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Last Name
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John Kimble Frazer

TitleProf,Asst
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentDept of Pediatrics
Address941 Stanton L Young Blvd
Oklahoma City OK 73104-5019
Phone405/271-5311
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    Collapse Biography 
    Collapse education and training
    University of Texas, Dallas, TXPhD1998Molecular Microbiology

    Collapse Research 
    Collapse research activities and funding
    P20GM103636     (THOMPSON, LINDA F.)Mar 1, 2013 - Feb 28, 2018
    NIH
    Expanding Excellence in Developmental Biology in Oklahoma
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Squiban B, Ahmed ST, Frazer JK. Creation of a human T-ALL cell line online database. Leuk Lymphoma. 2017 11; 58(11):2728-2730. PMID: 28609209.
      View in: PubMed
    2. Miles RR, Shah RK, Frazer JK. Molecular genetics of childhood, adolescent and young adult non-Hodgkin lymphoma. Br J Haematol. 2016 05; 173(4):582-96. PMID: 26969846.
      View in: PubMed
    3. Shiramizu B, Goldman S, Smith L, Agsalda-Garcia M, Galardy P, Perkins SL, Frazer JK, Sanger W, Anderson JR, Gross TG, Weinstein H, Harrison L, Barth MJ, Mussolin L, Cairo MS. Impact of persistent minimal residual disease post-consolidation therapy in children and adolescents with advanced Burkitt leukaemia: a Children's Oncology Group Pilot Study Report. Br J Haematol. 2015 Aug; 170(3):367-71. PMID: 25858645; PMCID: PMC4503484.
    4. Goldman S, Smith L, Galardy P, Perkins SL, Frazer JK, Sanger W, Anderson JR, Gross TG, Weinstein H, Harrison L, Shiramizu B, Barth M, Cairo MS. Rituximab with chemotherapy in children and adolescents with central nervous system and/or bone marrow-positive Burkitt lymphoma/leukaemia: a Children's Oncology Group Report. Br J Haematol. 2014 Nov; 167(3):394-401. PMID: 25066629.
      View in: PubMed
    5. Squiban B, Frazer JK. Danio rerio: Small Fish Making a Big Splash in Leukemia. Curr Pathobiol Rep. 2014 Jun; 2(2):61-73. PMID: 26269780.
      View in: PubMed
    6. West K, Miles R, Kent ML, Frazer JK. Unusual fluorescent granulomas and myonecrosis in Danio rerio infected by the microsporidian pathogen Pseudoloma neurophilia. Zebrafish. 2014 Jun; 11(3):283-90. PMID: 24707848; PMCID: PMC4050717.
    7. Christoph S, Deryckere D, Schlegel J, Frazer JK, Batchelor LA, Trakhimets AY, Sather S, Hunter DM, Cummings CT, Liu J, Yang C, Kireev D, Simpson C, Norris-Drouin J, Hull-Ryde EA, Janzen WP, Johnson GL, Wang X, Frye SV, Earp HS, Graham DK. UNC569, a novel small-molecule mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo. Mol Cancer Ther. 2013 Nov; 12(11):2367-77. PMID: 23997116; PMCID: PMC3823742.
    8. Mangum DS, Downie J, Mason CC, Jahromi MS, Joshi D, Rodic V, Müschen M, Meeker N, Trede N, Frazer JK, Zhou Y, Cheng C, Jeha S, Pui CH, Willman CL, Harvey RC, Hunger SP, Yang JJ, Barnette P, Mullighan CG, Miles RR, Schiffman JD. VPREB1 deletions occur independent of lambda light chain rearrangement in childhood acute lymphoblastic leukemia. Leukemia. 2014 Jan; 28(1):216-20. PMID: 23881307; PMCID: PMC4043450.
    9. Frazer JK, Batchelor LA, Bradley DF, Brown KH, Dobrinski KP, Lee C, Trede NS. Genomic amplification of an endogenous retrovirus in zebrafish T-cell malignancies. Adv Hematol. 2012; 2012:627920. PMID: 22745640; PMCID: PMC3382231.
