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Jialing Lin

TitleProf,Asoc
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentBiochemistry/Molecular Biology
Address940 Stanton L Young Blvd
Oklahoma City OK 73104-5020
Phone405/271-2227
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    Collapse Research 
    Collapse research activities and funding
    F32GM017828     (LIN, JIALING)Mar 14, 1996
    NIH/NIGMS
    MULTISPANNING PROTEIN INTEGRATION INTO THE ER ME
    Role: Principal Investigator

    R01GM062964     (LIN, JIALING)Apr 1, 2001 - Aug 31, 2015
    NIH/NIGMS
    Structure-Function of Bcl-2 Related Apoptosis Regulators in Membranes
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Niu X, Brahmbhatt H, Mergenthaler P, Zhang Z, Sang J, Daude M, Ehlert FGR, Diederich WE, Wong E, Zhu W, Pogmore J, Nandy JP, Satyanarayana M, Jimmidi RK, Arya P, Leber B, Lin J, Culmsee C, Yi J, Andrews DW. A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection. Cell Chem Biol. 2017 Apr 20; 24(4):493-506.e5. PMID: 28392146.
      View in: PubMed
    2. Liao C, Zhang Z, Kale J, Andrews DW, Lin J, Li J. Conformational Heterogeneity of Bax Helix 9 Dimer for Apoptotic Pore Formation. Sci Rep. 2016 Jul 06; 6:29502. PMID: 27381287; PMCID: PMC4933972.
    3. Zhang Z, Subramaniam S, Kale J, Liao C, Huang B, Brahmbhatt H, Condon SG, Lapolla SM, Hays FA, Ding J, He F, Zhang XC, Li J, Senes A, Andrews DW, Lin J. BH3-in-groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes. EMBO J. 2016 Jan 18; 35(2):208-36. PMID: 26702098; PMCID: PMC4718459 [Available on 01/18/17].
    4. Ding J, Mooers BH, Zhang Z, Kale J, Falcone D, McNichol J, Huang B, Zhang XC, Xing C, Andrews DW, Lin J. After embedding in membranes antiapoptotic Bcl-XL protein binds both Bcl-2 homology region 3 and helix 1 of proapoptotic Bax protein to inhibit apoptotic mitochondrial permeabilization. J Biol Chem. 2014 Apr 25; 289(17):11873-96. PMID: 24616095; PMCID: PMC4002096.
    5. Medina AP, Lin J, Weigel PH. Hyaluronan synthase mediates dye translocation across liposomal membranes. BMC Biochem. 2012 Jan 25; 13:2. PMID: 22276637; PMCID: PMC3331846.
    6. Ding J, Zhang Z, Roberts GJ, Falcone M, Miao Y, Shao Y, Zhang XC, Andrews DW, Lin J. Bcl-2 and Bax interact via the BH1-3 groove-BH3 motif interface and a novel interface involving the BH4 motif. J Biol Chem. 2010 Sep 10; 285(37):28749-63. PMID: 20584903; PMCID: PMC2937903.
    7. Peng J, Lapolla SM, Zhang Z, Lin J. The cytosolic domain of Bcl-2 forms small pores in model mitochondrial outer membrane after acidic pH-induced membrane association. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009 Feb; 26(1):130-7. PMID: 19334571; PMCID: PMC2844873.
    8. Lin J, Liang Z, Zhang Z, Li G. Membrane topography and topogenesis of prenylated Rab acceptor (PRA1). J Biol Chem. 2001 Nov 09; 276(45):41733-41. PMID: 11535589; PMCID: PMC1350924.
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