Gene Rearrangement, B-Lymphocyte, Heavy Chain
"Gene Rearrangement, B-Lymphocyte, Heavy Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ordered rearrangement of B-lymphocyte variable gene regions of the IMMUNOGLOBULIN HEAVY CHAINS, thereby contributing to antibody diversity. It occurs during the first stage of differentiation of the IMMATURE B-LYMPHOCYTES.
| Descriptor ID |
D015326
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| MeSH Number(s) |
G05.344.401.501 G12.500.274.501
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| Concept/Terms |
Gene Rearrangement, B-Lymphocyte, Heavy Chain- Gene Rearrangement, B-Lymphocyte, Heavy Chain
- B-Cell Heavy Chain Gene Rearrangement
- B-Lymphocyte Heavy Chain Gene Rearrangement
- B Cell Heavy Chain Gene Rearrangement
- B Lymphocyte Heavy Chain Gene Rearrangement
|
Below are MeSH descriptors whose meaning is more general than "Gene Rearrangement, B-Lymphocyte, Heavy Chain".
Below are MeSH descriptors whose meaning is more specific than "Gene Rearrangement, B-Lymphocyte, Heavy Chain".
This graph shows the total number of publications written about "Gene Rearrangement, B-Lymphocyte, Heavy Chain" by people in this website by year, and whether "Gene Rearrangement, B-Lymphocyte, Heavy Chain" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gene Rearrangement, B-Lymphocyte, Heavy Chain" by people in Profiles.
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High frequency of matrix attachment regions and cut-like protein x/CCAAT-displacement protein and B cell regulator of IgH transcription binding sites flanking Ig V region genes. J Immunol. 2002 Sep 01; 169(5):2477-87.
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Relatively normal human lymphopoiesis but rapid turnover of newly formed B cells in transplanted nonobese diabetic/SCID mice. J Immunol. 2001 Sep 15; 167(6):3033-42.
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Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors. Immunity. 1999 Jun; 10(6):713-22.