"Transglutaminases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transglutaminases catalyze cross-linking of proteins at a GLUTAMINE in one chain with LYSINE in another chain. They include keratinocyte transglutaminase (TGM1 or TGK), tissue transglutaminase (TGM2 or TGC), plasma transglutaminase involved with coagulation (FACTOR XIII and FACTOR XIIIa), hair follicle transglutaminase, and prostate transglutaminase. Although structures differ, they share an active site (YGQCW) and strict CALCIUM dependence.
| Descriptor ID |
D011503
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| MeSH Number(s) |
D08.811.913.050.200.800
|
| Concept/Terms |
Transglutaminases- Transglutaminases
- Protein-Glutamine gamma-Glutamyltransferases
- Protein Glutamine gamma Glutamyltransferases
- gamma-Glutamyltransferases, Protein-Glutamine
- Glutaminyl-Peptide Gamma-Glutamyltransferases
- Gamma-Glutamyltransferases, Glutaminyl-Peptide
- Glutaminyl Peptide Gamma Glutamyltransferases
|
Below are MeSH descriptors whose meaning is more general than "Transglutaminases".
Below are MeSH descriptors whose meaning is more specific than "Transglutaminases".
This graph shows the total number of publications written about "Transglutaminases" by people in this website by year, and whether "Transglutaminases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transglutaminases" by people in Profiles.
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Comparison of celiac disease markers in women with early recurrent pregnancy loss and normal controls. Am J Reprod Immunol. 2019 07; 82(1):e13127.
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Cystamine preparations exhibit anticoagulant activity. PLoS One. 2015; 10(4):e0124448.
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Immunological indicators of coeliac disease activity are not altered by long-term oats challenge. Clin Exp Immunol. 2013 Mar; 171(3):313-8.
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Deamidation and transamidation of substance P by tissue transglutaminase revealed by electron-capture dissociation fourier transform mass spectrometry. Chemistry. 2011 Jan 10; 17(2):486-97.
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A single amino acid substitution in the enzymatic domain of cytotoxic necrotizing factor type 1 of Escherichia coli alters the tissue culture phenotype to that of the dermonecrotic toxin of Bordetella spp. Mol Microbiol. 2006 May; 60(4):939-50.
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Expression of transglutaminase substrate activity on Candida albicans germ tubes through a coiled, disulfide-bonded N-terminal domain of Hwp1 requires C-terminal glycosylphosphatidylinositol modification. J Biol Chem. 2004 Sep 24; 279(39):40737-47.
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Crosslinking of alpha 2-antiplasmin to fibrin. Ann N Y Acad Sci. 2001; 936:335-9.
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Cross-linking of wild-type and mutant alpha 2-antiplasmins to fibrin by activated factor XIII and by a tissue transglutaminase. J Biol Chem. 2000 Dec 01; 275(48):37382-9.
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Synthesis, structure-activity relationships, and RARgamma-ligand interactions of nitrogen heteroarotinoids. J Med Chem. 1999 Sep 09; 42(18):3602-14.
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Markers of keratinocyte differentiation in snuff-induced leukoplakia. Am J Surg. 1992 Dec; 164(6):563-6.