Loading...
Header Logo
Keywords
Last Name
Institution

Jay S Hanas

TitleProfessor
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentBiochemistry/Molecular Biology
Address940 Stanton L Young Blvd
Oklahoma City OK 73104-5020
Phone405/271-2227
vCardDownload vCard

    Collapse Research 
    Collapse research activities and funding
    R29GM040670     (HANAS, JAY S.)Jul 1, 1988 - Jun 30, 1995
    NIH/NIGMS
    TRANSCRIPTION FACTOR IIIA STRUCTURE, FUNCTION, EVOLUTION
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Qu D, Johnson J, Chandrakesan P, Weygant N, May R, Aiello N, Rhim A, Zhao L, Zheng W, Lightfoot S, Pant S, Irvan J, Postier R, Hocker J, Hanas JS, Ali N, Sureban SM, An G, Schlosser MJ, Stanger B, Houchen CW. Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells. PLoS One. 2015; 10(2):e0118933. PMID: 25723399; PMCID: PMC4344195.
    2. Hocker JR, Postier RG, Li M, Lerner MR, Lightfoot SA, Peyton MD, Deb SJ, Baker CM, Williams TL, Hanas RJ, Stowell DE, Lander TJ, Brackett DJ, Hanas JS. Discriminating patients with early-stage pancreatic cancer or chronic pancreatitis using serum electrospray mass profiling. Cancer Lett. 2015 Apr 10; 359(2):314-24. PMID: 25637792; PMCID: PMC4347843.
    3. Hanas JS, Peyton MD, Lerner MR, Lightfoot SA, Deb SJ, Hanas RJ, Vu NT, Kupiec TC, Stowell DE, Brackett DJ, Dubinett SM, Hocker JR. Distinguishing patients with stage I lung cancer versus control individuals using serum mass profiling. Cancer Invest. 2014 May; 32(4):136-43. PMID: 24579933.
      View in: PubMed
    4. Hocker JR, Mohammed A, Aston CE, Brewer M, Lightfoot SA, Rao CV, Hanas JS. Mass profiling of serum to distinguish mice with pancreatic cancer induced by a transgenic Kras mutation. Int J Cancer. 2013 Dec 01; 133(11):2662-71. PMID: 23712558; PMCID: PMC3787968.
    5. Hocker JR, Drevets DA, Dillon MJ, Hanas JS. Discriminating experimental Listeria monocytogenes infections in mice using serum profiling. Appl Microbiol Biotechnol. 2012 Nov; 96(4):1049-58. PMID: 23053068.
      View in: PubMed
    6. Hocker JR, Bishop EA, Lightfoot SA, Lerner MR, Peyton MD, Brackett DJ, Hanas RJ, McMeekin DS, Walker JL, Hanas JS. Serum profiling to distinguish early- and late-stage ovarian cancer patients from disease-free individuals. Cancer Invest. 2012 Feb; 30(2):189-97. PMID: 22149058.
      View in: PubMed
    7. Hocker JR, Peyton MD, Lerner MR, Lightfoot SA, Hanas RJ, Brackett DJ, Hanas JS. Distinguishing non-small cell lung adenocarcinoma patients from squamous cell carcinoma patients and control individuals using serum profiling. Cancer Invest. 2012 Feb; 30(2):180-8. PMID: 22149138.
      View in: PubMed
    8. Hocker JR, Peyton MD, Lerner MR, Mitchell SL, Lightfoot SA, Lander TJ, Bates-Albers LM, Vu NT, Hanas RJ, Kupiec TC, Brackett DJ, Hanas JS. Serum discrimination of early-stage lung cancer patients using electrospray-ionization mass spectrometry. Lung Cancer. 2011 Nov; 74(2):206-11. PMID: 21529985.
      View in: PubMed
    9. Hocker JR, Lerner MR, Mitchell SL, Lightfoot SA, Lander TJ, Quillet AA, Hanas RJ, Peyton MD, Postier RG, Brackett DJ, Hanas JS. Distinguishing early-stage pancreatic cancer patients from disease-free individuals using serum profiling. Cancer Invest. 2011 Feb; 29(2):173-9. PMID: 21261478.
