"Quinine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
Below are MeSH descriptors whose meaning is more general than "Quinine".
Below are MeSH descriptors whose meaning is more specific than "Quinine".
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Below are the most recent publications written about "Quinine" by people in Profiles.
Mouse Parabrachial Neurons Signal a Relationship between Bitter Taste and Nociceptive Stimuli. J Neurosci. 2019 02 27; 39(9):1631-1648.
Quinine-Induced Thrombotic Microangiopathy: A Report of 19 Patients. Am J Kidney Dis. 2017 Nov; 70(5):686-695.
After the Party's Over. N Engl J Med. 2017 Jan 05; 376(1):74-80.
Diversity and severity of adverse reactions to quinine: A systematic review. Am J Hematol. 2016 May; 91(5):461-6.
Identification of Compounds with Efficacy against Malaria Parasites from Common North American Plants. J Nat Prod. 2016 Mar 25; 79(3):490-8.
Drug-induced thrombotic microangiopathy: Experience of the Oklahoma Registry and the BloodCenter of Wisconsin. Am J Hematol. 2015 May; 90(5):406-10.
Chemosensory responsiveness to ethanol and its individual sensory components in alcohol-preferring, alcohol-nonpreferring and genetically heterogeneous rats. Addict Biol. 2012 Mar; 17(2):423-36.
Ethanol concentration-dependent effects and the role of stress on ethanol drinking in corticotropin-releasing factor type 1 and double type 1 and 2 receptor knockout mice. Psychopharmacology (Berl). 2011 Nov; 218(1):169-77.
Different disparities of gender and race among the thrombotic thrombocytopenic purpura and hemolytic-uremic syndromes. Am J Hematol. 2010 Nov; 85(11):844-7.
T1r3 taste receptor involvement in gustatory neural responses to ethanol and oral ethanol preference. Physiol Genomics. 2010 May; 41(3):232-43.