Hypoplastic Left Heart Syndrome
"Hypoplastic Left Heart Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition caused by underdevelopment of the whole left half of the heart. It is characterized by hypoplasia of the left cardiac chambers (HEART ATRIUM; HEART VENTRICLE), the AORTA, the AORTIC VALVE, and the MITRAL VALVE. Severe symptoms appear in early infancy when DUCTUS ARTERIOSUS closes.
Descriptor ID |
D018636
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MeSH Number(s) |
C14.240.400.625 C14.280.400.625 C16.131.240.400.625
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hypoplastic Left Heart Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Hypoplastic Left Heart Syndrome".
This graph shows the total number of publications written about "Hypoplastic Left Heart Syndrome" by people in this website by year, and whether "Hypoplastic Left Heart Syndrome" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 1 | 0 | 1 |
2005 | 1 | 0 | 1 |
2007 | 2 | 0 | 2 |
2012 | 2 | 0 | 2 |
2013 | 1 | 0 | 1 |
2014 | 4 | 0 | 4 |
2015 | 2 | 0 | 2 |
2016 | 1 | 0 | 1 |
2017 | 2 | 0 | 2 |
2019 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hypoplastic Left Heart Syndrome" by people in Profiles.
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Parker LE, Landstrom AP. Genetic Etiology of Left-Sided Obstructive Heart Lesions: A Story in Development. J Am Heart Assoc. 2021 01 19; 10(2):e019006.
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Vincenti M, O'Leary PW, Qureshi MY, Seisler DK, Burkhart HM, Cetta F, Nelson TJ. Clinical Impact of Autologous Cell Therapy on Hypoplastic Left Heart Syndrome After Bidirectional Cavopulmonary Anastomosis. Semin Thorac Cardiovasc Surg. 2021; 33(3):791-801.
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Burkhart HM, Qureshi MY, Rossano JW, Cantero Peral S, O'Leary PW, Hathcock M, Kremers W, Nelson TJ. Autologous stem cell therapy for hypoplastic left heart syndrome: Safety and feasibility of intraoperative intramyocardial injections. J Thorac Cardiovasc Surg. 2019 12; 158(6):1614-1623.
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Burkhart HM, Mir A, Thompson JL. Hypoplastic left heart syndrome and the allure of a valved conduit. J Thorac Cardiovasc Surg. 2018 04; 155(4):1745-1746.
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Burkhart HM, Thompson JL, Mir A. The importance of arch geometry after Norwood reconstruction. J Thorac Cardiovasc Surg. 2017 10; 154(4):1385-1386.
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Burkhart HM, Thompson JL. The "right" way to repair recoarctation after the Norwood operation. J Thorac Cardiovasc Surg. 2016 12; 152(6):1624-1625.
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Burkhart HM, Thompson JL, Nelson TJ. Hypoplastic left heart syndrome: What's next? J Thorac Cardiovasc Surg. 2016 Apr; 151(4):909-10.
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Mir A, Frank S, Journeycake J, Wolovitis J, Guleserian K, Heistein L, Lemler M. Aspirin Resistance in Single-Ventricle Physiology: Aspirin Prophylaxis Is Not Adequate to Inhibit Platelets in the Immediate Postoperative Period. Ann Thorac Surg. 2015 Jun; 99(6):2158-64.
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Burkhart HM, Qureshi MY, Peral SC, O'Leary PW, Olson TM, Cetta F, Nelson TJ. Regenerative therapy for hypoplastic left heart syndrome: first report of intraoperative intramyocardial injection of autologous umbilical-cord blood-derived cells. J Thorac Cardiovasc Surg. 2015 Mar; 149(3):e35-7.
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Peral SC, Burkhart HM, Nelson TJ. Utilization of stem cells to treat congenital heart disease: hype and hope. Curr Opin Pediatr. 2014 Oct; 26(5):553-60.