"DNA Probes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.
- DNA Probes
- Probes, DNA
- DNA Hybridization Probes
- Hybridization Probes, DNA
- Probes, DNA Hybridization
Below are MeSH descriptors whose meaning is more general than "DNA Probes".
Below are MeSH descriptors whose meaning is more specific than "DNA Probes".
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Below are the most recent publications written about "DNA Probes" by people in Profiles.
A Label-Free Photoluminescence Genosensor Using Nanostructured Magnesium Oxide for Cholera Detection. Sci Rep. 2015 Nov 27; 5:17384.
Evaluation of three real-time PCR assays for detection of Mycoplasma pneumoniae in an outbreak investigation. J Clin Microbiol. 2008 Sep; 46(9):3116-8.
A common 1317TC polymorphism in MTHFR can lead to erroneous 1298AC genotyping by PCR-RE and TaqMan probe assays. Genet Test. 2007; 11(2):167-73.
Abnormal melt curve profile during prothrombin 20210G --> A analysis due to the 20209C --> T variant. Blood Coagul Fibrinolysis. 2006 Oct; 17(7):599-602.
Reproducibility, sources of variability, pooling, and sample size: important considerations for the design of high-density oligonucleotide array experiments. J Gerontol A Biol Sci Med Sci. 2004 Apr; 59(4):306-15.
Real-time PCR quantification of rbcL (ribulose-1,5-bisphosphate carboxylase/oxygenase) mRNA in diatoms and pelagophytes. Appl Environ Microbiol. 2002 Aug; 68(8):3771-9.
Rapid prenatal diagnosis of trisomies 13, 18, 21 and sex chromosome anomalies by fluorescence in situ hybridization: a year's experience. J Okla State Med Assoc. 2002 Apr; 95(4):244-6.
Familial pheochromocytoma due to mutant von Hippel-Lindau disease gene. Arch Intern Med. 1997 Jun 23; 157(12):1390-1.
Haplotype analysis of two APOA1/MspI polymorphisms in relation to plasma levels of apo A-I and HDL-cholesterol. Atherosclerosis. 1996 Dec 20; 127(2):255-62.
Nonradioactive colony lift-hybridization assay for detection of Bordetella bronchiseptica infection in swine. J Clin Microbiol. 1995 Oct; 33(10):2675-8.