"Trinucleotide Repeats" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Microsatellite repeats consisting of three nucleotides dispersed in the euchromatic arms of chromosomes.
| Descriptor ID |
D018911
|
| MeSH Number(s) |
G02.111.570.080.708.800.500.850 G05.360.080.708.800.500.850 G05.360.340.024.850.500.850
|
| Concept/Terms |
Trinucleotide Repeats- Trinucleotide Repeats
- Repeat, Trinucleotide
- Repeats, Trinucleotide
- Trinucleotide Repeat
- Triplet Repeats
- Repeat, Triplet
- Repeats, Triplet
- Triplet Repeat
|
Below are MeSH descriptors whose meaning is more general than "Trinucleotide Repeats".
Below are MeSH descriptors whose meaning is more specific than "Trinucleotide Repeats".
This graph shows the total number of publications written about "Trinucleotide Repeats" by people in this website by year, and whether "Trinucleotide Repeats" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 2 | 0 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Trinucleotide Repeats" by people in Profiles.
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FXN Promoter Silencing in the Humanized Mouse Model of Friedreich Ataxia. PLoS One. 2015; 10(9):e0138437.
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Altered nucleosome positioning at the transcription start site and deficient transcriptional initiation in Friedreich ataxia. J Biol Chem. 2014 May 30; 289(22):15194-202.
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Role of transcript and interplay between transcription and replication in triplet-repeat instability in mammalian cells. Nucleic Acids Res. 2011 Jan; 39(2):526-35.
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Somatic instability of the expanded GAA triplet-repeat sequence in Friedreich ataxia progresses throughout life. Genomics. 2007 Jul; 90(1):1-5.
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The GAA triplet-repeat is unstable in the context of the human FXN locus and displays age-dependent expansions in cerebellum and DRG in a transgenic mouse model. Hum Genet. 2007 Jan; 120(5):633-40.
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The structural basis of myotonic dystrophy from the crystal structure of CUG repeats. Proc Natl Acad Sci U S A. 2005 Nov 15; 102(46):16626-31.
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Friedreich ataxia in carriers of unstable borderline GAA triplet-repeat alleles. Ann Neurol. 2004 Dec; 56(6):898-901.
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Analysis of unstable triplet repeats using small-pool polymerase chain reaction. Methods Mol Biol. 2004; 277:61-76.
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The GAA triplet-repeat sequence in Friedreich ataxia shows a high level of somatic instability in vivo, with a significant predilection for large contractions. Hum Mol Genet. 2002 Sep 01; 11(18):2175-87.
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A mild case of Friedreich ataxia: lymphocyte and sural nerve analysis for GAA repeat length reveals somatic mosaicism. Muscle Nerve. 1998 Mar; 21(3):390-3.