    10. El-Mallawany NK, Frazer JK, Van Vlierberghe P, Ferrando AA, Perkins S, Lim M, Chu Y, Cairo MS. Pediatric T- and NK-cell lymphomas: new biologic insights and treatment strategies. Blood Cancer J. 2012 Apr; 2(4):e65. PMID: 22829967; PMCID: PMC3346681.
    11. Ridges S, Heaton WL, Joshi D, Choi H, Eiring A, Batchelor L, Choudhry P, Manos EJ, Sofla H, Sanati A, Welborn S, Agarwal A, Spangrude GJ, Miles RR, Cox JE, Frazer JK, Deininger M, Balan K, Sigman M, Müschen M, Perova T, Johnson R, Montpellier B, Guidos CJ, Jones DA, Trede NS. Zebrafish screen identifies novel compound with selective toxicity against leukemia. Blood. 2012 Jun 14; 119(24):5621-31. PMID: 22490804; PMCID: PMC3382926.
    12. Rudner LA, Brown KH, Dobrinski KP, Bradley DF, Garcia MI, Smith AC, Downie JM, Meeker ND, Look AT, Downing JR, Gutierrez A, Mullighan CG, Schiffman JD, Lee C, Trede NS, Frazer JK. Shared acquired genomic changes in zebrafish and human T-ALL. Oncogene. 2011 Oct 13; 30(41):4289-96. PMID: 21552289; PMCID: PMC4811672.
    13. Meeker ND, Cherry AM, Bangs CD, Frazer JK. A pediatric B lineage leukemia with coincident MYC and MLL translocations. J Pediatr Hematol Oncol. 2011 Mar; 33(2):158-60. PMID: 20829716.
      View in: PubMed
    14. Meeker ND, Smith AC, Frazer JK, Bradley DF, Rudner LA, Love C, Trede NS. Characterization of the zebrafish T cell receptor beta locus. Immunogenetics. 2010 Jan; 62(1):23-9. PMID: 20054533.
      View in: PubMed
    15. Frazer JK, Meeker ND, Rudner L, Bradley DF, Smith AC, Demarest B, Joshi D, Locke EE, Hutchinson SA, Tripp S, Perkins SL, Trede NS. Heritable T-cell malignancy models established in a zebrafish phenotypic screen. Leukemia. 2009 Oct; 23(10):1825-35. PMID: 19516274; PMCID: PMC2761994.
    16. South ST, Frazer JK, Brothman AR, Chen Z. Unexpected cytogenetic finding in acute lymphoblastic leukemia: a case of del(5q) with a cryptic t(12;21). Cancer Genet Cytogenet. 2006 Jul 15; 168(2):177-8. PMID: 16843112.
      View in: PubMed
    17. Bonkowsky JL, Frazer JK, Buchi KF, Byington CL. Metamizole use by Latino immigrants: a common and potentially harmful home remedy. Pediatrics. 2002 Jun; 109(6):e98. PMID: 12042592.
      View in: PubMed
    18. Frazer JK, Jackson DG, Gaillard JP, Lutter M, Liu YJ, Banchereau J, Capra JD, Pascual V. Identification of centerin: a novel human germinal center B cell-restricted serpin. Eur J Immunol. 2000 Oct; 30(10):3039-48. PMID: 11069088.
      View in: PubMed
    19. Yun TJ, Chaudhary PM, Shu GL, Frazer JK, Ewings MK, Schwartz SM, Pascual V, Hood LE, Clark EA. OPG/FDCR-1, a TNF receptor family member, is expressed in lymphoid cells and is up-regulated by ligating CD40. J Immunol. 1998 Dec 01; 161(11):6113-21. PMID: 9834095.
      View in: PubMed
    20. Frazer JK, Pascual V, Capra JD. RDA of lymphocyte subsets. J Immunol Methods. 1997 Aug 22; 207(1):1-12. PMID: 9328581.
      View in: PubMed
    21. Frazer JK, LeGros J, de Bouteiller O, Liu YJ, Banchereau J, Pascual V, Capra JD. Identification and cloning of genes expressed by human tonsillar B lymphocyte subsets. Ann N Y Acad Sci. 1997 Apr 05; 815:316-8. PMID: 9186668.
      View in: PubMed
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