"Synaptic Vesicles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane-bound compartments which contain transmitter molecules. Synaptic vesicles are concentrated at presynaptic terminals. They actively sequester transmitter molecules from the cytoplasm. In at least some synapses, transmitter release occurs by fusion of these vesicles with the presynaptic membrane, followed by exocytosis of their contents.
| Descriptor ID |
D013572
|
| MeSH Number(s) |
A08.850.840 A11.284.430.214.190.875.190.880.830
|
| Concept/Terms |
Synaptic Vesicles- Synaptic Vesicles
- Synaptic Vesicle
- Vesicle, Synaptic
- Vesicles, Synaptic
|
Below are MeSH descriptors whose meaning is more general than "Synaptic Vesicles".
Below are MeSH descriptors whose meaning is more specific than "Synaptic Vesicles".
This graph shows the total number of publications written about "Synaptic Vesicles" by people in this website by year, and whether "Synaptic Vesicles" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2017 | 1 | 1 | 2 |
| 2019 | 0 | 2 | 2 |
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Below are the most recent publications written about "Synaptic Vesicles" by people in Profiles.
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Dysregulation of the SNARE-binding protein Munc18-1 impairs BDNF secretion and synaptic neurotransmission: a novel interventional target to protect the aging brain. Geroscience. 2019 04; 41(2):109-123.
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Secreted amyloid-ß precursor protein functions as a GABABR1a ligand to modulate synaptic transmission. Science. 2019 01 11; 363(6423).
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APache Is an AP2-Interacting Protein Involved in Synaptic Vesicle Trafficking and Neuronal Development. Cell Rep. 2017 Dec 19; 21(12):3596-3611.
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Munc18-1 haploinsufficiency impairs learning and memory by reduced synaptic vesicular release in a model of Ohtahara syndrome. Mol Cell Neurosci. 2018 04; 88:33-42.
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Synapse-Assembly Proteins Maintain Synaptic Vesicle Cluster Stability and Regulate Synaptic Vesicle Transport in Caenorhabditis elegans. Genetics. 2015 Sep; 201(1):91-116.
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Coarse-Grained Model of SNARE-Mediated Docking. Biophys J. 2015 May 05; 108(9):2258-69.
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UNC-41/stonin functions with AP2 to recycle synaptic vesicles in Caenorhabditis elegans. PLoS One. 2012; 7(7):e40095.
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Presynaptic ryanodine receptor-activated calmodulin kinase II increases vesicle mobility and potentiates neuropeptide release. J Neurosci. 2007 Jul 18; 27(29):7799-806.
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Distribution of proteins associated with synaptic vesicle endocytosis in the mouse and goldfish retina. J Comp Neurol. 2005 Apr 18; 484(4):440-57.
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Activity-dependent liberation of synaptic neuropeptide vesicles. Nat Neurosci. 2005 Feb; 8(2):173-8.