"Isoprostanes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A series of prostaglandin-like compounds that are produced by the attack of free-radical species on unsaturated fatty acids, especially ARACHIDONIC ACID, of cellular MEMBRANES. Once cleaved from the lipid membrane by the action of phospholipases they can circulate into various bodily fluids and eventually be excreted. Although these compounds resemble enzymatically synthesized prostaglandins their stereoisometric arrangement is usually different than the "naturally occurring" compounds.
Below are MeSH descriptors whose meaning is more general than "Isoprostanes".
Below are MeSH descriptors whose meaning is more specific than "Isoprostanes".
This graph shows the total number of publications written about "Isoprostanes" by people in this website by year, and whether "Isoprostanes" was a major or minor topic of these publications.
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Below are the most recent publications written about "Isoprostanes" by people in Profiles.
Oxidative stress-induced isoprostane formation may contribute to aspirin resistance in platelets. Prostaglandins Leukot Essent Fatty Acids. 2002 May-Jun; 66(5-6):557-8.