Peptide Elongation Factor 1
"Peptide Elongation Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peptide elongation factor 1 is a multisubunit protein that is responsible for the GTP-dependent binding of aminoacyl-tRNAs to eukaryotic ribosomes. The alpha subunit (EF-1alpha) binds aminoacyl-tRNA and transfers it to the ribosome in a process linked to GTP hydrolysis. The beta and delta subunits (EF-1beta, EF-1delta) are involved in exchanging GDP for GTP. The gamma subunit (EF-1gamma) is a structural component.
| Descriptor ID |
D020648
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| MeSH Number(s) |
D08.811.277.040.330.300.100.101 D12.776.157.325.150.101 D12.776.835.700.350.101
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Peptide Elongation Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Peptide Elongation Factor 1".
This graph shows the total number of publications written about "Peptide Elongation Factor 1" by people in this website by year, and whether "Peptide Elongation Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2002 | 2 | 0 | 2 |
| 2003 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Peptide Elongation Factor 1" by people in Profiles.
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Marshall DC, Hill KB, Marske KA, Chambers C, Buckley TR, Simon C. Limited, episodic diversification and contrasting phylogeography in a New Zealand cicada radiation. BMC Evol Biol. 2012 Sep 11; 12:177.
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Broughton RE, Harrison RG. Nuclear gene genealogies reveal historical, demographic and selective factors associated with speciation in field crickets. Genetics. 2003 Apr; 163(4):1389-401.
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Budkevich TV, Timchenko AA, Tiktopulo EI, Negrutskii BS, Shalak VF, Petrushenko ZM, Aksenov VL, Willumeit R, Kohlbrecher J, Serdyuk IN, El'skaya AV. Extended conformation of mammalian translation elongation factor 1A in solution. Biochemistry. 2002 Dec 24; 41(51):15342-9.
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Petrushenko ZM, Budkevich TV, Shalak VF, Negrutskii BS, El'skaya AV. Novel complexes of mammalian translation elongation factor eEF1A.GDP with uncharged tRNA and aminoacyl-tRNA synthetase. Implications for tRNA channeling. Eur J Biochem. 2002 Oct; 269(19):4811-8.
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Petrushenko ZM, Negrutskii BS, Ladokhin AS, Budkevich TV, Shalak VF, El'skaya AV. Evidence for the formation of an unusual ternary complex of rabbit liver EF-1alpha with GDP and deacylated tRNA. FEBS Lett. 1997 Apr 21; 407(1):13-7.
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Ge Q, Wu Y, Trieu EP, Targoff IN. Analysis of the specificity of anti-PM-Scl autoantibodies. Arthritis Rheum. 1994 Oct; 37(10):1445-52.