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Allan F Wiechmann

TitleAssociate Professor
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentCell Biology
Address940 Stanton L Young Blvd
Oklahoma City OK 73104-5020
Phone405/271-8001
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    Collapse Research 
    Collapse research activities and funding
    F32EY005859     (WIECHMANN, ALLAN F)Oct 21, 1985
    NIH/NEI
    THE ROLE OF MELATONIN IN RETINAL METABOLISM
    Role: Principal Investigator

    R29EY008006     (WIECHMANN, ALLAN F)May 1, 1988 - Apr 30, 1993
    NIH/NEI
    REGULATION AND FUNCTION OF MELATONIN IN THE RETINA
    Role: Principal Investigator

    R01EY010081     (WIECHMANN, ALLAN F)May 1, 1993 - Apr 30, 2000
    NIH/NEI
    EXPRESSION OF RECOVERIN IN THE RETINA
    Role: Principal Investigator

    R03EY013686     (WIECHMANN, ALLAN F)Feb 7, 2002 - Aug 31, 2006
    NIH/NEI
    Retinal Circadian Signaling in a Transgenic Model
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Harper AR, Wiechmann AF, Moiseyev G, Ma JX, Summers JA. Identification of active retinaldehyde dehydrogenase isoforms in the postnatal human eye. PLoS One. 2015; 10(3):e0122008. PMID: 25793304; PMCID: PMC4368790.
    2. Wiechmann AF, Ceresa BP, Howard EW. Diurnal variation of tight junction integrity associates inversely with matrix metalloproteinase expression in Xenopus laevis corneal epithelium: implications for circadian regulation of homeostatic surface cell desquamation. PLoS One. 2014; 9(11):e113810. PMID: 25412440; PMCID: PMC4239109.
    3. Wiechmann AF, Sherry DM. Role of melatonin and its receptors in the vertebrate retina. Int Rev Cell Mol Biol. 2013; 300:211-42. PMID: 23273863.
      View in: PubMed
    4. Wiechmann AF, Sherry DM. Melatonin receptors are anatomically organized to modulate transmission specifically to cone pathways in the retina of Xenopus laevis. J Comp Neurol. 2012 Apr 15; 520(6):1115-27. PMID: 22020534; PMCID: PMC4300947.
    5. Fung KM, Hassell LA, Talbert ML, Wiechmann AF, Chaser BE, Ramey J. Whole slide images and digital media in pathology education, testing, and practice: the Oklahoma experience. Anal Cell Pathol (Amst). 2012; 35(1):37-40. PMID: 21965282; PMCID: PMC4605706.
    6. Rada JA, Wiechmann AF, Hollaway LR, Baggenstoss BA, Weigel PH. Increased hyaluronan synthase-2 mRNA expression and hyaluronan accumulation with choroidal thickening: response during recovery from induced myopia. Invest Ophthalmol Vis Sci. 2010 Dec; 51(12):6172-9. PMID: 20574026; PMCID: PMC3055751.
    7. Huang Z, Anderson RE, Cao W, Wiechmann AF, Rajala RV. Light-induced tyrosine phosphorylation of rod outer segment membrane proteins regulate the translocation, membrane binding and activation of type II a phosphatidylinositol-5-phosphate 4-kinase. Neurochem Res. 2011 Apr; 36(4):627-35. PMID: 20204506; PMCID: PMC4227407.
    8. Wiechmann AF, Hollaway LR, Rada JA. Melatonin receptor expression in Xenopus laevis surface corneal epithelium: diurnal rhythm of lateral membrane localization. Mol Vis. 2009 Nov 17; 15:2384-403. PMID: 19936310; PMCID: PMC2779068.
    9. Rada JA, Wiechmann AF. Ocular expression of avian thymic hormone: changes during the recovery from induced myopia. Mol Vis. 2009; 15:778-92. PMID: 19390653; PMCID: PMC2671582.
    10. Li G, Rajala A, Wiechmann AF, Anderson RE, Rajala RV. Activation and membrane binding of retinal protein kinase Balpha/Akt1 is regulated through light-dependent generation of phosphoinositides. J Neurochem. 2008 Dec; 107(5):1382-97. PMID: 18823366; PMCID: PMC2596869.
    11. Plafker KS, Farjo KM, Wiechmann AF, Plafker SM. The human ubiquitin conjugating enzyme, UBE2E3, is required for proliferation of retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2008 Dec; 49(12):5611-8. PMID: 18614808; PMCID: PMC2610360.
    12. Wiechmann AF, Summers JA. Circadian rhythms in the eye: the physiological significance of melatonin receptors in ocular tissues. Prog Retin Eye Res. 2008 Mar; 27(2):137-60. PMID: 18316227.
