Loading...
Header Logo
Keywords
Last Name
Institution

Dimitrios Karamichos

TitleProf,Asoc
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentOphthalmology
Phone405/271-4019
vCardDownload vCard

    Collapse Biography 
    Collapse education and training
    Imperial College, London, UKMsc2002Engineering and Physical Sciences in Medicine
    University College London, London, UKPhD2006Tissue Engineering/Molecular Biology
    University College London, London, UKFellow2006Novel Spectroscopic Technique
    UT SouthwesternFellow2008Human Cornea Tissue Engineering

    Collapse Research 
    Collapse research activities and funding
    R01EY031316     (MANDAL, NAWAJES)Jul 1, 2020 - May 31, 2024
    NIH/NEI
    Sphingolipids and their Impact in Corneal Wound Healing
    Role: Co-Principal Investigator

    R01EY030028     (KARAMICHOS, DIMITRIOS)Sep 30, 2019 - Jun 30, 2024
    NIH/NEI
    Utility of PIP as a Novel Keratoconus Biomarker
    Role: Principal Investigator

    R01EY028949     (KARAMICHOS, DIMITRIOS)Sep 1, 2018 - Aug 31, 2021
    NIH/NEI
    A Novel Pathogenic Pathway for Diabetic Keratopathy
    Role: Principal Investigator

