"Poly I-C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interferon inducer consisting of a synthetic, mismatched double-stranded RNA. The polymer is made of one strand each of polyinosinic acid and polycytidylic acid.
| Descriptor ID |
D011070
|
| MeSH Number(s) |
D13.695.578.550.560.600 D13.695.578.550.650.600
|
| Concept/Terms |
Poly I-C- Poly I-C
- Poly I C
- Poly(I-C)
- Polyriboinosinic-Polyribocytidylic Acid
- Polyriboinosinic Polyribocytidylic Acid
- Polyribose Inosin-Cytidil
- Inosin-Cytidil, Polyribose
- Polyribose Inosin Cytidil
- Poly(rI).Poly(rC)
- Polyinosinic-Polycytidylic Acid
- Polyinosinic Polycytidylic Acid
- Polyinosinic-Polycytidylic Acid (High MW)
|
Below are MeSH descriptors whose meaning is more general than "Poly I-C".
Below are MeSH descriptors whose meaning is more specific than "Poly I-C".
This graph shows the total number of publications written about "Poly I-C" by people in this website by year, and whether "Poly I-C" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Poly I-C" by people in Profiles.
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Influence of poly(I:C) variability on thermoregulation, immune responses and pregnancy outcomes in mouse models of maternal immune activation. Brain Behav Immun. 2019 08; 80:406-418.
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Combination of mAb-AR20.5, anti-PD-L1 and PolyICLC inhibits tumor progression and prolongs survival of MUC1.Tg mice challenged with pancreatic tumors. Cancer Immunol Immunother. 2018 Mar; 67(3):445-457.
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Interferon-e protects the female reproductive tract from viral and bacterial infection. Science. 2013 Mar 01; 339(6123):1088-92.
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Salivary gland hypofunction induced by activation of innate immunity is dependent on type I interferon signaling. J Oral Pathol Med. 2013 Jan; 42(1):66-72.
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Activation of innate immunity accelerates sialoadenitis in a mouse model for Sjögren's syndrome-like disease. Oral Dis. 2011 Nov; 17(8):801-7.
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Activation of innate immune responses through Toll-like receptor 3 causes a rapid loss of salivary gland function. J Oral Pathol Med. 2009 Jan; 38(1):42-7.
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Alcohol consumption suppresses metastasis of B16-BL6 melanoma in mice. Clin Exp Metastasis. 1993 Mar; 11(2):191-9.