"Aryldialkylphosphatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme which catalyzes the hydrolysis of an aryl-dialkyl phosphate to form dialkyl phosphate and an aryl alcohol. It can hydrolyze a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. It may also mediate an enzymatic protection of LOW DENSITY LIPOPROTEINS against oxidative modification and the consequent series of events leading to ATHEROMA formation. The enzyme was previously regarded to be identical with Arylesterase (EC 3.1.1.2).
| Descriptor ID |
D043303
|
| MeSH Number(s) |
D08.811.277.352.660.500
|
| Concept/Terms |
Aryldialkylphosphatase- Aryldialkylphosphatase
- Arylalkylphosphatase
- Homocysteine Thiolactone Hydrolase
- Hydrolase, Homocysteine Thiolactone
- Thiolactone Hydrolase, Homocysteine
- OPA Anhydrase
- Anhydrase, OPA
- Paraoxonase
- Organophosphorus Acid Anhydrase
- Acid Anhydrase, Organophosphorus
- Anhydrase, Organophosphorus Acid
- Organophosphorus Acid Anhydrolase
- Acid Anhydrolase, Organophosphorus
- Anhydrolase, Organophosphorus Acid
- Organophosphorus Acid Hydrolase
- Acid Hydrolase, Organophosphorus
- Hydrolase, Organophosphorus Acid
- Organophosphorus Hydrolase
- Hydrolase, Organophosphorus
- Aryl-dialkyl Phosphatase
- Aryl dialkyl Phosphatase
- Phosphatase, Aryl-dialkyl
- OPH Enzyme
- Enzyme, OPH
|
Below are MeSH descriptors whose meaning is more general than "Aryldialkylphosphatase".
Below are MeSH descriptors whose meaning is more specific than "Aryldialkylphosphatase".
This graph shows the total number of publications written about "Aryldialkylphosphatase" by people in this website by year, and whether "Aryldialkylphosphatase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Aryldialkylphosphatase" by people in Profiles.
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Alzheimer's Disease Markers in Aged ApoE-PON1 Deficient Mice. J Alzheimers Dis. 2019; 67(4):1353-1365.
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Paraoxonase 1 polymorphisms as the risk factor of coronary heart disease in a Thai population. Acta Cardiol. 2010 Dec; 65(6):681-91.
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Genetic variation in the paraoxonase-3 (PON3) gene is associated with serum PON1 activity. Ann Hum Genet. 2008 Jan; 72(Pt 1):72-81.
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The codon 55 polymorphism in the paraoxonase 1 gene is not associated with the risk of coronary heart disease in Asian Indians and Chinese. Atherosclerosis. 1998 Feb; 136(2):217-23.
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DNA polymorphisms in two paraoxonase genes (PON1 and PON2) are associated with the risk of coronary heart disease. Am J Hum Genet. 1998 Jan; 62(1):36-44.
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Genetic polymorphism of paraoxonase and the risk of coronary heart disease. Arterioscler Thromb Vasc Biol. 1997 Jun; 17(6):1067-73.