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Last Name

Franklin A Hays

InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentBiochemistry/Molecular Biology
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    Collapse Biography 
    Collapse education and training
    Oregon State University, Corvallis, ORPhD2005Biochemistry and Biophysics
    University of California, San Francisco, CAPostDoc2009Membrane protein structure & function
    University of Oklahoma, Oklahoma City, OKPostDoc2010Glycobiology

    Collapse Research 
    Collapse research activities and funding
    R01GM118599     (HAYS, FRANKLIN ALAN)Sep 15, 2016 - Jul 31, 2020
    Deciphering ShcA-mediated ROS Production as a Novel Intervention Strategy in Diabetes Therapy
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Yan Q, Lin M, Huang W, Teymournejad O, Johnson JM, Hays FA, Liang Z, Li G, Rikihisa Y. Ehrlichia type IV secretion system effector Etf-2 binds to active RAB5 and delays endosome maturation. Proc Natl Acad Sci U S A. 2018 09 18; 115(38):E8977-E8986. PMID: 30181274.
      View in: PubMed
    2. Tsutsui Y, Hays FA. A Link Between Alzheimer's and Type II Diabetes Mellitus? Ca+2 -Mediated Signal Control and Protein Localization. Bioessays. 2018 06; 40(6):e1700219. PMID: 29694668.
      View in: PubMed
    3. Boswell-Casteel RC, Johnson JM, Hays FA. Functional Characterization of the Saccharomyces cerevisiae Equilibrative Nucleoside Transporter 1 (ScENT1). Molecules. 2018 Mar 22; 23(4). PMID: 29565807.
      View in: PubMed
    4. Boswell-Casteel RC, Johnson JM, Roe-Žurž Z, Duggan KD, Schmitz H, Hays FA. Expression and purification of human and Saccharomyces cerevisiae equilibrative nucleoside transporters. Protein Expr Purif. 2018 Feb; 142:68-74. PMID: 28918196.
      View in: PubMed
    5. Du M, Martin A, Hays F, Johnson J, Farjo RA, Farjo KM. Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4. Mol Vis. 2017; 23:185-197. PMID: 28400700.
      View in: PubMed
    6. Boswell-Casteel RC, Hays FA. Equilibrative nucleoside transporters-A review. Nucleosides Nucleotides Nucleic Acids. 2017 Jan 02; 36(1):7-30. PMID: 27759477.
      View in: PubMed
    7. Tsutsui Y, Deredge D, Wintrode PL, Hays FA. Imatinib binding to human c-Src is coupled to inter-domain allostery and suggests a novel kinase inhibition strategy. Sci Rep. 2016 08 02; 6:30832. PMID: 27480221.
      View in: PubMed
    8. Boswell-Casteel RC, Johnson JM, Stroud RM, Hays FA. Integral Membrane Protein Expression in Saccharomyces cerevisiae. Methods Mol Biol. 2016; 1432:163-86. PMID: 27485336.
      View in: PubMed
    9. Zhang Z, Subramaniam S, Kale J, Liao C, Huang B, Brahmbhatt H, Condon SG, Lapolla SM, Hays FA, Ding J, He F, Zhang XC, Li J, Senes A, Andrews DW, Lin J. BH3-in-groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes. EMBO J. 2016 Jan 18; 35(2):208-36. PMID: 26702098; PMCID: PMC4718459 [Available on 01/18/17].
    10. Tsutsui Y, Johnson JM, Demeler B, Kinter MT, Hays FA. Conformation-Dependent Human p52Shc Phosphorylation by Human c-Src. Biochemistry. 2015 Jun 09; 54(22):3469-82. PMID: 25961473.
      View in: PubMed
    11. Boswell-Casteel RC, Johnson JM, Duggan KD, Tsutsui Y, Hays FA. Overproduction and biophysical characterization of human HSP70 proteins. Protein Expr Purif. 2015 Feb; 106:57-65. PMID: 25266791; PMCID: PMC4248018.
    12. Boswell-Casteel RC, Johnson JM, Duggan KD, Roe-Žurž Z, Schmitz H, Burleson C, Hays FA. FUN26 (function unknown now 26) protein from saccharomyces cerevisiae is a broad selectivity, high affinity, nucleoside and nucleobase transporter. J Biol Chem. 2014 Aug 29; 289(35):24440-51. PMID: 25035431; PMCID: PMC4148870.