      View in: PubMed
    10. Hanas JS, Bruce Briggs G, Lerner MR, Lightfoot SA, Larabee JL, Karsies TJ, Epstein RB, Hanas RJ, Brackett DJ, Hocker JR. Systemic molecular and cellular changes induced in rats upon inhalation of JP-8 petroleum fuel vapor. Toxicol Mech Methods. 2010 May; 20(4):204-12. PMID: 20233090.
      View in: PubMed
    11. Larabee JL, Hocker JR, Hanas JS. Mechanisms of inhibition of zinc-finger transcription factors by selenium compounds ebselen and selenite. J Inorg Biochem. 2009 Mar; 103(3):419-26. PMID: 19167089.
      View in: PubMed
    12. Larabee JL, Hocker JR, Cheung JY, Gallucci RM, Hanas JS. Serum Profiling of Rat Dermal Exposure to JP-8 Fuel Reveals an Acute-Phase Response. Toxicol Mech Methods. 2008; 18(1):41-51. PMID: 20020890.
      View in: PubMed
    13. Hanas JS, Hocker JR, Cheung JY, Larabee JL, Lerner MR, Lightfoot SA, Morgan DL, Denson KD, Prejeant KC, Gusev Y, Smith BJ, Hanas RJ, Postier RG, Brackett DJ. Biomarker identification in human pancreatic cancer sera. Pancreas. 2008 Jan; 36(1):61-9. PMID: 18192883.
      View in: PubMed
    14. Smith BJ, Lightfoot SA, Lerner MR, Denson KD, Morgan DL, Hanas JS, Bronze MS, Postier RG, Brackett DJ. Induction of cardiovascular pathology in a novel model of low-grade chronic inflammation. Cardiovasc Pathol. 2009 Jan-Feb; 18(1):1-10. PMID: 18402801.
      View in: PubMed
    15. Larabee JL, Hocker JR, Hanas JS. Mechanisms of aurothiomalate-Cys2His2 zinc finger interactions. Chem Res Toxicol. 2005 Dec; 18(12):1943-54. PMID: 16359185.
      View in: PubMed
    16. Smith BJ, Lerner MR, Bu SY, Lucas EA, Hanas JS, Lightfoot SA, Postier RG, Bronze MS, Brackett DJ. Systemic bone loss and induction of coronary vessel disease in a rat model of chronic inflammation. Bone. 2006 Mar; 38(3):378-86. PMID: 16256450.
      View in: PubMed
    17. Larabee JL, Hocker JR, Lerner MR, Lightfoot SA, Cheung JY, Brackett DJ, Gallucci RM, Hanas JS. Stress induced in heart and other tissues by rat dermal exposure to JP-8 fuel. Cell Biol Toxicol. 2005 Sep-Nov; 21(5-6):233-46. PMID: 16323059.
      View in: PubMed
    18. Larabee JL, Hocker JR, Hanas JS. Cys redox reactions and metal binding of a Cys2His2 zinc finger. Arch Biochem Biophys. 2005 Feb 01; 434(1):139-49. PMID: 15629117.
      View in: PubMed
    19. Gonzalez ML, Frank MB, Ramsland PA, Hanas JS, Waxman FJ. Structural analysis of IgG2A monoclonal antibodies in relation to complement deposition and renal immune complex deposition. Mol Immunol. 2003 Oct; 40(6):307-17. PMID: 14522012.
      View in: PubMed
    20. Brackett DJ, Smith BJ, Lerner MR, Hanas JS, Postier RG. Gene activity associated with cancers treated by surgical oncologists. J Okla State Med Assoc. 2003 Oct; 96(10):485-94. PMID: 14619604.
      View in: PubMed
    21. Carr ML, Lerner MR, Hanas JS, Pennington LR, Brackett DJ, Epstein RB. A rat model of syngeneic bone marrow transplantation during breast cancer therapy. Bone Marrow Transplant. 2003 Jun; 31(11):1037-41. PMID: 12774057.
      View in: PubMed
    22. Postier RG, Lerner MR, Lightfoot SA, Vannarath R, Lane MM, Hanas JS, Brackett DJ. DNA ploidy and markovian analysis of neoplastic progression in experimental pancreatic cancer. J Histochem Cytochem. 2003 Mar; 51(3):303-9. PMID: 12588958.
