"Arylsulfotransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sulfotransferase that catalyzes the sulfation of a phenol in the presence of 3'-phosphoadenylylsulfate as sulfate donor to yield an aryl sulfate and adenosine 3',5'-bisphosphate. A number of aromatic compounds can act as acceptors; however, organic hydroxylamines are not substrates. Sulfate conjugation by this enzyme is a major pathway for the biotransformation of phenolic and catechol drugs as well as neurotransmitters. EC 2.8.2.1.
Descriptor ID |
D015239
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MeSH Number(s) |
D08.811.913.817.400.300
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Concept/Terms |
Arylsulfotransferase- Arylsulfotransferase
- Aryl Sulfotransferase
- Sulfotransferase, Aryl
- Phenolsulfokinase
- Phenol Sulfotransferase
- Sulfotransferase, Phenol
- Sulfokinase
- Phenol Sulfokinase
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Below are MeSH descriptors whose meaning is more general than "Arylsulfotransferase".
Below are MeSH descriptors whose meaning is more specific than "Arylsulfotransferase".
This graph shows the total number of publications written about "Arylsulfotransferase" by people in this website by year, and whether "Arylsulfotransferase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Arylsulfotransferase" by people in Profiles.
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Reaction product affinity regulates activation of human sulfotransferase 1A1 PAP sulfation. Arch Biochem Biophys. 2011 Feb 15; 506(2):137-41.
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para-Nitrophenyl sulfate activation of human sulfotransferase 1A1 is consistent with intercepting the E[middle dot]PAP complex and reformation of E[middle dot]PAPS. J Biol Chem. 2009 Oct 23; 284(43):29357-64.
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Evidence of two separate mechanisms for the decrease in aryl sulfotransferase activity in rat liver during early stages of 2-acetylaminofluorene-induced hepatocarcinogenesis. Mol Carcinog. 1994 Jan; 9(1):2-9.
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Diminished rates of glucuronidation and sulfation in perfused rat liver after chronic ethanol administration. Biochem Pharmacol. 1986 Feb 01; 35(3):439-47.