"Giant Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multinucleated masses produced by the fusion of many cells; often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of the HIV virus binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus.
- Giant Cells
- Cell, Giant
- Cells, Giant
- Giant Cell
- Giant Cells, Multinucleated
- Cell, Multinucleated Giant
- Cells, Multinucleated Giant
- Giant Cell, Multinucleated
- Multinucleated Giant Cell
- Multinucleated Giant Cells
Below are MeSH descriptors whose meaning is more general than "Giant Cells".
Below are MeSH descriptors whose meaning is more specific than "Giant Cells".
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Below are the most recent publications written about "Giant Cells" by people in Profiles.
Giant cell myocarditis: a rare cardiovascular manifestation in a patient with systemic lupus erythematosus. Lupus. 2005; 14(2):166-9.
Pathologic quiz case: pigmented lesion on the mons pubis of a 17-year-old girl. Compound nevus with features of milk mine nevus. Arch Pathol Lab Med. 2003 Sep; 127(9):e391-2.
The compound DATEM inhibits respiratory syncytial virus fusion activity with epithelial cells. Antiviral Res. 2003 Apr; 58(2):115-24.
Multinucleated giant stromal tumor of the omentum: report of a case with immunohistochemical and ultrastructural investigation. Ultrastruct Pathol. 1996 Jan-Feb; 20(1):89-99.