Loading...
Header Logo
Keywords
Last Name
Institution

Hiroshi Yamada

TitleProf,Asst of Research
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentMedicine Hematology/Oncology
Phone405/271-8001
vCardDownload vCard

    Collapse Biography 
    Collapse education and training
    Kyoto University, Kyoto, JAPANMS1994Biophysics/Molecular Genetics
    Kyoto University, Kyoto, JAPANPhD1998Biophysics/Molecular Genetics
    AECOM, Bronx, NYPostdoc2000Cell Biology
    University of Oklahoma, Oklahoma CityPostdoc2003Cell Biology
    OMRF, Oklahoma City, OKAssociate2007Cell Biology

    Collapse Research 
    Collapse research activities and funding
    R03CA162538     (YAMADA, HIROSHI Y)Apr 1, 2012 - Mar 31, 2014
    NIH/NCI
    Understanding the role of Sgo1 in colorectal cancer
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Abe T, La TM, Miyagaki Y, Oya E, Wei FY, Sumida K, Fujise K, Takeda T, Tomizawa K, Takei K, Yamada H. Phosphorylation of cortactin by cyclin-dependent kinase 5 modulates actin bundling by the dynamin 1-cortactin ring-like complex and formation of filopodia and lamellipodia in NG108-15 glioma-derived cells. Int J Oncol. 2019 Feb; 54(2):550-558. PMID: 30570111.
      View in: PubMed
    2. Rao CV, Farooqui M, Asch AS, Yamada HY. Critical role of mitosis in spontaneous late-onset Alzheimer's disease; from a Shugoshin 1 cohesinopathy mouse model. Cell Cycle. 2018; 17(19-20):2321-2334. PMID: 30231670.
      View in: PubMed
    3. Rao CV, Farooqui M, Zhang Y, Asch AS, Yamada HY. Spontaneous development of Alzheimer's disease-associated brain pathology in a Shugoshin-1 mouse cohesinopathy model. Aging Cell. 2018 Jun 25; e12797. PMID: 29943428.
      View in: PubMed
    4. Rao CV, Pal S, Mohammed A, Farooqui M, Doescher MP, Asch AS, Yamada HY. Biological effects and epidemiological consequences of arsenic exposure, and reagents that can ameliorate arsenic damage in vivo. Oncotarget. 2017 Aug 22; 8(34):57605-57621. PMID: 28915699.
      View in: PubMed
    5. Rao CV, Asch AS, Yamada HY. Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer. Carcinogenesis. 2017 01; 38(1):2-11. PMID: 27838634.
      View in: PubMed
    6. Rao CV, Asch AS, Yamada HY. Emerging links among Chromosome Instability (CIN), cancer, and aging. Mol Carcinog. 2017 03; 56(3):791-803. PMID: 27533343.
      View in: PubMed
    7. Yamada H, Takeda T, Michiue H, Abe T, Takei K. Actin bundling by dynamin 2 and cortactin is implicated in cell migration by stabilizing filopodia in human non-small cell lung carcinoma cells. Int J Oncol. 2016 Sep; 49(3):877-86. PMID: 27572123; PMCID: PMC4948956.
    8. Rao CV, Sanghera S, Zhang Y, Biddick L, Reddy A, Lightfoot S, Janakiram NB, Mohammed A, Dai W, Yamada HY. Systemic Chromosome Instability Resulted in Colonic Transcriptomic Changes in Metabolic, Proliferation, and Stem Cell Regulators in Sgo1-/+ Mice. Cancer Res. 2016 Feb 01; 76(3):630-42. PMID: 26833665.
      View in: PubMed
    9. Mohammed A, Janakiram NB, Madka V, Brewer M, Ritchie RL, Lightfoot S, Kumar G, Sadeghi M, Patlolla JM, Yamada HY, Cruz-Monserrate Z, May R, Houchen CW, Steele VE, Rao CV. Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression. Oncotarget. 2015 Jun 20; 6(17):15524-39. PMID: 25906749; PMCID: PMC4558168.
    10. Rao CV, Sanghera S, Zhang Y, Biddick L, Reddy A, Lightfoot S, Dai W, Yamada HY. Antagonizing pathways leading to differential dynamics in colon carcinogenesis in Shugoshin1 (Sgo1)-haploinsufficient chromosome instability model. Mol Carcinog. 2016 May; 55(5):600-10. PMID: 25773652.
      View in: PubMed
    11. Yamada HY, Zhang Y, Reddy A, Mohammed A, Lightfoot S, Dai W, Rao CV. Tumor-promoting/progressing role of additional chromosome instability in hepatic carcinogenesis in Sgo1 (Shugoshin 1) haploinsufficient mice. Carcinogenesis. 2015 Apr; 36(4):429-40. PMID: 25740822; PMCID: PMC4392605.
    12. Omura K, Uehara T, Morikawa Y, Hayashi H, Mitsumori K, Minami K, Kanki M, Yamada H, Ono A, Urushidani T. Detection of initiating potential of non-genotoxic carcinogens in a two-stage hepatocarcinogenesis study in rats. J Toxicol Sci. 2014; 39(5):785-94. PMID: 25242409.
      View in: PubMed
    13. Omura K, Uehara T, Morikawa Y, Hayashi H, Mitsumori K, Minami K, Kanki M, Yamada H, Ono A, Urushidani T. Comprehensive analysis of DNA methylation and gene expression of rat liver in a 2-stage hepatocarcinogenesis model. J Toxicol Sci. 2014; 39(6):837-48. PMID: 25374375.
