Cyclic AMP Response Element-Binding Protein
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"Cyclic AMP Response Element-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A protein that has been shown to function as a calcium-regulated transcription factor as well as a substrate for depolarization-activated CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES. This protein functions to integrate both calcium and cAMP signals.
    
			
			
				
				
					
						| Descriptor ID | 
										
							D017362
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						| MeSH Number(s) | 
						
							 D12.776.260.108.184 D12.776.930.127.184 
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						| Concept/Terms | 
						
							Cyclic AMP Response Element-Binding Protein- Cyclic AMP Response Element-Binding Protein
 - CREB Protein
 - DNA-Binding Protein, Cyclic AMP-Responsive
 - DNA Binding Protein, Cyclic AMP Responsive
 - cAMP Response Element-Binding Protein
 - cAMP Response Element Binding Protein
 - Cyclic AMP-Responsive DNA-Binding Protein
 - Cyclic AMP Responsive DNA Binding Protein
 
  
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				Below are MeSH descriptors whose meaning is more general than "Cyclic AMP Response Element-Binding Protein".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Cyclic AMP Response Element-Binding Protein".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Cyclic AMP Response Element-Binding Protein" by people in this website by year, and whether "Cyclic AMP Response Element-Binding Protein" was a major or minor topic of these publications. 
				
					
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 1995 | 0 | 1 | 1 | 
| 1996 | 0 | 1 | 1 | 
| 1997 | 0 | 1 | 1 | 
| 1998 | 1 | 0 | 1 | 
| 2000 | 0 | 1 | 1 | 
| 2002 | 0 | 2 | 2 | 
| 2003 | 0 | 1 | 1 | 
| 2007 | 1 | 1 | 2 | 
| 2010 | 0 | 3 | 3 | 
| 2012 | 0 | 1 | 1 | 
| 2013 | 1 | 1 | 2 | 
| 2015 | 1 | 0 | 1 | 
| 2018 | 1 | 0 | 1 | 
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				Below are the most recent publications written about "Cyclic AMP Response Element-Binding Protein" by people in Profiles.
						
					
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Unique, Intersecting, and Overlapping Roles of C/EBP ß and CREB in Cells of the Innate Immune System. Sci Rep. 2018 11 16; 8(1):16931.
															
								 
							
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Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU. Sci Signal. 2015 Mar 03; 8(366):ra23.
															
								 
							
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The gep proto-oncogene Ga12 mediates LPA-stimulated activation of CREB in ovarian cancer cells. Cell Signal. 2014 Jan; 26(1):122-32.
															
								 
							
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Moderate GLUT4 overexpression improves insulin sensitivity and fasting triglyceridemia in high-fat diet-fed transgenic mice. Diabetes. 2013 Jul; 62(7):2249-58.
															
								 
							
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Increased phosphoenolpyruvate carboxykinase gene expression and steatosis during hepatitis C virus subgenome replication: role of nonstructural component 5A and CCAAT/enhancer-binding protein ß. J Biol Chem. 2012 Oct 26; 287(44):37340-51.
															
								 
							
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CRTC3 links catecholamine signalling to energy balance. Nature. 2010 Dec 16; 468(7326):933-9.
															
								 
							
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C/EBPß is AMP kinase sensitive and up-regulates PEPCK in response to ER stress in hepatoma cells. Mol Cell Endocrinol. 2011 Jan 01; 331(1):102-8.
															
								 
							
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Irradiation induces regionally specific alterations in pro-inflammatory environments in rat brain. Int J Radiat Biol. 2010 Feb; 86(2):132-44.
															
								 
							
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Chronic late-gestation hypoglycemia upregulates hepatic PEPCK associated with increased PGC1alpha mRNA and phosphorylated CREB in fetal sheep. Am J Physiol Endocrinol Metab. 2008 Feb; 294(2):E365-70.
															
								 
							
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Retinal ganglion cell protection by 17-beta-estradiol in a mouse model of inherited glaucoma. Dev Neurobiol. 2007 Apr; 67(5):603-16.