HSP70 Heat-Shock Proteins

"HSP70 Heat-Shock Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of MOLECULAR CHAPERONES found in both prokaryotes and in several compartments of eukaryotic cells. These proteins can interact with polypeptides during a variety of assembly processes in such a way as to prevent the formation of nonfunctional structures.

Descriptor ID	D018840
MeSH Number(s)	D12.776.580.216.375
Concept/Terms	HSP70 Heat-Shock Proteins HSP70 Heat-Shock Proteins HSP70 Heat Shock Proteins Heat-Shock Proteins, HSP70 Heat-Shock Protein 70 Heat Shock Protein 70 Heat-Shock Proteins 70 Heat Shock Proteins 70 Heat Shock 70 kDa Protein

Below are MeSH descriptors whose meaning is more general than "HSP70 Heat-Shock Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Molecular Chaperones [D12.776.580]
Heat-Shock Proteins [D12.776.580.216]
HSP70 Heat-Shock Proteins [D12.776.580.216.375]

Below are MeSH descriptors whose meaning is related to "HSP70 Heat-Shock Proteins".

Below are MeSH descriptors whose meaning is more specific than "HSP70 Heat-Shock Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "HSP70 Heat-Shock Proteins" by people in this website by year, and whether "HSP70 Heat-Shock Proteins" was a major or minor topic of these publications.

Bar chart showing 20 publications over 14 distinct years, with a maximum of 3 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	1	1	2
1999	1	0	1
2002	1	0	1
2004	1	1	2
2005	1	1	2
2010	1	0	1
2011	0	1	1
2012	1	1	2
2013	1	0	1
2014	1	0	1
2015	0	1	1
2017	0	1	1
2018	1	2	3
2020	1	0	1

Below are the most recent publications written about "HSP70 Heat-Shock Proteins" by people in Profiles.

Ramraj SK, Elayapillai SP, Pelikan RC, Zhao YD, Isingizwe ZR, Kennedy AL, Lightfoot SA, Benbrook DM. Novel ovarian cancer maintenance therapy targeted at mortalin and mutant p53. Int J Cancer. 2020 08 15; 147(4):1086-1097.

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Zhou B, Song J, Wang M, Wang X, Wang J, Howard EW, Zhou F, Qu J, Chen WR. BSA-bioinspired gold nanorods loaded with immunoadjuvant for the treatment of melanoma by combined photothermal therapy and immunotherapy. Nanoscale. 2018 Nov 29; 10(46):21640-21647.

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Watts FM, Pouland T, Bunce RA, Berlin KD, Benbrook DM, Mashayekhi M, Bhandari D, Zhou D. Activity of oxygen-versus sulfur-containing analogs of the Flex-Het anticancer agent SHetA2. Eur J Med Chem. 2018 Oct 05; 158:720-732.

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Que NLS, Crowley VM, Duerfeldt AS, Zhao J, Kent CN, Blagg BSJ, Gewirth DT. Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding. J Med Chem. 2018 04 12; 61(7):2793-2805.

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Ding XS, Mannas SW, Bishop BA, Rao X, Lecoultre M, Kwon S, Nelson RS. An Improved Brome mosaic virus Silencing Vector: Greater Insert Stability and More Extensive VIGS. Plant Physiol. 2018 01; 176(1):496-510.

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Yamada HY, Zhang Y, Reddy A, Mohammed A, Lightfoot S, Dai W, Rao CV. Tumor-promoting/progressing role of additional chromosome instability in hepatic carcinogenesis in Sgo1 (Shugoshin 1) haploinsufficient mice. Carcinogenesis. 2015 Apr; 36(4):429-40.

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Boswell-Casteel RC, Johnson JM, Duggan KD, Tsutsui Y, Hays FA. Overproduction and biophysical characterization of human HSP70 proteins. Protein Expr Purif. 2015 Feb; 106:57-65.

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Benbrook DM, Nammalwar B, Long A, Matsumoto H, Singh A, Bunce RA, Berlin KD. SHetA2 interference with mortalin binding to p66shc and p53 identified using drug-conjugated magnetic microspheres. Invest New Drugs. 2014 Jun; 32(3):412-23.

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Hoeppner LH, Phoenix KN, Clark KJ, Bhattacharya R, Gong X, Sciuto TE, Vohra P, Suresh S, Bhattacharya S, Dvorak AM, Ekker SC, Dvorak HF, Claffey KP, Mukhopadhyay D. Revealing the role of phospholipase Cß3 in the regulation of VEGF-induced vascular permeability. Blood. 2012 Sep 13; 120(11):2167-73.

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Duerfeldt AS, Peterson LB, Maynard JC, Ng CL, Eletto D, Ostrovsky O, Shinogle HE, Moore DS, Argon Y, Nicchitta CV, Blagg BS. Development of a Grp94 inhibitor. J Am Chem Soc. 2012 Jun 13; 134(23):9796-804.

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