      View in: PubMed
    23. Larabee JL, Hocker JR, Hanas RJ, Kahn FM, Hanas JS. Inhibition of zinc finger protein-DNA interactions by sodium selenite. Biochem Pharmacol. 2002 Dec 15; 64(12):1757-65. PMID: 12445865.
      View in: PubMed
    24. Trachte AL, Suthers SE, Lerner MR, Hanas JS, Jupe ER, Sienko AE, Adesina AM, Lightfoot SA, Brackett DJ, Postier RG. Increased expression of alpha-1-antitrypsin, glutathione S-transferase pi and vascular endothelial growth factor in human pancreatic adenocarcinoma. Am J Surg. 2002 Dec; 184(6):642-7; discussion 647-8. PMID: 12488200.
      View in: PubMed
    25. Hanas JS, Hocker JR, Cheng YG, Lerner MR, Brackett DJ, Lightfoot SA, Hanas RJ, Madhusudhan KT, Moreland RJ. cDNA cloning, DNA binding, and evolution of mammalian transcription factor IIIA. Gene. 2002 Jan 09; 282(1-2):43-52. PMID: 11814676.
      View in: PubMed
    26. Rodgers JS, Hocker JR, Hanas RJ, Nwosu EC, Hanas JS. Mercuric ion inhibition of eukaryotic transcription factor binding to DNA. Biochem Pharmacol. 2001 Jun 15; 61(12):1543-50. PMID: 11377384.
      View in: PubMed
    27. Moreland RJ, Dresser ME, Rodgers JS, Roe BA, Conaway JW, Conaway RC, Hanas JS. Identification of a transcription factor IIIA-interacting protein. Nucleic Acids Res. 2000 May 01; 28(9):1986-93. PMID: 10756201; PMCID: PMC103300.
    28. Hanas JS, Rodgers JS, Bantle JA, Cheng YG. Lead inhibition of DNA-binding mechanism of Cys(2)His(2) zinc finger proteins. Mol Pharmacol. 1999 Nov; 56(5):982-8. PMID: 10531404.
      View in: PubMed
    29. Jett EA, Lerner MR, Lightfoot SA, Hanas JS, Brackett DJ, Hollingsworth AB. Prevention of rat mammary carcinoma utilizing leuprolide as an equivalent to oophorectomy. Breast Cancer Res Treat. 1999 Nov; 58(2):131-6. PMID: 10674877.
      View in: PubMed
    30. Hanas JS, Lerner MR, Lightfoot SA, Raczkowski C, Kastens DJ, Brackett DJ, Postier RG. Expression of the cyclin-dependent kinase inhibitor p21(WAF1/CIP1) and p53 tumor suppressor in dysplastic progression and adenocarcinoma in Barrett esophagus. Cancer. 1999 Sep 01; 86(5):756-63. PMID: 10463972.
      View in: PubMed
    31. Moreland RJ, Hanas JS, Conaway JW, Conaway RC. Mechanism of action of RNA polymerase II elongation factor Elongin. Maximal stimulation of elongation requires conversion of the early elongation complex to an Elongin-activable form. J Biol Chem. 1998 Oct 09; 273(41):26610-7. PMID: 9756900.
      View in: PubMed
    32. Hanas JS, Koelsch G, Moreland R, Wickham JQ. Differential requirements for basic amino acids in transcription factor IIIA-5S gene interaction. Biochim Biophys Acta. 1998 Jul 09; 1398(3):256-64. PMID: 9655916.
      View in: PubMed
    33. Hollingsworth AB, Lerner MR, Lightfoot SA, Wilkerson KB, Hanas JS, McCay PB, Brackett DJ. Prevention of DMBA-induced rat mammary carcinomas comparing leuprolide, oophorectomy, and tamoxifen. Breast Cancer Res Treat. 1998 Jan; 47(1):63-70. PMID: 9493977.
      View in: PubMed
    34. Ogilvie MK, Hanas JS. Molecular biology of vertebrate transcription factor IIIA: cloning and characterization of TFIIIA from channel catfish oocytes. Gene. 1997 Dec 12; 203(2):103-12. PMID: 9426240.
      View in: PubMed
    35. Farris AD, Gross JK, Hanas JS, Harley JB. Genes for murine Y1 and Y3 Ro RNAs have class 3 RNA polymerase III promoter structures and are unlinked on mouse chromosome 6. Gene. 1996 Sep 26; 174(1):35-42. PMID: 8863726.