    R01EY028888     (KARAMICHOS, DIMITRIOS)May 1, 2018 - Apr 30, 2021
    NIH/NEI
    Sex Hormones and Keratoconus
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. McKay TB, Hutcheon AEK, Guo X, Zieske JD, Karamichos D. Modeling the cornea in 3-dimensions: Current and future perspectives. Exp Eye Res. 2020 Jun 30; 108127. PMID: 32619578.
      View in: PubMed
    2. McKay TB, Serjersen H, Hjortdal J, Zieske JD, Karamichos D. Characterization of Tear Immunoglobulins in a Small-Cohort of Keratoconus Patients. Sci Rep. 2020 Jun 10; 10(1):9426. PMID: 32523038.
      View in: PubMed
    3. Matlock HG, Qiu F, Malechka V, Zhou K, Cheng R, Benyajati S, Whelchel A, Karamichos D, Ma JX. Pathogenic Role of PPARa Downregulation in Corneal Nerve Degeneration and Impaired Corneal Sensitivity in Diabetes. Diabetes. 2020 Jun; 69(6):1279-1291. PMID: 32213513.
      View in: PubMed
    4. Karamichos D. A New Era for Analytical Cellular Pathology. Anal Cell Pathol (Amst). 2020; 2020:8502160. PMID: 32399390.
      View in: PubMed
    5. McKay TB, Karamichos D, Hutcheon AEK, Guo X, Zieske JD. Corneal Epithelial-Stromal Fibroblast Constructs to Study Cell-Cell Communication in Vitro. Bioengineering (Basel). 2019 Dec 04; 6(4). PMID: 31817298.
      View in: PubMed
    6. Karamichos D, Barrientez B, Nicholas S, Ma S, Van L, Bak-Nielsen S, Hjortdal J. Gonadotropins in Keratoconus: The Unexpected Suspects. Cells. 2019 11 22; 8(12). PMID: 31766771.
      View in: PubMed
    7. McKay TB, Priyadarsini S, Karamichos D. Mechanisms of Collagen Crosslinking in Diabetes and Keratoconus. Cells. 2019 10 11; 8(10). PMID: 31614631.
      View in: PubMed
    8. Whelchel AE, McKay TB, Priyadarsini S, Rowsey T, Karamichos D. Association between Diabetes and Keratoconus: A Retrospective Analysis. Sci Rep. 2019 09 24; 9(1):13808. PMID: 31551458.
      View in: PubMed
    9. Sharif R, Khaled ML, McKay TB, Liu Y, Karamichos D. Transcriptional profiling of corneal stromal cells derived from patients with keratoconus. Sci Rep. 2019 08 29; 9(1):12567. PMID: 31467338.
      View in: PubMed
    10. Barrientez B, Nicholas SE, Whelchel A, Sharif R, Hjortdal J, Karamichos D. Corneal injury: Clinical and molecular aspects. Exp Eye Res. 2019 09; 186:107709. PMID: 31238077.
      View in: PubMed
    11. Sharif R, Bak-Nielsen S, Sejersen H, Ding K, Hjortdal J, Karamichos D. Prolactin-Induced Protein is a novel biomarker for Keratoconus. Exp Eye Res. 2019 02; 179:55-63. PMID: 30393162.
      View in: PubMed
    12. Sharif R, Fowler B, Karamichos D. Collagen cross-linking impact on keratoconus extracellular matrix. PLoS One. 2018; 13(7):e0200704. PMID: 30020979.
      View in: PubMed
    13. Sharif R, Bak-Nielsen S, Hjortdal J, Karamichos D. Pathogenesis of Keratoconus: The intriguing therapeutic potential of Prolactin-inducible protein. Prog Retin Eye Res. 2018 11; 67:150-167. PMID: 29758268.
      View in: PubMed
    14. Sharif R, Sejersen H, Frank G, Hjortdal J, Karamichos D. Effects of collagen cross-linking on the keratoconus metabolic network. Eye (Lond). 2018 07; 32(7):1271-1281. PMID: 29576618.
      View in: PubMed
    15. Lee A, Karamichos D, Onochie OE, Hutcheon AEK, Rich CB, Zieske JD, Trinkaus-Randall V. Hypoxia modulates the development of a corneal stromal matrix model. Exp Eye Res. 2018 05; 170:127-137. PMID: 29496505.
      View in: PubMed
    16. Sharif R, Priyadarsini S, Rowsey TG, Ma JX, Karamichos D. Corneal Tissue Engineering: An In Vitro Model of the Stromal-nerve Interactions of the Human Cornea. J Vis Exp. 2018 01 24; (131). PMID: 29443018.
      View in: PubMed
    17. Priyadarsini S, Nicholas SE, Karamichos D. 3D Stacked Construct: A Novel Substitute for Corneal Tissue Engineering. Methods Mol Biol. 2018; 1697:173-180. PMID: 28451994.
      View in: PubMed
    18. Sharif R, Hjortdal J, Sejersen H, Frank G, Karamichos D. Human in vitro Model Reveals the Effects of Collagen Cross-linking on Keratoconus Pathogenesis. Sci Rep. 2017 10 02; 7(1):12517. PMID: 28970517.
      View in: PubMed
    19. Nicholas SE, Rowsey TG, Priyadarsini S, Mandal NA, Karamichos D. Unravelling the interplay of sphingolipids and TGF-ß signaling in the human corneal stroma. PLoS One. 2017; 12(8):e0182390. PMID: 28806736.
      View in: PubMed
    20. Rowsey TG, Karamichos D. The role of lipids in corneal diseases and dystrophies: a systematic review. Clin Transl Med. 2017 Dec; 6(1):30. PMID: 28782089.
      View in: PubMed
    21. Priyadarsini S, Rowsey TG, Ma JX, Karamichos D. Unravelling the stromal-nerve interactions in the human diabetic cornea. Exp Eye Res. 2017 11; 164:22-30. PMID: 28827027.
      View in: PubMed
    22. McKay TB, Hjortdal J, Priyadarsini S, Karamichos D. Acute hypoxia influences collagen and matrix metalloproteinase expression by human keratoconus cells in vitro. PLoS One. 2017; 12(4):e0176017. PMID: 28426715.
      View in: PubMed
    23. McKay TB, Hjortdal J, Sejersen H, Karamichos D. Differential Effects of Hormones on Cellular Metabolism in Keratoconus In Vitro. Sci Rep. 2017 02 17; 7:42896. PMID: 28211546.
      View in: PubMed
    24. Qi H, Priyadarsini S, Nicholas SE, Sarker-Nag A, Allegood J, Chalfant CE, Mandal NA, Karamichos D. Analysis of sphingolipids in human corneal fibroblasts from normal and keratoconus patients. J Lipid Res. 2017 04; 58(4):636-648. PMID: 28188148.
      View in: PubMed
    25. McKay TB, Karamichos D. Quercetin and the ocular surface: What we know and where we are going. Exp Biol Med (Maywood). 2017 03; 242(6):565-572. PMID: 28056553.
