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Julio C. Morales

TitleProf,Asst
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentNeurosurgery
Phone405/271-2216
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    Collapse Biography 
    Collapse education and training
    University of Texas, Houston, TXPhD2006Biochemistry

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Quintana EM, Valdes PV, Deza EM, García AG, Rodríguez MC, Pérez JMJ, Chaviano J, Morales JCG, Batista KP, García FA. Initial experience and one-year follow-up with Neuroform Atlas Stent System for the treatment of brain aneurysms. Interv Neuroradiol. 2019 Apr 02; 1591019918819087. PMID: 30939955.
      View in: PubMed
    2. Motea EA, Fattah FJ, Xiao L, Girard L, Rommel A, Morales JC, Patidar P, Zhou Y, Porter A, Xie Y, Minna JD, Boothman DA. Kub5-Hera RPRD1B Deficiency Promotes "BRCAness" and Vulnerability to PARP Inhibition in BRCA-proficient Breast Cancers. Clin Cancer Res. 2018 Dec 15; 24(24):6459-6470. PMID: 30108102.
      View in: PubMed
    3. Morales JC, Richard P, Patidar PL, Motea EA, Dang TT, Manley JL, Boothman DA. XRN2 Links Transcription Termination to DNA Damage and Replication Stress. PLoS Genet. 2016 07; 12(7):e1006107. PMID: 27437695.
      View in: PubMed
    4. Tang KJ, Constanzo JD, Venkateswaran N, Melegari M, Ilcheva M, Morales JC, Skoulidis F, Heymach JV, Boothman DA, Scaglioni PP. Focal Adhesion Kinase Regulates the DNA Damage Response and Its Inhibition Radiosensitizes Mutant KRAS Lung Cancer. Clin Cancer Res. 2016 Dec 01; 22(23):5851-5863. PMID: 27220963.
      View in: PubMed
    5. Patidar PL, Motea EA, Fattah FJ, Zhou Y, Morales JC, Xie Y, Garner HR, Boothman DA. The Kub5-Hera/RPRD1B interactome: a novel role in preserving genetic stability by regulating DNA mismatch repair. Nucleic Acids Res. 2016 Feb 29; 44(4):1718-31. PMID: 26819409.
      View in: PubMed
    6. Cao L, Li LS, Spruell C, Xiao L, Chakrabarti G, Bey EA, Reinicke KE, Srougi MC, Moore Z, Dong Y, Vo P, Kabbani W, Yang CR, Wang X, Fattah F, Morales JC, Motea EA, Bornmann WG, Yordy JS, Boothman DA. Tumor-selective, futile redox cycle-induced bystander effects elicited by NQO1 bioactivatable radiosensitizing drugs in triple-negative breast cancers. Antioxid Redox Signal. 2014 Jul 10; 21(2):237-50. PMID: 24512128.
      View in: PubMed
    7. Morales JC, Richard P, Rommel A, Fattah FJ, Motea EA, Patidar PL, Xiao L, Leskov K, Wu SY, Hittelman WN, Chiang CM, Manley JL, Boothman DA. Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair. Nucleic Acids Res. 2014 Apr; 42(8):4996-5006. PMID: 24589584.
      View in: PubMed
    8. Morales J, Li L, Fattah FJ, Dong Y, Bey EA, Patel M, Gao J, Boothman DA. Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases. Crit Rev Eukaryot Gene Expr. 2014; 24(1):15-28. PMID: 24579667.
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    9. Li LS, Morales JC, Veigl M, Sedwick D, Greer S, Meyers M, Wagner M, Fishel R, Boothman DA. DNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets. Br J Pharmacol. 2009 Oct; 158(3):679-92. PMID: 19775280.
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    10. Wagner MW, Li LS, Morales JC, Galindo CL, Garner HR, Bornmann WG, Boothman DA. Role of c-Abl kinase in DNA mismatch repair-dependent G2 cell cycle checkpoint arrest responses. J Biol Chem. 2008 Aug 01; 283(31):21382-93. PMID: 18480061.
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    11. Li LS, Morales JC, Hwang A, Wagner MW, Boothman DA. DNA mismatch repair-dependent activation of c-Abl/p73alpha/GADD45alpha-mediated apoptosis. J Biol Chem. 2008 Aug 01; 283(31):21394-403. PMID: 18480060.
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    12. Morales JC, Franco S, Murphy MM, Bassing CH, Mills KD, Adams MM, Walsh NC, Manis JP, Rassidakis GZ, Alt FW, Carpenter PB. 53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3310-5. PMID: 16492765.
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    13. Franco S, Gostissa M, Zha S, Lombard DB, Murphy MM, Zarrin AA, Yan C, Tepsuporn S, Morales JC, Adams MM, Lou Z, Bassing CH, Manis JP, Chen J, Carpenter PB, Alt FW. H2AX prevents DNA breaks from progressing to chromosome breaks and translocations. Mol Cell. 2006 Jan 20; 21(2):201-14. PMID: 16427010.
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    14. Adams MM, Wang B, Xia Z, Morales JC, Lu X, Donehower LA, Bochar DA, Elledge SJ, Carpenter PB. 53BP1 oligomerization is independent of its methylation by PRMT1. Cell Cycle. 2005 Dec; 4(12):1854-61. PMID: 16294047.
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    15. Ares Valdés Y, Amador Sandoval B, Morales JC, Alonso Domínguez F, Carballo Velásquez L, Fragas Valdés R, Shou Rodríguez A. [The role of CT scan in the diagnosis of renal cell carcinoma]. Arch Esp Urol. 2004 Sep; 57(7):737-42. PMID: 15536955.
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    16. Morales JC, Carpenter PB. Breaking in a new function for casein kinase 2. Sci Aging Knowledge Environ. 2004 Jun 02; 2004(22):pe24. PMID: 15175499.
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    17. Manis JP, Morales JC, Xia Z, Kutok JL, Alt FW, Carpenter PB. 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination. Nat Immunol. 2004 May; 5(5):481-7. PMID: 15077110.
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    18. Morales JC, Xia Z, Lu T, Aldrich MB, Wang B, Rosales C, Kellems RE, Hittelman WN, Elledge SJ, Carpenter PB. Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability. J Biol Chem. 2003 Apr 25; 278(17):14971-7. PMID: 12578828.
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    19. Fernandez-Capetillo O, Chen HT, Celeste A, Ward I, Romanienko PJ, Morales JC, Naka K, Xia Z, Camerini-Otero RD, Motoyama N, Carpenter PB, Bonner WM, Chen J, Nussenzweig A. DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1. Nat Cell Biol. 2002 Dec; 4(12):993-7. PMID: 12447390.
      View in: PubMed
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