"RGS Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large family of evolutionarily conserved proteins that function as negative regulators of HETEROTRIMERIC GTP-BINDING PROTEINS. RGS PROTEINS act by increasing the GTPase activity of the G alpha subunit of a heterotrimeric GTP-binding protein, causing it to revert to its inactive (GDP-bound) form.
| Descriptor ID |
D020710
|
| MeSH Number(s) |
D12.644.360.325.150.750 D12.776.476.325.150.750
|
| Concept/Terms |
RGS Proteins- RGS Proteins
- Regulators of G-Protein Signaling Proteins
- Regulators of G Protein Signaling Proteins
- RGS Protein (G-Protein Signaling)
|
Below are MeSH descriptors whose meaning is more general than "RGS Proteins".
Below are MeSH descriptors whose meaning is more specific than "RGS Proteins".
This graph shows the total number of publications written about "RGS Proteins" by people in this website by year, and whether "RGS Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 2 | 0 | 2 |
| 2002 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "RGS Proteins" by people in Profiles.
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Novel identified associations of RGS1 and RASGRP1 variants in IgA Nephropathy. Sci Rep. 2016 11 02; 6:35781.
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Epigenetic repression of regulator of G-protein signaling 2 promotes androgen-independent prostate cancer cell growth. Int J Cancer. 2012 Apr 01; 130(7):1521-31.
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CRTC3 links catecholamine signalling to energy balance. Nature. 2010 Dec 16; 468(7326):933-9.
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Regulation of stress response signaling by the N-terminal dishevelled/EGL-10/pleckstrin domain of Sst2, a regulator of G protein signaling in Saccharomyces cerevisiae. J Biol Chem. 2002 Jun 21; 277(25):22156-67.
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Effects of regulators of G protein-signaling proteins on the functional response of the mu-opioid receptor in a melanophore-based assay. J Pharmacol Exp Ther. 1999 Nov; 291(2):482-91.
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Interaction between RGS7 and polycystin. Proc Natl Acad Sci U S A. 1999 May 25; 96(11):6371-6.