"Monocrotaline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes are noted after oral magnesium treatment.
| Descriptor ID |
D016686
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| MeSH Number(s) |
D03.132.716.500 D03.633.100.772.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Monocrotaline".
Below are MeSH descriptors whose meaning is more specific than "Monocrotaline".
This graph shows the total number of publications written about "Monocrotaline" by people in this website by year, and whether "Monocrotaline" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Monocrotaline" by people in Profiles.
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Monocrotaline-Induced Pulmonary Hypertension Involves Downregulation of Antiaging Protein Klotho and eNOS Activity. Hypertension. 2016 11; 68(5):1255-1263.
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Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats. Hypertension. 2009 Sep; 54(3):668-75.
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Comparison of lung proteome profiles in two rodent models of pulmonary arterial hypertension. Proteomics. 2007 Jul; 7(14):2469-78.