):261-7. PMID: 17460156.
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    44. Glahn DC, Lovallo WR, Fox PT. Reduced amygdala activation in young adults at high risk of alcoholism: studies from the Oklahoma family health patterns project. Biol Psychiatry. 2007 Jun 01; 61(11):1306-9. PMID: 17306772.
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    45. Rashid A, Hines M, Scherlag BJ, Yamanashi WS, Lovallo W. The effects of caffeine on the inducibility of atrial fibrillation. J Electrocardiol. 2006 Oct; 39(4):421-5. PMID: 16919674.
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    46. Farag NH, Vincent AS, McKey BS, Al'Absi M, Whitsett TL, Lovallo WR. Sex differences in the hemodynamic responses to mental stress: Effect of caffeine consumption. Psychophysiology. 2006 Jul; 43(4):337-43. PMID: 16916429.
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    47. Lovallo WR, Farag NH, Vincent AS, Thomas TL, Wilson MF. Cortisol responses to mental stress, exercise, and meals following caffeine intake in men and women. Pharmacol Biochem Behav. 2006 Mar; 83(3):441-7. PMID: 16631247.
      View in: PubMed
    48. Lovallo WR, Yechiam E, Sorocco KH, Vincent AS, Collins FL. Working memory and decision-making biases in young adults with a family history of alcoholism: studies from the Oklahoma family health patterns project. Alcohol Clin Exp Res. 2006 May; 30(5):763-73. PMID: 16634844.
      View in: PubMed
    49. Sorocco KH, Vincent AS, Collins FL, Johnson CA, Lovallo WR. Recruitment of healthy participants for studies on risks for alcoholism: effectiveness of random digit dialling. Alcohol Alcohol. 2006 May-Jun; 41(3):349-52. PMID: 16551752.
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    50. Lovallo WR. Cortisol secretion patterns in addiction and addiction risk. Int J Psychophysiol. 2006 Mar; 59(3):195-202. PMID: 16434116.
      View in: PubMed
    51. Lovallo WR. The hypothalamic-pituitary-adrenocortical axis in addiction. Int J Psychophysiol. 2006 Mar; 59(3):193-4. PMID: 16430982.
      View in: PubMed
    52. Sorocco KH, Lovallo WR, Vincent AS, Collins FL. Blunted hypothalamic-pituitary-adrenocortical axis responsivity to stress in persons with a family history of alcoholism. Int J Psychophysiol. 2006 Mar; 59(3):210-7. PMID: 16360227.
      View in: PubMed
    53. Lovallo WR. Cardiovascular reactivity: mechanisms and pathways to cardiovascular disease. Int J Psychophysiol. 2005 Nov-Dec; 58(2-3):119-32. PMID: 16150506.
      View in: PubMed
    54. Lovallo WR, Whitsett TL, al'Absi M, Sung BH, Vincent AS, Wilson MF. Caffeine stimulation of cortisol secretion across the waking hours in relation to caffeine intake levels. Psychosom Med. 2005 Sep-Oct; 67(5):734-9. PMID: 16204431.
      View in: PubMed
    55. Farag NH, Vincent AS, McKey BS, Whitsett TL, Lovallo WR. Hemodynamic mechanisms underlying the incomplete tolerance to caffeine's pressor effects. Am J Cardiol. 2005 Jun 01; 95(11):1389-92. PMID: 15904654.
      View in: PubMed
    56. Farag NH, Vincent AS, Sung BH, Whitsett TL, Wilson MF, Lovallo WR. Caffeine tolerance is incomplete: persistent blood pressure responses in the ambulatory setting. Am J Hypertens. 2005 May; 18(5 Pt 1):714-9. PMID: 15882556.
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    57. Hartley TR, Lovallo WR, Whitsett TL. Cardiovascular effects of caffeine in men and women. Am J Cardiol. 2004 Apr 15; 93(8):1022-6. PMID: 15081447.
      View in: PubMed
    58. Lovallo WR, Wilson MF, Vincent AS, Sung BH, McKey BS, Whitsett TL. Blood pressure response to caffeine shows incomplete tolerance after short-term regular consumption. Hypertension. 2004 Apr; 43(4):760-5. PMID: 14967827.
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    59. Miranda R, Meyerson LA, Myers RR, Lovallo WR. Altered affective modulation of the startle reflex in alcoholics with antisocial personality disorder. Alcohol Clin Exp Res. 2003 Dec; 27(12):1901-11. PMID: 14691377.
      View in: PubMed
    60. Bernardy NC, King AC, Lovallo WR. Cardiovascular responses to physical and psychological stress in female alcoholics with transitory hypertension after early abstinence. Alcohol Clin Exp Res. 2003 Sep; 27(9):1489-98. PMID: 14506411.
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    61. Lovallo WR, Whitsett TL, Wilson MF. caffeine and coffee tolerance. Circulation. 2003 Aug 12; 108(6):e38-40; author reply e38-40. PMID: 12914010.
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    62. Kamarck TW, Lovallo WR. Cardiovascular reactivity to psychological challenge: conceptual and measurement considerations. Psychosom Med. 2003 Jan-Feb; 65(1):9-21. PMID: 12554812.
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    63. Lovallo WR, Gerin W. Psychophysiological reactivity: mechanisms and pathways to cardiovascular disease. Psychosom Med. 2003 Jan-Feb; 65(1):36-45. PMID: 12554814.
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    64. Errico AL, King AC, Lovallo WR, Parsons OA. Cortisol dysregulation and cognitive impairment in abstinent male alcoholics. Alcohol Clin Exp Res. 2002 Aug; 26(8):1198-204. PMID: 12198394.
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    65. Panknin TL, Dickensheets SL, Nixon SJ, Lovallo WR. Attenuated heart rate responses to public speaking in individuals with alcohol dependence. Alcohol Clin Exp Res. 2002 Jun; 26(6):841-7. PMID: 12068253.
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    66. Powell LH, Lovallo WR, Matthews KA, Meyer P, Midgley AR, Baum A, Stone AA, Underwood L, McCann JJ, Janikula Herro K, Ory MG. Physiologic markers of chronic stress in premenopausal, middle-aged women. Psychosom Med. 2002 May-Jun; 64(3):502-9. PMID: 12021424.
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    67. Kosslyn SM, Cacioppo JT, Davidson RJ, Hugdahl K, Lovallo WR, Spiegel D, Rose R. Bridging psychology and biology. The analysis of individuals in groups. Am Psychol. 2002 May; 57(5):341-51. PMID: 12025764.
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    68. Miranda R, Meyerson LA, Buchanan TW, Lovallo WR. Altered emotion-modulated startle in young adults with a family history of alcoholism. Alcohol Clin Exp Res. 2002 Apr; 26(4):441-8. PMID: 11981118.
      View in: PubMed
    69. Monnot M, Lovallo WR, Nixon SJ, Ross E. Neurological basis of deficits in affective prosody comprehension among alcoholics and fetal alcohol-exposed adults. J Neuropsychiatry Clin Neurosci. 2002; 14(3):321-8. PMID: 12154157.
      View in: PubMed
    70. al'Absi M, Hugdahl K, Lovallo WR. Adrenocortical stress responses and altered working memory performance. Psychophysiology. 2002 Jan; 39(1):95-9. PMID: 12206301.
      View in: PubMed
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