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Last Name

Dimitrios Karamichos

InstitutionUniversity of Oklahoma Health Sciences Center
Address608 Stanton L Young Blvd
Oklahoma City OK 73104-5104
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    Collapse Biography 
    Collapse education and training
    Imperial College, London, UKMsc2002Engineering and Physical Sciences in Medicine
    University College London, London, UKPhD2006Tissue Engineering/Molecular Biology
    University College London, London, UKFellow2006Novel Spectroscopic Technique
    UT SouthwesternFellow2008Human Cornea Tissue Engineering

    Collapse Research 
    Collapse research activities and funding
    R01EY028888     (KARAMICHOS, DIMITRIOS)May 1, 2018 - Apr 30, 2021
    Sex Hormones and Keratoconus
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Sharif R, Bak-Nielsen S, Hjortdal J, Karamichos D. Pathogenesis of Keratoconus: The intriguing therapeutic potential of Prolactin-inducible protein. Prog Retin Eye Res. 2018 Nov; 67:150-167. PMID: 29758268.
      View in: PubMed
    2. Sharif R, Sejersen H, Frank G, Hjortdal J, Karamichos D. Effects of collagen cross-linking on the keratoconus metabolic network. Eye (Lond). 2018 07; 32(7):1271-1281. PMID: 29576618.
      View in: PubMed
    3. Lee A, Karamichos D, Onochie OE, Hutcheon AEK, Rich CB, Zieske JD, Trinkaus-Randall V. Hypoxia modulates the development of a corneal stromal matrix model. Exp Eye Res. 2018 05; 170:127-137. PMID: 29496505.
      View in: PubMed
    4. Sharif R, Priyadarsini S, Rowsey TG, Ma JX, Karamichos D. Corneal Tissue Engineering: An In Vitro Model of the Stromal-nerve Interactions of the Human Cornea. J Vis Exp. 2018 01 24; (131). PMID: 29443018.
      View in: PubMed
    5. Priyadarsini S, Nicholas SE, Karamichos D. 3D Stacked Construct: A Novel Substitute for Corneal Tissue Engineering. Methods Mol Biol. 2018; 1697:173-180. PMID: 28451994.
      View in: PubMed
    6. Sharif R, Hjortdal J, Sejersen H, Frank G, Karamichos D. Human in vitro Model Reveals the Effects of Collagen Cross-linking on Keratoconus Pathogenesis. Sci Rep. 2017 Oct 02; 7(1):12517. PMID: 28970517.
      View in: PubMed
    7. Nicholas SE, Rowsey TG, Priyadarsini S, Mandal NA, Karamichos D. Unravelling the interplay of sphingolipids and TGF-ß signaling in the human corneal stroma. PLoS One. 2017; 12(8):e0182390. PMID: 28806736.
      View in: PubMed
    8. Rowsey TG, Karamichos D. The role of lipids in corneal diseases and dystrophies: a systematic review. Clin Transl Med. 2017 Dec; 6(1):30. PMID: 28782089.
      View in: PubMed
    9. Priyadarsini S, Rowsey TG, Ma JX, Karamichos D. Unravelling the stromal-nerve interactions in the human diabetic cornea. Exp Eye Res. 2017 11; 164:22-30. PMID: 28827027.
      View in: PubMed
    10. McKay TB, Hjortdal J, Priyadarsini S, Karamichos D. Acute hypoxia influences collagen and matrix metalloproteinase expression by human keratoconus cells in vitro. PLoS One. 2017; 12(4):e0176017. PMID: 28426715.
      View in: PubMed
    11. McKay TB, Hjortdal J, Sejersen H, Karamichos D. Differential Effects of Hormones on Cellular Metabolism in Keratoconus In Vitro. Sci Rep. 2017 02 17; 7:42896. PMID: 28211546.
      View in: PubMed
    12. Qi H, Priyadarsini S, Nicholas SE, Sarker-Nag A, Allegood J, Chalfant CE, Mandal NA, Karamichos D. Analysis of sphingolipids in human corneal fibroblasts from normal and keratoconus patients. J Lipid Res. 2017 04; 58(4):636-648. PMID: 28188148.
      View in: PubMed
    13. McKay TB, Karamichos D. Quercetin and the ocular surface: What we know and where we are going. Exp Biol Med (Maywood). 2017 03; 242(6):565-572. PMID: 28056553.
      View in: PubMed
    14. Betensley A, Sharif R, Karamichos D. A Systematic Review of the Role of Dysfunctional Wound Healing in the Pathogenesis and Treatment of Idiopathic Pulmonary Fibrosis. J Clin Med. 2016 Dec 26; 6(1). PMID: 28035951.
      View in: PubMed
    15. Priyadarsini S, Sarker-Nag A, Rowsey TG, Ma JX, Karamichos D. Establishment of a 3D In Vitro Model to Accelerate the Development of Human Therapies against Corneal Diabetes. PLoS One. 2016; 11(12):e0168845. PMID: 28005998.
      View in: PubMed
    16. He M, Storr-Paulsen T, Wang AL, Ghezzi CE, Wang S, Fullana M, Karamichos D, Utheim TP, Islam R, Griffith M, Islam MM, Hodges RR, Wnek GE, Kaplan DL, Dartt DA. Artificial Polymeric Scaffolds as Extracellular Matrix Substitutes for Autologous Conjunctival Goblet Cell Expansion. Invest Ophthalmol Vis Sci. 2016 Nov 01; 57(14):6134-6146. PMID: 27832279.
