An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)

Descriptor ID	D015624
MeSH Number(s)	C04.588.614.550.225 C04.730.856.225 C10.114.468 C10.574.781.500 C10.668.758.450 C20.111.258.350
Concept/Terms	Lambert-Eaton Myasthenic Syndrome Lambert-Eaton Myasthenic Syndrome Lambert Eaton Myasthenic Syndrome Eaton-Lambert Myasthenic Syndrome Eaton Lambert Myasthenic Syndrome Myasthenic Syndrome, Eaton-Lambert Syndrome, Eaton-Lambert Myasthenic Myasthenic Syndrome, Lambert-Eaton Myasthenic Syndrome, Lambert Eaton Syndrome, Lambert-Eaton Myasthenic Myopathic-Myasthenic Syndrome of Lambert-Eaton Lambert-Eaton Myopathic-Myasthenic Syndrome Lambert-Eaton Myopathic-Myasthenic Syndromes Lambert-Eaton Syndrome Lambert Eaton Syndrome Syndrome, Lambert-Eaton Myasthenic-Myopathic Syndrome of Lambert-Eaton Lambert-Eaton Myasthenic-Myopathic Syndrome Lambert-Eaton Myasthenic-Myopathic Syndromes Myasthenic Myopathic Syndrome of Lambert Eaton Myopathic-Myasthenic Syndrome of Eaton-Lambert Eaton-Lambert Myopathic-Myasthenic Syndrome Eaton-Lambert Myopathic-Myasthenic Syndromes Myopathic Myasthenic Syndrome of Eaton Lambert Eaton-Lambert Syndrome Eaton Lambert Syndrome Syndrome, Eaton-Lambert Myasthenic-Myopathic Syndrome of Eaton-Lambert Eaton-Lambert Myasthenic-Myopathic Syndrome Myasthenic Myopathic Syndrome of Eaton Lambert

Below are MeSH descriptors whose meaning is more general than "Lambert-Eaton Myasthenic Syndrome".

Below are MeSH descriptors whose meaning is related to "Lambert-Eaton Myasthenic Syndrome".

Below are MeSH descriptors whose meaning is more specific than "Lambert-Eaton Myasthenic Syndrome".