      View in: PubMed
    14. Rao CV, Yamada HY. Genomic instability and colon carcinogenesis: from the perspective of genes. Front Oncol. 2013; 3:130. PMID: 23734346; PMCID: PMC3659308.
    15. Yamada H, Abe T, Satoh A, Okazaki N, Tago S, Kobayashi K, Yoshida Y, Oda Y, Watanabe M, Tomizawa K, Matsui H, Takei K. Stabilization of actin bundles by a dynamin 1/cortactin ring complex is necessary for growth cone filopodia. J Neurosci. 2013 Mar 06; 33(10):4514-26. PMID: 23467367.
      View in: PubMed
    16. Rao CV, Kurkjian CD, Yamada HY. Mitosis-targeting natural products for cancer prevention and therapy. Curr Drug Targets. 2012 Dec; 13(14):1820-30. PMID: 23140292.
      View in: PubMed
    17. Hirata T, Watanabe M, Kaku H, Kobayashi Y, Yamada H, Sakaguchi M, Takei K, Huh NH, Nasu Y, Kumon H. REIC/Dkk-3-encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer. Int J Oncol. 2012 Aug; 41(2):559-64. PMID: 22665039.
      View in: PubMed
    18. Ueki H, Watanabe M, Kaku H, Huang P, Li SA, Ochiai K, Hirata T, Noguchi H, Yamada H, Takei K, Nasu Y, Kashiwakura Y, Kumon H. A novel gene expression system for detecting viable bladder cancer cells. Int J Oncol. 2012 Jul; 41(1):135-40. PMID: 22470055.
      View in: PubMed
    19. Yamada HY, Yao Y, Wang X, Zhang Y, Huang Y, Dai W, Rao CV. Haploinsufficiency of SGO1 results in deregulated centrosome dynamics, enhanced chromosomal instability and colon tumorigenesis. Cell Cycle. 2012 Feb 01; 11(3):479-88. PMID: 22262168; PMCID: PMC3315092.
    20. Uehara T, Minowa Y, Morikawa Y, Kondo C, Maruyama T, Kato I, Nakatsu N, Igarashi Y, Ono A, Hayashi H, Mitsumori K, Yamada H, Ohno Y, Urushidani T. Prediction model of potential hepatocarcinogenicity of rat hepatocarcinogens using a large-scale toxicogenomics database. Toxicol Appl Pharmacol. 2011 Sep 15; 255(3):297-306. PMID: 21784091.
      View in: PubMed
    21. Zhang K, Watanabe M, Kashiwakura Y, Li SA, Edamura K, Huang P, Yamaguchi K, Nasu Y, Kobayashi Y, Sakaguchi M, Ochiai K, Yamada H, Takei K, Ueki H, Huh NH, Li M, Kaku H, Na Y, Kumon H. Expression pattern of REIC/Dkk-3 in various cell types and the implications of the soluble form in prostatic acinar development. Int J Oncol. 2010 Dec; 37(6):1495-501. PMID: 21042718.
      View in: PubMed
    22. Yamada HY, Rao CV. Genes that modulate the sensitivity for anti-microtubule drug-mediated chemotherapy. Curr Cancer Drug Targets. 2010 Sep; 10(6):623-33. PMID: 20491618.
      View in: PubMed
    23. Yamada HY, Rao CV. BRD8 is a potential chemosensitizing target for spindle poisons in colorectal cancer therapy. Int J Oncol. 2009 Nov; 35(5):1101-9. PMID: 19787264.
      View in: PubMed
    24. Rao CV, Yamada HY, Yao Y, Dai W. Enhanced genomic instabilities caused by deregulated microtubule dynamics and chromosome segregation: a perspective from genetic studies in mice. Carcinogenesis. 2009 Sep; 30(9):1469-74. PMID: 19372138; PMCID: PMC2736299.
    25. Yamada HY, Gorbsky GJ. Spindle checkpoint function and cellular sensitivity to antimitotic drugs. Mol Cancer Ther. 2006 Dec; 5(12):2963-9. PMID: 17172401; PMCID: PMC2596631.
    26. Yamada HY, Gorbsky GJ. Cell-based expression cloning for identification of polypeptides that hypersensitize mammalian cells to mitotic arrest. Biol Proced Online. 2006; 8:36-43. PMID: 16799695; PMCID: PMC1455480.
    27. Yamada HY, Gorbsky GJ. Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons. Mol Cancer Ther. 2006 Jan; 5(1):29-38. PMID: 16432160; PMCID: PMC1630635.
    28. Klinman DM, Zeuner R, Yamada H, Gursel M, Currie D, Gursel I. Regulation of CpG-induced immune activation by suppressive oligodeoxynucleotides. Ann N Y Acad Sci. 2003 Dec; 1002:112-23. PMID: 14751829.
      View in: PubMed
    29. Gursel I, Gursel M, Yamada H, Ishii KJ, Takeshita F, Klinman DM. Repetitive elements in mammalian telomeres suppress bacterial DNA-induced immune activation. J Immunol. 2003 Aug 01; 171(3):1393-400. PMID: 12874230.
      View in: PubMed
    30. Yamada H, Gursel I, Takeshita F, Conover J, Ishii KJ, Gursel M, Takeshita S, Klinman DM. Effect of suppressive DNA on CpG-induced immune activation. J Immunol. 2002 Nov 15; 169(10):5590-4. PMID: 12421936.
      View in: PubMed
    Yamada's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description