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Adam S Asch

TitleProf
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentMedicine Hematology/Oncology
AddressOUCI 6
800 NE 10th St
Oklahoma City OK 73104
Phone405/271-4022
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    Collapse Research 
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    K08HL001567     (ASCH, ADAM S)Aug 1, 1985 - Jul 31, 1990
    NIH
    THE CELLULAR BIOLOGY OF THROMBOSPONDIN
    Role: Principal Investigator

    K04HL002541     (ASCH, ADAM S)Dec 15, 1990 - Nov 30, 1995
    NIH
    STRUCTURE AND FUNCTION OF THE TSP-GPIV SYSTEM
    Role: Principal Investigator

    R01HL044389     (ASCH, ADAM S)Aug 1, 1991 - Jul 31, 1995
    NIH
    STRUCTURE/FUNCTION OF THE TSP--CD36 SYSTEM
    Role: Principal Investigator

    R01DK048698     (ASCH, ADAM S)Jan 1, 1997 - Dec 31, 2002
    NIH
    ENDOTHELIAL CELL-STEM CELL INTERACTIONS
    Role: Principal Investigator

    R01NS043883     (ASCH, ADAM S)Sep 30, 2001 - Jul 31, 2006
    NIH
    INDUCTION AND MAINTENANCE OF PLURIPOTENT-PLASTIC STATE
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Rao CV, Xu C, Farooqui M, Zhang Y, Asch AS, Yamada HY. Survival-Critical Genes Associated with Copy Number Alterations in Lung Adenocarcinoma. Cancers (Basel). 2021 May 25; 13(11). PMID: 34070461.
      Citations:    
    2. Corbin JM, Georgescu C, Wren JD, Xu C, Asch AS, Ruiz-Echevarría MJ. Seed-mediated RNA interference of androgen signaling and survival networks induces cell death in prostate cancer cells. Mol Ther Nucleic Acids. 2021 Jun 04; 24:337-351. PMID: 33850637.
      Citations:    
    3. Keruakous AR, Balakrishna P, Schmidt SA, Autry MT, Asch A. Genomic profiling is a supplemental diagnostic and therapeutic modality for hairy cell leukemia variant. Ann Hematol. 2021 Jun; 100(6):1629-1630. PMID: 33433650.
      Citations:    Fields:    
    4. Rao CV, Farooqui M, Madhavaram A, Zhang Y, Asch AS, Yamada HY. GSK3-ARC/Arg3.1 and GSK3-Wnt signaling axes trigger amyloid-ß accumulation and neuroinflammation in middle-aged Shugoshin 1 mice. Aging Cell. 2020 10; 19(10):e13221. PMID: 32857910.
      Citations: 1     Fields:    
    5. Assi HA, Asch AS, Machiorlatti M, Vesely SK, Ibrahimi S. Development of thrombocytopenia is associated with improved survival in patients treated with immunotherapy. Future Sci OA. 2020 Jun 25; 6(7):FSO581. PMID: 32802390.
      Citations:    
    6. Rao CV, Asch AS, Carr DJJ, Yamada HY. "Amyloid-beta accumulation cycle" as a prevention and/or therapy target for Alzheimer's disease. Aging Cell. 2020 03; 19(3):e13109. PMID: 31981470.
      Citations: 6     Fields:    Translation:HumansAnimals
    7. Madka V, Kumar G, Pathuri G, Zhang Y, Lightfoot S, Asch AS, Mohammed A, Steele VE, Rao CV. Bisphosphonates Zometa and Fosamax Synergize with Metformin to Prevent AOM-Induced Colon Cancer in F344 Rat Model. Cancer Prev Res (Phila). 2020 02; 13(2):185-194. PMID: 31699708.
      Citations: 1     Fields:    Translation:HumansAnimals
    8. Georgescu C, Corbin JM, Thibivilliers S, Webb ZD, Zhao YD, Koster J, Fung KM, Asch AS, Wren JD, Ruiz-Echevarría MJ. A TMEFF2-regulated cell cycle derived gene signature is prognostic of recurrence risk in prostate cancer. BMC Cancer. 2019 May 06; 19(1):423. PMID: 31060542.
      Citations: 4     Fields:    Translation:HumansCells
    9. Rao CV, Farooqui M, Asch AS, Yamada HY. Critical role of mitosis in spontaneous late-onset Alzheimer's disease; from a Shugoshin 1 cohesinopathy mouse model. . 2018; 17(19-20):2321-2334. PMID: 30231670.
      Citations:    
    10. Rao CV, Farooqui M, Zhang Y, Asch AS, Yamada HY. Spontaneous development of Alzheimer's disease-associated brain pathology in a Shugoshin-1 mouse cohesinopathy model. Aging Cell. 2018 08; 17(4):e12797. PMID: 29943428.
      Citations: 10     Fields:    Translation:Animals
    11. Mohammed A, Janakiram NB, Madka V, Li M, Asch AS, Rao CV. Current Challenges and Opportunities for Chemoprevention of Pancreatic Cancer. Curr Med Chem. 2018; 25(22):2535-2544. PMID: 28183260.
      Citations: 4     Fields:    Translation:HumansAnimals
    12. Rao CV, Mohammed A, Asch AS, Janakiram NB. Immunoprevention of Pancreatic Cancer. Curr Med Chem. 2018; 25(22):2576-2584. PMID: 28240168.
      Citations: 1     Fields:    Translation:HumansCells
    13. Janakiram NB, Mohammed A, Bryant T, Ritchie R, Stratton N, Jackson L, Lightfoot S, Benbrook DM, Asch AS, Lang ML, Rao CV. Loss of natural killer T cells promotes pancreatic cancer in LSL-KrasG12D/+ mice. Immunology. 2017 09; 152(1):36-51. PMID: 28419443.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    14. Rao CV, Pal S, Mohammed A, Farooqui M, Doescher MP, Asch AS, Yamada HY. Biological effects and epidemiological consequences of arsenic exposure, and reagents that can ameliorate arsenic damage in vivo. Oncotarget. 2017 Aug 22; 8(34):57605-57621. PMID: 28915699.
      Citations: 13     Fields:    
    15. Rao CV, Asch AS, Yamada HY. Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer. Carcinogenesis. 2017 01; 38(1):2-11. PMID: 27838634.
      Citations: 29     Fields:    Translation:HumansCells
    16. Rao CV, Asch AS, Yamada HY. Emerging links among Chromosome Instability (CIN), cancer, and aging. Mol Carcinog. 2017 03; 56(3):791-803. PMID: 27533343.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    17. Park SI, Grover NS, Olajide O, Asch AS, Wall JG, Richards KL, Sobol AL, Deal AM, Ivanova A, Foster MC, Muss HB, Shea TC. A phase II trial of bendamustine in combination with rituximab in older patients with previously untreated diffuse large B-cell lymphoma. Br J Haematol. 2016 Oct; 175(2):281-289. PMID: 27448091.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    18. Datla US, Scovill NC, Brokamp AJ, Kim E, Asch AS, Lee MH. Role of PUF-8/PUF protein in stem cell control, sperm-oocyte decision and cell fate reprogramming. J Cell Physiol. 2014 Oct; 229(10):1306-11. PMID: 24638209.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    19. Kobet RA, Pan X, Zhang B, Pak SC, Asch AS, Lee MH. Caenorhabditis elegans: A Model System for Anti-Cancer Drug Discovery and Therapeutic Target Identification. Biomol Ther (Seoul). 2014 Sep; 22(5):371-83. PMID: 25414766.
      Citations:    
    20. Chen X, Corbin JM, Tipton GJ, Yang LV, Asch AS, Ruiz-Echevarría MJ. The TMEFF2 tumor suppressor modulates integrin expression, RhoA activation and migration of prostate cancer cells. Biochim Biophys Acta. 2014 Jun; 1843(6):1216-24. PMID: 24632071.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    21. Green T, Chen X, Ryan S, Asch AS, Ruiz-Echevarría MJ. TMEFF2 and SARDH cooperate to modulate one-carbon metabolism and invasion of prostate cancer cells. Prostate. 2013 Oct; 73(14):1561-75. PMID: 23824605.
      Citations: 16     Fields:    Translation:HumansCells
    22. Dong L, Li Z, Leffler NR, Asch AS, Chi JT, Yang LV. Acidosis activation of the proton-sensing GPR4 receptor stimulates vascular endothelial cell inflammatory responses revealed by transcriptome analysis. PLoS One. 2013; 8(4):e61991. PMID: 23613998.
      Citations: 33     Fields:    Translation:HumansCells
    23. Overcash RF, Chappell VA, Green T, Geyer CB, Asch AS, Ruiz-Echevarría MJ. Androgen signaling promotes translation of TMEFF2 in prostate cancer cells via phosphorylation of the a subunit of the translation initiation factor 2. PLoS One. 2013; 8(2):e55257. PMID: 23405127.
      Citations: 7     Fields:    Translation:HumansCells
    24. Whelan JT, Hollis SE, Cha DS, Asch AS, Lee MH. Post-transcriptional regulation of the Ras-ERK/MAPK signaling pathway. J Cell Physiol. 2012 Mar; 227(3):1235-41. PMID: 21688267.
      Citations: 37     Fields:    Translation:HumansCells
    25. Chen A, Dong L, Leffler NR, Asch AS, Witte ON, Yang LV. Activation of GPR4 by acidosis increases endothelial cell adhesion through the cAMP/Epac pathway. PLoS One. 2011; 6(11):e27586. PMID: 22110680.
      Citations: 43     Fields:    Translation:HumansCells
    26. Chen X, Overcash R, Green T, Hoffman D, Asch AS, Ruiz-Echevarría MJ. The tumor suppressor activity of the transmembrane protein with epidermal growth factor and two follistatin motifs 2 (TMEFF2) correlates with its ability to modulate sarcosine levels. J Biol Chem. 2011 May 06; 286(18):16091-100. PMID: 21393249.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    27. Sigounas G, Hairr JW, Cooke CD, Owen JR, Asch AS, Weidner DA, Wiley JE. Role of benzo[alpha]pyrene in generation of clustered DNA damage in human breast tissue. Free Radic Biol Med. 2010 Jul 01; 49(1):77-87. PMID: 20347033.
      Citations: 3     Fields:    Translation:HumansCells
    28. Wiestner A, Cho HJ, Asch AS, Michelis MA, Zeller JA, Peerschke EI, Weksler BB, Schechter GP. Rituximab in the treatment of acquired factor VIII inhibitors. Blood. 2002 Nov 01; 100(9):3426-8. PMID: 12384448.
      Citations: 28     Fields:    Translation:HumansCells
    29. Griffin E, Re A, Hamel N, Fu C, Bush H, McCaffrey T, Asch AS. A link between diabetes and atherosclerosis: Glucose regulates expression of CD36 at the level of translation. Nat Med. 2001 Jul; 7(7):840-6. PMID: 11433350.
      Citations: 88     Fields:    Translation:HumansCells
    30. Arvanitakis L, Mesri EA, Nador RG, Said JW, Asch AS, Knowles DM, Cesarman E. Establishment and characterization of a primary effusion (body cavity-based) lymphoma cell line (BC-3) harboring kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in the absence of Epstein-Barr virus. Blood. 1996 Oct 01; 88(7):2648-54. PMID: 8839859.
      Citations: 156     Fields:    Translation:HumansCells
    31. Rafii S, Shapiro F, Pettengell R, Ferris B, Nachman RL, Moore MA, Asch AS. Human bone marrow microvascular endothelial cells support long-term proliferation and differentiation of myeloid and megakaryocytic progenitors. Blood. 1995 Nov 01; 86(9):3353-63. PMID: 7579438.
      Citations: 66     Fields:    Translation:HumansCells
    32. Rafii S, Shapiro F, Rimarachin J, Nachman RL, Ferris B, Weksler B, Moore MA, Asch AS. Isolation and characterization of human bone marrow microvascular endothelial cells: hematopoietic progenitor cell adhesion. Blood. 1994 Jul 01; 84(1):10-9. PMID: 7517203.
      Citations: 57     Fields:    Translation:HumansCells
    33. Asch AS, Leung LL, Polley MJ, Nachman RL. Platelet membrane topography: colocalization of thrombospondin and fibrinogen with the glycoprotein IIb-IIIa complex. Blood. 1985 Oct; 66(4):926-34. PMID: 2994782.
      Citations: 13     Fields:    Translation:HumansCells
    34. Nachmias V, Sullender J, Asch A. Shape and cytoplasmic filaments in control and lidocaine-treated human platelets. Blood. 1977 Jul; 50(1):39-53. PMID: 871525.
      Citations: 15     Fields:    Translation:HumansCells
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