Synaptic Vesicles

"Synaptic Vesicles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Membrane-bound compartments which contain transmitter molecules. Synaptic vesicles are concentrated at presynaptic terminals. They actively sequester transmitter molecules from the cytoplasm. In at least some synapses, transmitter release occurs by fusion of these vesicles with the presynaptic membrane, followed by exocytosis of their contents.

Descriptor ID	D013572
MeSH Number(s)	A08.850.840 A11.284.430.214.190.875.190.880.830
Concept/Terms	Synaptic Vesicles Synaptic Vesicles Synaptic Vesicle Vesicle, Synaptic Vesicles, Synaptic

Below are MeSH descriptors whose meaning is more general than "Synaptic Vesicles".

Anatomy [A]
Nervous System [A08]
Synapses [A08.850]
Synaptic Vesicles [A08.850.840]
Cells [A11]
Cellular Structures [A11.284]
Intracellular Space [A11.284.430]
Cytoplasm [A11.284.430.214]
Cytoplasmic Structures [A11.284.430.214.190]
Organelles [A11.284.430.214.190.875]
Cytoplasmic Vesicles [A11.284.430.214.190.875.190]
Transport Vesicles [A11.284.430.214.190.875.190.880]
Synaptic Vesicles [A11.284.430.214.190.875.190.880.830]

Below are MeSH descriptors whose meaning is related to "Synaptic Vesicles".

Below are MeSH descriptors whose meaning is more specific than "Synaptic Vesicles".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Synaptic Vesicles" by people in this website by year, and whether "Synaptic Vesicles" was a major or minor topic of these publications.

Bar chart showing 12 publications over 9 distinct years, with a maximum of 2 publications in 2005 and 2017 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	0	1	1
2004	0	1	1
2005	2	0	2
2007	1	0	1
2012	1	0	1
2015	1	0	1
2017	1	1	2
2019	0	2	2

Below are the most recent publications written about "Synaptic Vesicles" by people in Profiles.

Hori T, Eguchi K, Wang HY, Miyasaka T, Guillaud L, Taoufiq Z, Mahapatra S, Yamada H, Takei K, Takahashi T. Microtubule assembly by tau impairs endocytosis and neurotransmission via dynamin sequestration in Alzheimer's disease synapse model. Elife. 2022 Apr 26; 11.

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Lee YI, Kim YG, Pyeon HJ, Ahn JC, Logan S, Orock A, Joo KM, Lorincz A, Deák F. Dysregulation of the SNARE-binding protein Munc18-1 impairs BDNF secretion and synaptic neurotransmission: a novel interventional target to protect the aging brain. Geroscience. 2019 04; 41(2):109-123.

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Rice HC, de Malmazet D, Schreurs A, Frere S, Van Molle I, Volkov AN, Creemers E, Vertkin I, Nys J, Ranaivoson FM, Comoletti D, Savas JN, Remaut H, Balschun D, Wierda KD, Slutsky I, Farrow K, De Strooper B, de Wit J. Secreted amyloid-ß precursor protein functions as a GABABR1a ligand to modulate synaptic transmission. Science. 2019 01 11; 363(6423).

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Piccini A, Castroflorio E, Valente P, Guarnieri FC, Aprile D, Michetti C, Bramini M, Giansante G, Pinto B, Savardi A, Cesca F, Bachi A, Cattaneo A, Wren JD, Fassio A, Valtorta F, Benfenati F, Giovedì S. APache Is an AP2-Interacting Protein Involved in Synaptic Vesicle Trafficking and Neuronal Development. Cell Rep. 2017 Dec 19; 21(12):3596-3611.

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Orock A, Logan S, Deak F. Munc18-1 haploinsufficiency impairs learning and memory by reduced synaptic vesicular release in a model of Ohtahara syndrome. Mol Cell Neurosci. 2018 04; 88:33-42.

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Edwards SL, Yorks RM, Morrison LM, Hoover CM, Miller KG. Synapse-Assembly Proteins Maintain Synaptic Vesicle Cluster Stability and Regulate Synaptic Vesicle Transport in Caenorhabditis elegans. Genetics. 2015 Sep; 201(1):91-116.

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Mullen GP, Grundahl KM, Gu M, Watanabe S, Hobson RJ, Crowell JA, McManus JR, Mathews EA, Jorgensen EM, Rand JB. UNC-41/stonin functions with AP2 to recycle synaptic vesicles in Caenorhabditis elegans. PLoS One. 2012; 7(7):e40095.

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Shakiryanova D, Klose MK, Zhou Y, Gu T, Deitcher DL, Atwood HL, Hewes RS, Levitan ES. Presynaptic ryanodine receptor-activated calmodulin kinase II increases vesicle mobility and potentiates neuropeptide release. J Neurosci. 2007 Jul 18; 27(29):7799-806.

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Sherry DM, Heidelberger R. Distribution of proteins associated with synaptic vesicle endocytosis in the mouse and goldfish retina. J Comp Neurol. 2005 Apr 18; 484(4):440-57.

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Shakiryanova D, Tully A, Hewes RS, Deitcher DL, Levitan ES. Activity-dependent liberation of synaptic neuropeptide vesicles. Nat Neurosci. 2005 Feb; 8(2):173-8.

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