      View in: PubMed
    13. Wiechmann AF, Chignell CF, Roberts JE. Influence of dietary melatonin on photoreceptor survival in the rat retina: an ocular toxicity study. Exp Eye Res. 2008 Feb; 86(2):241-50. PMID: 18078931; PMCID: PMC2377032.
    14. Rada JA, Wiechmann AF. Melatonin receptors in chick ocular tissues: implications for a role of melatonin in ocular growth regulation. Invest Ophthalmol Vis Sci. 2006 Jan; 47(1):25-33. PMID: 16384940.
      View in: PubMed
    15. Prada C, Udin SB, Wiechmann AF, Zhdanova IV. Stimulation of melatonin receptors decreases calcium levels in xenopus tectal cells by activating GABA(C) receptors. J Neurophysiol. 2005 Aug; 94(2):968-78. PMID: 15817645.
      View in: PubMed
    16. Wiechmann AF, Udin SB, Summers Rada JA. Localization of Mel1b melatonin receptor-like immunoreactivity in ocular tissues of Xenopus laevis. Exp Eye Res. 2004 Oct; 79(4):585-94. PMID: 15381042.
      View in: PubMed
    17. Wiechmann AF, Vrieze MJ, Dighe R, Hu Y. Direct modulation of rod photoreceptor responsiveness through a Mel(1c) melatonin receptor in transgenic Xenopus laevis retina. Invest Ophthalmol Vis Sci. 2003 Oct; 44(10):4522-31. PMID: 14507901.
      View in: PubMed
    18. Wiechmann AF, Rada JA. Melatonin receptor expression in the cornea and sclera. Exp Eye Res. 2003 Aug; 77(2):219-25. PMID: 12873453.
      View in: PubMed
    19. Wiechmann AF, Vrieze MJ, Wirsig-Wiechmann CR. Differential distribution of melatonin receptors in the pituitary gland of Xenopus laevis. Anat Embryol (Berl). 2003 Mar; 206(4):291-9. PMID: 12649727.
      View in: PubMed
    20. Wiechmann A, Howard E. Functional analysis of the human recoverin gene promoter. Curr Eye Res. 2003 Jan; 26(1):25-32. PMID: 12789533.
      View in: PubMed
    21. Wiechmann AF. Differential distribution of Mel(1a) and Mel(1c) melatonin receptors in Xenopus laevis retina. Exp Eye Res. 2003 Jan; 76(1):99-106. PMID: 12589779.
      View in: PubMed
    22. Wiechmann AF. Regulation of gene expression by melatonin: a microarray survey of the rat retina. J Pineal Res. 2002 Oct; 33(3):178-85. PMID: 12220334.
      View in: PubMed
    23. Wirsig-Wiechmann CR, Wiechmann AF. Vole retina is a target for gonadotropin-releasing hormone. Brain Res. 2002 Sep 20; 950(1-2):210-7. PMID: 12231246.
      View in: PubMed
    24. Wiechmann AF, Komori N, Matsumoto H. Melatonin induces alterations in protein expression in the Xenopus laevis retina. J Pineal Res. 2002 May; 32(4):270-4. PMID: 11982798.
      View in: PubMed
    25. Thompson AM, Wiechmann AF. 5-HT(1A) receptor subtype mRNA expression in cochlear nucleus. Hear Res. 2002 Feb; 164(1-2):77-81. PMID: 11950527.
      View in: PubMed
    26. Wirsig-Wiechmann CR, Wiechmann AF, Eisthen HL. What defines the nervus terminalis? Neurochemical, developmental, and anatomical criteria. Prog Brain Res. 2002; 141:45-58. PMID: 12508560.
      View in: PubMed
    27. Wiechmann AF, Wirsig-Wiechmann CR. Melatonin receptor mRNA and protein expression in Xenopus laevis nonpigmented ciliary epithelial cells. Exp Eye Res. 2001 Nov; 73(5):617-23. PMID: 11747362.
      View in: PubMed
    28. Wiechmann AF, Wirsig-Wiechmann CR. Multiple cell targets for melatonin action in Xenopus laevis retina: distribution of melatonin receptor immunoreactivity. Vis Neurosci. 2001 Sep-Oct; 18(5):695-702. PMID: 11925005.
      View in: PubMed
    29. Wiechmann AF, Smith AR. Melatonin receptor RNA is expressed in photoreceptors and displays a diurnal rhythm in Xenopus retina. Brain Res Mol Brain Res. 2001 Jul 13; 91(1-2):104-11. PMID: 11457497.
      View in: PubMed
    30. Wiechmann AF, Burden MA. Regulation of AA-NAT and HIOMT gene expression by butyrate and cyclic AMP in Y79 human retinoblastoma cells. J Pineal Res. 1999 Sep; 27(2):116-21. PMID: 10496148.
      View in: PubMed
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