"Germinal Center" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The activated center of a lymphoid follicle in secondary lymphoid tissue where B-LYMPHOCYTES are stimulated by antigens and helper T cells (T-LYMPHOCYTES, HELPER-INDUCER) are stimulated to generate memory cells.
| Descriptor ID |
D018858
|
| MeSH Number(s) |
A10.549.400.500 A15.382.520.604.412.500
|
| Concept/Terms |
Germinal Center- Germinal Center
- Center, Germinal
- Centers, Germinal
- Germinal Centers
|
Below are MeSH descriptors whose meaning is more general than "Germinal Center".
Below are MeSH descriptors whose meaning is more specific than "Germinal Center".
This graph shows the total number of publications written about "Germinal Center" by people in this website by year, and whether "Germinal Center" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2008 | 2 | 1 | 3 |
| 2010 | 1 | 0 | 1 |
| 2015 | 2 | 2 | 4 |
| 2018 | 2 | 0 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Germinal Center" by people in Profiles.
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The RNA-binding protein HuR is required for maintenance of the germinal centre response. Nat Commun. 2021 11 12; 12(1):6556.
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Efficient homing of antibody-secreting cells to the bone marrow requires RNA-binding protein ZFP36L1. J Exp Med. 2021 03 01; 218(3).
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Broadly Reactive Influenza Antibodies Are Not Limited by Germinal Center Competition with High-Affinity Antibodies. mBio. 2020 11 03; 11(6).
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Role of TFH Cells in Promoting T Helper 17-Induced Neuroinflammation. Front Immunol. 2018; 9:382.
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The RNA-binding protein PTBP1 is necessary for B cell selection in germinal centers. Nat Immunol. 2018 03; 19(3):267-278.
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GIMAP1 Is Essential for the Survival of Naive and Activated B Cells In Vivo. J Immunol. 2016 Jan 01; 196(1):207-16.
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Overlapping Morphologic and Immunohistochemical Features of Hashimoto Thyroiditis and IgG4-Related Thyroid Disease. Endocr Pathol. 2015 May; 26(2):170-7.
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The RNA-binding protein HuR is essential for the B cell antibody response. Nat Immunol. 2015 Apr; 16(4):415-25.
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CD1d-dependent expansion of NKT follicular helper cells in vivo and in vitro is a product of cellular proliferation and differentiation. Int Immunol. 2015 May; 27(5):253-63.
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Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction. J Immunol. 2010 Oct 01; 185(7):4042-52.