    13. Hays FA, Roe-Zurz Z, Stroud RM. Overexpression and purification of integral membrane proteins in yeast. Methods Enzymol. 2010; 470:695-707. PMID: 20946832.
      View in: PubMed
    14. Kelly L, Pieper U, Eswar N, Hays FA, Li M, Roe-Zurz Z, Kroetz DL, Giacomini KM, Stroud RM, Sali A. A survey of integral alpha-helical membrane proteins. J Struct Funct Genomics. 2009 Dec; 10(4):269-80. PMID: 19760129.
      View in: PubMed
    15. Newby ZE, O'Connell JD, Gruswitz F, Hays FA, Harries WE, Harwood IM, Ho JD, Lee JK, Savage DF, Miercke LJ, Stroud RM. A general protocol for the crystallization of membrane proteins for X-ray structural investigation. Nat Protoc. 2009; 4(5):619-37. PMID: 19360018; PMCID: PMC4075773.
    16. Li M, Hays FA, Roe-Zurz Z, Vuong L, Kelly L, Ho CM, Robbins RM, Pieper U, O'Connell JD, Miercke LJ, Giacomini KM, Sali A, Stroud RM. Selecting optimum eukaryotic integral membrane proteins for structure determination by rapid expression and solubilization screening. J Mol Biol. 2009 Jan 23; 385(3):820-30. PMID: 19061901; PMCID: PMC2659619.
    17. Hays FA, Roe-Zurz Z, Li M, Kelly L, Gruswitz F, Sali A, Stroud RM. Ratiocinative screen of eukaryotic integral membrane protein expression and solubilization for structure determination. J Struct Funct Genomics. 2009 Mar; 10(1):9-16. PMID: 19031011; PMCID: PMC2756966.
    18. Menuz K, Stroud RM, Nicoll RA, Hays FA. TARP auxiliary subunits switch AMPA receptor antagonists into partial agonists. Science. 2007 Nov 02; 318(5851):815-7. PMID: 17975069.
      View in: PubMed
    19. Voth AR, Hays FA, Ho PS. Directing macromolecular conformation through halogen bonds. Proc Natl Acad Sci U S A. 2007 Apr 10; 104(15):6188-93. PMID: 17379665.
      View in: PubMed
    20. Khuu PA, Voth AR, Hays FA, Ho PS. The stacked-X DNA Holliday junction and protein recognition. J Mol Recognit. 2006 May-Jun; 19(3):234-242. PMID: 16575941; PMCID: PMC4537160.
    21. Hays FA, Schirf V, Ho PS, Demeler B. Solution formation of Holliday junctions in inverted-repeat DNA sequences. Biochemistry. 2006 Feb 28; 45(8):2467-71. PMID: 16489738; PMCID: PMC2034439.
    22. Hays FA, Teegarden A, Jones ZJ, Harms M, Raup D, Watson J, Cavaliere E, Ho PS. How sequence defines structure: a crystallographic map of DNA structure and conformation. Proc Natl Acad Sci U S A. 2005 May 17; 102(20):7157-62. PMID: 15870206; PMCID: PMC1129101.
    23. Auffinger P, Hays FA, Westhof E, Ho PS. Halogen bonds in biological molecules. Proc Natl Acad Sci U S A. 2004 Nov 30; 101(48):16789-94. PMID: 15557000; PMCID: PMC529416.
    24. Hays FA, Jones ZJ, Ho PS. Influence of minor groove substituents on the structure of DNA Holliday junctions. Biochemistry. 2004 Aug 03; 43(30):9813-22. PMID: 15274635.
      View in: PubMed
    25. Watson J, Hays FA, Ho PS. Definitions and analysis of DNA Holliday junction geometry. Nucleic Acids Res. 2004; 32(10):3017-27. PMID: 15173384; PMCID: PMC434437.
    26. Hays FA, Watson J, Ho PS. Caution! DNA crossing: crystal structures of Holliday junctions. J Biol Chem. 2003 Dec 12; 278(50):49663-6. PMID: 14563836.
      View in: PubMed
    27. Hays FA, Vargason JM, Ho PS. Effect of sequence on the conformation of DNA holliday junctions. Biochemistry. 2003 Aug 19; 42(32):9586-97. PMID: 12911300.
      View in: PubMed
    28. Lehoux EA, Baker SM, Kovina MV, Hays FA, Spivey HO. Absence of evidence for metabolite-modulated association between alpha-glycerol-3-phosphate dehydrogenase and L-lactate dehydrogenase. Biochemistry. 2003 May 27; 42(20):6259-63. PMID: 12755630.
      View in: PubMed
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