Genotype-dependent impairment of hemoglobin clearance increases oxidative and inflammatory response in human diabetic atherosclerosis.
Purushothaman M, Krishnan P, Purushothaman KR, Baber U, Tarricone A, Perez JS, Wiley J, Kini A, Sharma SK, Fuster V, Moreno PR. Genotype-dependent impairment of hemoglobin clearance increases oxidative and inflammatory response in human diabetic atherosclerosis. Arterioscler Thromb Vasc Biol. 2012 Nov; 32(11):2769-75.
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Actins
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Actins
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Aged
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Aged
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Antigens, CD
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Antigens, CD
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Antigens, Differentiation, Myelomonocytic
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Antigens, Differentiation, Myelomonocytic
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Atherosclerosis
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Atherosclerosis
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Biomarkers
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Biomarkers
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Case-Control Studies
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Case-Control Studies
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Diabetes Mellitus
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Diabetes Mellitus
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Diabetic Angiopathies
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Diabetic Angiopathies
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Female
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Female
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Genotype
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Genotype
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Haptoglobins
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Haptoglobins
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Heme Oxygenase-1
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Heme Oxygenase-1
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Hemoglobins
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Hemoglobins
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Humans
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Humans
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Inflammation
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Inflammation
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Interleukin-10
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Interleukin-10
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Iron
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Iron
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Male
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Male
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Middle Aged
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Middle Aged
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Neovascularization, Pathologic
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Neovascularization, Pathologic
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Oxidative Stress
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Oxidative Stress
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Peroxidase
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Peroxidase
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Phenotype
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Phenotype
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Prospective Studies
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Prospective Studies
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Receptors, Cell Surface
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Receptors, Cell Surface
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Vascular Cell Adhesion Molecule-1
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Vascular Cell Adhesion Molecule-1