Synaptic Transmission

"Synaptic Transmission" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.

Descriptor ID	D009435
MeSH Number(s)	G02.111.820.850 G04.835.850 G07.265.880 G11.561.830
Concept/Terms	Synaptic Transmission Synaptic Transmission Neural Transmission Neurotransmission Transmission, Neural Transmission, Synaptic

Below are MeSH descriptors whose meaning is more general than "Synaptic Transmission".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Signal Transduction [G02.111.820]
Synaptic Transmission [G02.111.820.850]
Cell Physiological Phenomena [G04]
Signal Transduction [G04.835]
Synaptic Transmission [G04.835.850]
Physiological Phenomena [G07]
Electrophysiological Phenomena [G07.265]
Synaptic Transmission [G07.265.880]
Musculoskeletal and Neural Physiological Phenomena [G11]
Nervous System Physiological Phenomena [G11.561]
Synaptic Transmission [G11.561.830]

Below are MeSH descriptors whose meaning is related to "Synaptic Transmission".

Below are MeSH descriptors whose meaning is more specific than "Synaptic Transmission".

Synaptic Transmission
Postsynaptic Potential Summation

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Synaptic Transmission" by people in this website by year, and whether "Synaptic Transmission" was a major or minor topic of these publications.

Bar chart showing 29 publications over 16 distinct years, with a maximum of 5 publications in 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	0	1
1998	1	0	1
2002	1	0	1
2003	0	1	1
2005	1	3	4
2006	0	1	1
2007	0	3	3
2009	2	1	3
2010	0	1	1
2011	1	0	1
2012	1	1	2
2013	0	1	1
2014	1	1	2
2015	0	1	1
2017	0	1	1
2019	2	3	5

Below are the most recent publications written about "Synaptic Transmission" by people in Profiles.

Hori T, Eguchi K, Wang HY, Miyasaka T, Guillaud L, Taoufiq Z, Mahapatra S, Yamada H, Takei K, Takahashi T. Microtubule assembly by tau impairs endocytosis and neurotransmission via dynamin sequestration in Alzheimer's disease synapse model. Elife. 2022 Apr 26; 11.

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Ardell JL, Foreman RD, Armour JA, Shivkumar K. Cardiac sympathectomy and spinal cord stimulation attenuate reflex-mediated norepinephrine release during ischemia preventing ventricular fibrillation. JCI Insight. 2019 12 05; 4(23).

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Tschumi CW, Daszkowski AW, Sharpe AL, Trzeciak M, Beckstead MJ. A history of ethanol drinking increases locomotor stimulation and blunts enhancement of dendritic dopamine transmission by methamphetamine. Addict Biol. 2020 07; 25(4):e12763.

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Lee YI, Kim YG, Pyeon HJ, Ahn JC, Logan S, Orock A, Joo KM, Lorincz A, Deák F. Dysregulation of the SNARE-binding protein Munc18-1 impairs BDNF secretion and synaptic neurotransmission: a novel interventional target to protect the aging brain. Geroscience. 2019 04; 41(2):109-123.

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Troyano-Rodriguez E, Wirsig-Wiechmann CR, Ahmad M. Neuroligin-2 Determines Inhibitory Synaptic Transmission in the Lateral Septum to Optimize Stress-Induced Neuronal Activation and Avoidance Behavior. Biol Psychiatry. 2019 06 15; 85(12):1046-1055.

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Rice HC, de Malmazet D, Schreurs A, Frere S, Van Molle I, Volkov AN, Creemers E, Vertkin I, Nys J, Ranaivoson FM, Comoletti D, Savas JN, Remaut H, Balschun D, Wierda KD, Slutsky I, Farrow K, De Strooper B, de Wit J. Secreted amyloid-ß precursor protein functions as a GABABR1a ligand to modulate synaptic transmission. Science. 2019 01 11; 363(6423).

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Orock A, Logan S, Deak F. Munc18-1 haploinsufficiency impairs learning and memory by reduced synaptic vesicular release in a model of Ohtahara syndrome. Mol Cell Neurosci. 2018 04; 88:33-42.

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Edwards SL, Yorks RM, Morrison LM, Hoover CM, Miller KG. Synapse-Assembly Proteins Maintain Synaptic Vesicle Cluster Stability and Regulate Synaptic Vesicle Transport in Caenorhabditis elegans. Genetics. 2015 Sep; 201(1):91-116.

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Bennett LD, Hopiavuori BR, Brush RS, Chan M, Van Hook MJ, Thoreson WB, Anderson RE. Examination of VLC-PUFA-deficient photoreceptor terminals. Invest Ophthalmol Vis Sci. 2014 Apr 24; 55(7):4063-72.

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Bulgari D, Zhou C, Hewes RS, Deitcher DL, Levitan ES. Vesicle capture, not delivery, scales up neuropeptide storage in neuroendocrine terminals. Proc Natl Acad Sci U S A. 2014 Mar 04; 111(9):3597-601.

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