      View in: PubMed
    26. Betensley A, Sharif R, Karamichos D. A Systematic Review of the Role of Dysfunctional Wound Healing in the Pathogenesis and Treatment of Idiopathic Pulmonary Fibrosis. J Clin Med. 2016 Dec 26; 6(1). PMID: 28035951.
      View in: PubMed
    27. Priyadarsini S, Sarker-Nag A, Rowsey TG, Ma JX, Karamichos D. Establishment of a 3D In Vitro Model to Accelerate the Development of Human Therapies against Corneal Diabetes. PLoS One. 2016; 11(12):e0168845. PMID: 28005998.
      View in: PubMed
    28. He M, Storr-Paulsen T, Wang AL, Ghezzi CE, Wang S, Fullana M, Karamichos D, Utheim TP, Islam R, Griffith M, Islam MM, Hodges RR, Wnek GE, Kaplan DL, Dartt DA. Artificial Polymeric Scaffolds as Extracellular Matrix Substitutes for Autologous Conjunctival Goblet Cell Expansion. Invest Ophthalmol Vis Sci. 2016 Nov 01; 57(14):6134-6146. PMID: 27832279.
      View in: PubMed
    29. Priyadarsini S, McKay TB, Sarker-Nag A, Allegood J, Chalfant C, Ma JX, Karamichos D. Complete metabolome and lipidome analysis reveals novel biomarkers in the human diabetic corneal stroma. Exp Eye Res. 2016 Dec; 153:90-100. PMID: 27742548.
      View in: PubMed
    30. Zareian R, Susilo ME, Paten JA, McLean JP, Hollmann J, Karamichos D, Messer CS, Tambe DT, Saeidi N, Zieske JD, Ruberti JW. Human Corneal Fibroblast Pattern Evolution and Matrix Synthesis on Mechanically Biased Substrates. Tissue Eng Part A. 2016 10; 22(19-20):1204-1217. PMID: 27600605.
      View in: PubMed
    31. McKay TB, Hjortdal J, Sejersen H, Asara JM, Wu J, Karamichos D. Endocrine and Metabolic Pathways Linked to Keratoconus: Implications for the Role of Hormones in the Stromal Microenvironment. Sci Rep. 2016 05 09; 6:25534. PMID: 27157003.
      View in: PubMed
    32. Vieira-Potter VJ, Karamichos D, Lee DJ. Ocular Complications of Diabetes and Therapeutic Approaches. Biomed Res Int. 2016; 2016:3801570. PMID: 27119078.
      View in: PubMed
    33. Sarker-Nag A, Hutcheon AE, Karamichos D. Mitochondrial Profile and Responses to TGF-ß Ligands in Keratoconus. Curr Eye Res. 2016 07; 41(7):900-7. PMID: 26430764.
      View in: PubMed
    34. McKay TB, Sarker-Nag A, Lyon D, Asara JM, Karamichos D. Quercetin modulates keratoconus metabolism in vitro. Cell Biochem Funct. 2015 Jul; 33(5):341-50. PMID: 26173740.
      View in: PubMed
    35. Lyon D', McKay TB, Sarkar-Nag A, Priyadarsini S, Karamichos D. Human Keratoconus Cell Contractility is Mediated by Transforming Growth Factor-Beta Isoforms. J Funct Biomater. 2015 Jun 18; 6(2):422-38. PMID: 26096146.
      View in: PubMed
    36. Drevets P, Chucair-Elliott A, Shrestha P, Jinkins J, Karamichos D, Carr DJ. The use of human cornea organotypic cultures to study herpes simplex virus type 1 (HSV-1)-induced inflammation. Graefes Arch Clin Exp Ophthalmol. 2015 Oct; 253(10):1721-8. PMID: 26047535.
      View in: PubMed
    37. Priyadarsini S, McKay TB, Sarker-Nag A, Karamichos D. Keratoconus in vitro and the key players of the TGF-ß pathway. Mol Vis. 2015; 21:577-88. PMID: 26015770.
      View in: PubMed
    38. Karamichos D. Ocular tissue engineering: current and future directions. J Funct Biomater. 2015 Feb 17; 6(1):77-80. PMID: 25695336.
      View in: PubMed
    39. Karamichos D, Zieske JD, Sejersen H, Sarker-Nag A, Asara JM, Hjortdal J. Tear metabolite changes in keratoconus. Exp Eye Res. 2015 Mar; 132:1-8. PMID: 25579606.
      View in: PubMed
    40. Priyadarsini S, Sarker-Nag A, Allegood J, Chalfant C, Karamichos D. Description of the sphingolipid content and subspecies in the diabetic cornea. Curr Eye Res. 2015; 40(12):1204-10. PMID: 25426847.
      View in: PubMed
    41. Priyadarsini S, Hjortdal J, Sarker-Nag A, Sejersen H, Asara JM, Karamichos D. Gross cystic disease fluid protein-15/prolactin-inducible protein as a biomarker for keratoconus disease. PLoS One. 2014; 9(11):e113310. PMID: 25405607.
      View in: PubMed
    42. Karamichos D, Hjortdal J. Keratoconus: tissue engineering and biomaterials. J Funct Biomater. 2014 Sep 11; 5(3):111-34. PMID: 25215423.
      View in: PubMed
    43. Karamichos D. Keratoconus: In Vitro and In Vivo. Jacobs J Ophthalmol. 2015 Sep; 1(1). PMID: 30101209.
      View in: PubMed
    44. Karamichos D, Hutcheon AE, Zieske JD. Reversal of fibrosis by TGF-ß3 in a 3D in vitro model. Exp Eye Res. 2014 Jul; 124:31-6. PMID: 24800655.
      View in: PubMed
    45. Karamichos D, Funderburgh ML, Hutcheon AE, Zieske JD, Du Y, Wu J, Funderburgh JL. A role for topographic cues in the organization of collagenous matrix by corneal fibroblasts and stem cells. PLoS One. 2014; 9(1):e86260. PMID: 24465995.
      View in: PubMed
    46. Karamichos D, Rich CB, Zareian R, Hutcheon AE, Ruberti JW, Trinkaus-Randall V, Zieske JD. TGF-ß3 stimulates stromal matrix assembly by human corneal keratocyte-like cells. Invest Ophthalmol Vis Sci. 2013 Oct 09; 54(10):6612-9. PMID: 24022012.
      View in: PubMed
    47. Karamichos D, Zareian R, Guo X, Hutcheon AE, Ruberti JW, Zieske JD. Novel in Vitro Model for Keratoconus Disease. J Funct Biomater. 2012 Nov 13; 3(4):760-775. PMID: 23888249.
      View in: PubMed
    48. Karamichos D, Rich CB, Hutcheon AE, Ren R, Saitta B, Trinkaus-Randall V, Zieske JD. Self-assembled matrix by umbilical cord stem cells. J Funct Biomater. 2011 Sep 01; 2(3):213-29. PMID: 24956304.
      View in: PubMed
    Karamichos's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description