Phosphoadenosine Phosphosulfate
"Phosphoadenosine Phosphosulfate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
3'-Phosphoadenosine-5'-phosphosulfate. Key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate. It is formed from sulfate ion and ATP in a two-step process. This compound also is an important step in the process of sulfur fixation in plants and microorganisms.
| Descriptor ID |
D010724
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| MeSH Number(s) |
D03.633.100.759.646.138.850 D13.695.667.138.850 D13.695.827.068.850
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| Concept/Terms |
Phosphoadenosine Phosphosulfate- Phosphoadenosine Phosphosulfate
- Phosphosulfate, Phosphoadenosine
- Adenosine-3'-phosphate-5'-Phosphosulfate
- Adenosine 3' phosphate 5' Phosphosulfate
|
Below are MeSH descriptors whose meaning is more general than "Phosphoadenosine Phosphosulfate".
Below are MeSH descriptors whose meaning is more specific than "Phosphoadenosine Phosphosulfate".
This graph shows the total number of publications written about "Phosphoadenosine Phosphosulfate" by people in this website by year, and whether "Phosphoadenosine Phosphosulfate" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phosphoadenosine Phosphosulfate" by people in Profiles.
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Reaction product affinity regulates activation of human sulfotransferase 1A1 PAP sulfation. Arch Biochem Biophys. 2011 Feb 15; 506(2):137-41.
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para-Nitrophenyl sulfate activation of human sulfotransferase 1A1 is consistent with intercepting the E[middle dot]PAP complex and reformation of E[middle dot]PAPS. J Biol Chem. 2009 Oct 23; 284(43):29357-64.
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Isotope exchange at equilibrium indicates a steady state ordered kinetic mechanism for human sulfotransferase. Biochemistry. 2008 Nov 11; 47(45):11894-9.
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Sulfation of acetaminophen in isolated rat hepatocytes. Relationship to sulfate ion concentrations and intracellular levels of 3'-phosphoadenosine-5'-phosphosulfate. Drug Metab Dispos. 1988 Sep-Oct; 16(5):712-5.
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Diminished rates of glucuronidation and sulfation in perfused rat liver after chronic ethanol administration. Biochem Pharmacol. 1986 Feb 01; 35(3):439-47.