"Serine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
| Descriptor ID |
D012694
|
| MeSH Number(s) |
D12.125.154.800
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Serine".
Below are MeSH descriptors whose meaning is more specific than "Serine".
This graph shows the total number of publications written about "Serine" by people in this website by year, and whether "Serine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 0 | 1 |
| 1993 | 0 | 2 | 2 |
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 3 | 3 |
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 2 | 3 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 2 | 0 | 2 |
| 2004 | 1 | 1 | 2 |
| 2005 | 0 | 5 | 5 |
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
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Below are the most recent publications written about "Serine" by people in Profiles.
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Wang Y, Hoeppner LH, Angom RS, Wang E, Dutta S, Doeppler HR, Wang F, Shen T, Scarisbrick IA, Guha S, Storz P, Bhattacharya R, Mukhopadhyay D. Protein kinase D up-regulates transcription of VEGF receptor-2 in endothelial cells by suppressing nuclear localization of the transcription factor AP2ß. J Biol Chem. 2019 10 25; 294(43):15759-15767.
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Seibert M, Krüger M, Watson NA, Sen O, Daum JR, Slotman JA, Braun T, Houtsmuller AB, Gorbsky GJ, Jacob R, Kracht M, Higgins JMG, Schmitz ML. CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation. J Cell Biol. 2019 04 01; 218(4):1164-1181.
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Bryant-Hudson KM, Shakir SM, Ballard JD. Autoregulatory characteristics of a Bacillus anthracis serine/threonine kinase. J Bacteriol. 2011 Apr; 193(8):1833-42.
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Kanan Y, Matsumoto H, Song H, Sokolov M, Anderson RE, Rajala RV. Serine/threonine kinase akt activation regulates the activity of retinal serine/threonine phosphatases, PHLPP and PHLPPL. J Neurochem. 2010 Apr; 113(2):477-88.
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Karsten WE, Cook PF. Detection of a gem-diamine and a stable quinonoid intermediate in the reaction catalyzed by serine-glyoxylate aminotransferase from Hyphomicrobium methylovorum. Biochim Biophys Acta. 2009 Jun; 1790(6):575-80.
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Liang S, Wei FY, Wu YM, Tanabe K, Abe T, Oda Y, Yoshida Y, Yamada H, Matsui H, Tomizawa K, Takei K. Major Cdk5-dependent phosphorylation sites of amphiphysin 1 are implicated in the regulation of the membrane binding and endocytosis. J Neurochem. 2007 Sep; 102(5):1466-1476.
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Zhang XQ, Ahlers BA, Tucker AL, Song J, Wang J, Moorman JR, Mounsey JP, Carl LL, Rothblum LI, Cheung JY. Phospholemman inhibition of the cardiac Na+/Ca2+ exchanger. Role of phosphorylation. J Biol Chem. 2006 Mar 24; 281(12):7784-92.
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Karsten WE, Ohshiro T, Izumi Y, Cook PF. Reaction of serine-glyoxylate aminotransferase with the alternative substrate ketomalonate indicates rate-limiting protonation of a quinonoid intermediate. Biochemistry. 2005 Dec 06; 44(48):15930-6.
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Yun BG, Matts RL. Hsp90 functions to balance the phosphorylation state of Akt during C2C12 myoblast differentiation. Cell Signal. 2005 Dec; 17(12):1477-85.
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Kothapalli N, Sarath G, Zempleni J. Biotinylation of K12 in histone H4 decreases in response to DNA double-strand breaks in human JAr choriocarcinoma cells. J Nutr. 2005 Oct; 135(10):2337-42.