      View in: PubMed
    17. Priyadarsini S, McKay TB, Sarker-Nag A, Allegood J, Chalfant C, Ma JX, Karamichos D. Complete metabolome and lipidome analysis reveals novel biomarkers in the human diabetic corneal stroma. Exp Eye Res. 2016 Dec; 153:90-100. PMID: 27742548.
      View in: PubMed
    18. Zareian R, Susilo ME, Paten JA, McLean JP, Hollmann J, Karamichos D, Messer CS, Tambe DT, Saeidi N, Zieske JD, Ruberti JW. Human Corneal Fibroblast Pattern Evolution and Matrix Synthesis on Mechanically Biased Substrates. Tissue Eng Part A. 2016 10; 22(19-20):1204-1217. PMID: 27600605.
      View in: PubMed
    19. McKay TB, Hjortdal J, Sejersen H, Asara JM, Wu J, Karamichos D. Endocrine and Metabolic Pathways Linked to Keratoconus: Implications for the Role of Hormones in the Stromal Microenvironment. Sci Rep. 2016 05 09; 6:25534. PMID: 27157003; PMCID: PMC4860577.
    20. Vieira-Potter VJ, Karamichos D, Lee DJ. Ocular Complications of Diabetes and Therapeutic Approaches. Biomed Res Int. 2016; 2016:3801570. PMID: 27119078; PMCID: PMC4826913.
    21. Sarker-Nag A, Hutcheon AE, Karamichos D. Mitochondrial Profile and Responses to TGF-ß Ligands in Keratoconus. Curr Eye Res. 2016 07; 41(7):900-7. PMID: 26430764.
      View in: PubMed
    22. McKay TB, Sarker-Nag A, Lyon D, Asara JM, Karamichos D. Quercetin modulates keratoconus metabolism in vitro. Cell Biochem Funct. 2015 Jul; 33(5):341-50. PMID: 26173740.
      View in: PubMed
    23. Lyon D', McKay TB, Sarkar-Nag A, Priyadarsini S, Karamichos D. Human Keratoconus Cell Contractility is Mediated by Transforming Growth Factor-Beta Isoforms. J Funct Biomater. 2015 Jun 18; 6(2):422-38. PMID: 26096146; PMCID: PMC4493522.
    24. Drevets P, Chucair-Elliott A, Shrestha P, Jinkins J, Karamichos D, Carr DJ. The use of human cornea organotypic cultures to study herpes simplex virus type 1 (HSV-1)-induced inflammation. Graefes Arch Clin Exp Ophthalmol. 2015 Oct; 253(10):1721-8. PMID: 26047535; PMCID: PMC4573349 [Available on 10/01/16].
    25. Priyadarsini S, McKay TB, Sarker-Nag A, Karamichos D. Keratoconus in vitro and the key players of the TGF-ß pathway. Mol Vis. 2015; 21:577-88. PMID: 26015770; PMCID: PMC4443584.
    26. Karamichos D. Ocular tissue engineering: current and future directions. J Funct Biomater. 2015 Feb 17; 6(1):77-80. PMID: 25695336; PMCID: PMC4384102.
    27. Karamichos D, Zieske JD, Sejersen H, Sarker-Nag A, Asara JM, Hjortdal J. Tear metabolite changes in keratoconus. Exp Eye Res. 2015 Mar; 132:1-8. PMID: 25579606; PMCID: PMC4436698.
    28. Priyadarsini S, Sarker-Nag A, Allegood J, Chalfant C, Karamichos D. Description of the sphingolipid content and subspecies in the diabetic cornea. Curr Eye Res. 2015; 40(12):1204-10. PMID: 25426847; PMCID: PMC4763931.
    29. Priyadarsini S, Hjortdal J, Sarker-Nag A, Sejersen H, Asara JM, Karamichos D. Gross cystic disease fluid protein-15/prolactin-inducible protein as a biomarker for keratoconus disease. PLoS One. 2014; 9(11):e113310. PMID: 25405607; PMCID: PMC4236164.
    30. Karamichos D, Hjortdal J. Keratoconus: tissue engineering and biomaterials. J Funct Biomater. 2014 Sep 11; 5(3):111-34. PMID: 25215423; PMCID: PMC4192608.
    31. Karamichos D, Hutcheon AE, Zieske JD. Reversal of fibrosis by TGF-ß3 in a 3D in vitro model. Exp Eye Res. 2014 Jul; 124:31-6. PMID: 24800655; PMCID: PMC4065812.
    32. Karamichos D, Funderburgh ML, Hutcheon AE, Zieske JD, Du Y, Wu J, Funderburgh JL. A role for topographic cues in the organization of collagenous matrix by corneal fibroblasts and stem cells. PLoS One. 2014; 9(1):e86260. PMID: 24465995; PMCID: PMC3897697.
    33. Karamichos D, Rich CB, Zareian R, Hutcheon AE, Ruberti JW, Trinkaus-Randall V, Zieske JD. TGF-ß3 stimulates stromal matrix assembly by human corneal keratocyte-like cells. Invest Ophthalmol Vis Sci. 2013 Oct 09; 54(10):6612-9. PMID: 24022012; PMCID: PMC3803138.
    34. Karamichos D, Zareian R, Guo X, Hutcheon AE, Ruberti JW, Zieske JD. Novel in Vitro Model for Keratoconus Disease. J Funct Biomater. 2012 Nov 13; 3(4):760-775. PMID: 23888249.
      View in: PubMed
    35. Karamichos D, Rich CB, Hutcheon AE, Ren R, Saitta B, Trinkaus-Randall V, Zieske JD. Self-assembled matrix by umbilical cord stem cells. J Funct Biomater. 2011 Sep 01; 2(3):213-29. PMID: 24956304; PMCID: PMC4030936.
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