      View in: PubMed
    36. Hanas JS, Gunn CG. Inhibition of transcription factor IIIA-DNA interactions by xenobiotic metal ions. Nucleic Acids Res. 1996 Mar 01; 24(5):924-30. PMID: 8600461; PMCID: PMC145705.
    37. Ogilvie MK, Smith JF, Hanas JS. Sequence divergence of a TFIIIA-type zinc finger protein from fish ovarian tissue. Nucleic Acids Res. 1993 Aug 25; 21(17):4152. PMID: 8371993; PMCID: PMC310031.
    38. Gaskins CJ, Smith JF, Ogilvie MK, Hanas JS. Comparison of the sequence and structure of transcription factor IIIA from Bufo americanus and Rana pipiens. Gene. 1992 Oct 21; 120(2):197-206. PMID: 1398134.
      View in: PubMed
    39. Hanas JS, Gaskins CJ, Smith JF, Ogilvie MK. Structure, function, evolution of transcription factor IIIA. Prog Nucleic Acid Res Mol Biol. 1992; 43:205-39. PMID: 1410446.
      View in: PubMed
    40. Smith JF, Hawkins J, Leonard RE, Hanas JS. Structural elements in the N-terminal half of transcription factor IIIA required for factor binding to the 5S RNA gene internal control region. Nucleic Acids Res. 1991 Dec 25; 19(24):6871-6. PMID: 1762917; PMCID: PMC329322.
    41. Hanas JS, Smith JF. Identification of a TFIIIA binding site on the 5' flanking region of the TFIIIA gene. Nucleic Acids Res. 1990 May 25; 18(10):2923-8. PMID: 2349091; PMCID: PMC330820.
    42. Gaskins CJ, Hanas JS. Sequence variation in transcription factor IIIA. Nucleic Acids Res. 1990 Apr 25; 18(8):2117-23. PMID: 2110661; PMCID: PMC330691.
    43. Hanas JS, Littell RM, Gaskins CJ, Zebrowski R. Zinc finger structure of a ribosomal gene-specific transcription factor. SAAS Bull Biochem Biotechnol. 1990 Jan; 3:85-90. PMID: 1367425.
      View in: PubMed
    44. Hanas JS, Littell RM, Gaskins CJ, Zebrowski R. Internal deletion mutants of Xenopus transcription factor IIIA. Nucleic Acids Res. 1989 Dec 11; 17(23):9861-70. PMID: 2690011; PMCID: PMC335219.
    45. Hanas JS, Duke AL, Gaskins CJ. Conformation states of Xenopus transcription factor IIIA. Biochemistry. 1989 May 02; 28(9):4083-8. PMID: 2502179.
      View in: PubMed
    46. Gaskins CJ, Fiser-Littell RM, Duke AL, Hanas JS. Species variation in transcription factor IIIA. Nucleic Acids Res. 1989 Jan 25; 17(2):781-94. PMID: 2783776; PMCID: PMC331619.
    47. Fiser-Littell RM, Hanas JS. Xenopus transcription factor IIIA-dependent DNA renaturation. J Biol Chem. 1988 Nov 15; 263(32):17136-41. PMID: 2460459.
      View in: PubMed
    48. Fiser-Littell RM, Duke AL, Yanchick JS, Hanas JS. Deletion of the N-terminal region of Xenopus transcription factor IIIA inhibits specific binding to the 5 S RNA gene. J Biol Chem. 1988 Feb 05; 263(4):1607-10. PMID: 2448298.
      View in: PubMed
    49. Fiser-Littell RM, Hanas JS. Novobiocin inhibits Xenopus transcription factor IIIA-DNA interactions. J Biol Chem. 1987 Sep 05; 262(25):11916-9. PMID: 2442153.
      View in: PubMed
    50. Hanas JS, Hazuda DJ, Wu CW. Xenopus transcription factor A promotes DNA reassociation. J Biol Chem. 1985 Oct 25; 260(24):13316-20. PMID: 2414278.
      View in: PubMed
    51. Hanas JS, Bogenhagen DF, Wu CW. Binding of Xenopus transcription factor A to 5S RNA and to single stranded DNA. Nucleic Acids Res. 1984 Mar 26; 12(6):2745-58. PMID: 6369252; PMCID: PMC318703.
    Hanas's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _