Leukocyte Common Antigens
"Leukocyte Common Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain two FIBRONECTIN TYPE III DOMAINS and possess cytoplasmic protein tyrosine phosphatase activity, which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. Leukocyte common antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons.
| Descriptor ID |
D017493
|
| MeSH Number(s) |
D08.811.277.352.650.775.400.100.500 D12.644.360.587.100.500 D12.776.476.592.100.500 D12.776.543.733.937.500
|
| Concept/Terms |
Leukocyte Common Antigens- Leukocyte Common Antigens
- Antigens, Leukocyte Common
- CD45 Antigens
- Antigens, CD45
- Protein Tyrosine Phosphatase, Receptor Type, C
- L-CA Antigens
- Antigens, L-CA
- L CA Antigens
- Leukocyte Common Antigen
- Antigen, Leukocyte Common
- CD45 Antigen
- Antigen, CD45
- T200 Antigens
- Antigens, T200
CD45RO Antigens- CD45RO Antigens
- Antigens, CD45RO
- CD45R0 Antigens
- Antigens, CD45R0
B220 Antigens- B220 Antigens
- Antigens, B220
- CD45R Antigens
- Antigens, CD45R
- B220 Antigen
- Antigen, B220
|
Below are MeSH descriptors whose meaning is more general than "Leukocyte Common Antigens".
Below are MeSH descriptors whose meaning is more specific than "Leukocyte Common Antigens".
This graph shows the total number of publications written about "Leukocyte Common Antigens" by people in this website by year, and whether "Leukocyte Common Antigens" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 1 | 1 | 2 |
| 2010 | 0 | 2 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leukocyte Common Antigens" by people in Profiles.
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Conditional Deletion of Bmal1 Accentuates Microvascular and Macrovascular Injury. Am J Pathol. 2017 Jun; 187(6):1426-1435.
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Membrane-cytoskeleton interactions in cholesterol-dependent domain formation. Essays Biochem. 2015; 57:177-87.
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Dendritic cell populations with different concentrations of lipid regulate tolerance and immunity in mouse and human liver. Gastroenterology. 2012 Oct; 143(4):1061-72.
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Intravesical chondroitin sulfate inhibits recruitment of inflammatory cells in an acute acid damage "leaky bladder" model of cystitis. Urology. 2012 Feb; 79(2):483.e13-7.
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Memory/effector (CD45RB(lo)) CD4 T cells are controlled directly by IL-10 and cause IL-22-dependent intestinal pathology. J Exp Med. 2011 May 09; 208(5):1027-40.
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Surface phenotype and functionality of WNV specific T cells differ with age and disease severity. PLoS One. 2010 Dec 13; 5(12):e15343.
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IL-6 increases B-cell IgG production in a feed-forward proinflammatory mechanism to skew hematopoiesis and elevate myeloid production. Blood. 2010 Jun 10; 115(23):4699-706.
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Key developmental transitions in human germinal center B cells are revealed by differential CD45RB expression. Blood. 2009 Apr 23; 113(17):3999-4007.
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Human B cell subsets. Adv Immunol. 2008; 98:151-224.
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Conjunctival lymphoid follicles in new world rodents. Anat Rec (Hoboken). 2007 Sep; 290(9):1190-4.